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PTU 100mg Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 13 Mar 2026 | 01:39 PM (IST)
PTU 100mg Tablet belongs to a group of medicine called anti-thyroid agents. It is used in the treatment of hyperthyroidism. It works by reducing the production of a hormone called thyroxine by the thyroid gland.
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General Information

Contains

Propyl Thiouracil (100mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
PTU 100mg Tablet image
PTU 100mg Tablet image

Product introduction

PTU 100mg Tablet may be used alone or in combination with other medicines. It can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.


There is limited data on the side effects of PTU 100mg Tablet. Let your doctor know if you experience any symptoms that bother you or worsen while taking the medicine. They may be able to suggest ways to treat or manage the side effects.


Before you start PTU 100mg Tablet, let your doctor know if you have any medical conditions. Inform your doctor about all the medications you are taking, as some medicines may interact with PTU 100mg Tablet. Pregnant or breastfeeding women should consult their doctor before taking PTU 100mg Tablet to ensure safety.

Uses of PTU Tablet

Benefits of PTU Tablet

Treatment of Hyperthyroidism
Hyperthyroidism is a condition in which the thyroid gland produces excessive thyroid hormones, leading to symptoms like rapid heartbeat, weight loss, anxiety, and excessive sweating. PTU 100mg Tablet helps control the overproduction of these hormones, easing symptoms, restoring hormonal balance, and improving overall health and well-being.

Side effects of PTU Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of PTU
  • Limited data available

How to use PTU Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. PTU 100mg Tablet may be taken with or without food.

How PTU Tablet works

PTU 100mg Tablet works by reducing the thyroid hormones produced by the thyroid gland.

Quick tips

  • PTU 100mg Tablet is used for the treatment of hyperthyroidism.
  • You may have to stop taking it for a while if you are also taking radio-iodine as a treatment for your overactive thyroid. 
  • It may affect the level of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness.
  • Stop taking PTU 100mg Tablet and Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with PTU 100mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of PTU 100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
PTU 100mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of PTU 100mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
PTU 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

PTU 100mg Tablet is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It helps restore hormone balance and reduce symptoms such as rapid heartbeat, weight loss, and anxiety.
PTU 100mg Tablet does not usually cure hyperthyroidism permanently. They control thyroid hormone production, but long-term treatment, or other options such as surgery or radioiodine, may still be needed.
PTU 100mg Tablet should not be taken by people if they are allergic to propylthiouracil or have had severe reactions like agranulocytosis (severely low neutrophil levels), hepatitis (inflammation of the liver), vasculitis (inflammation of blood vessels), or nephritis (inflammation of the kidneys) from it in the past. People with rare sugar absorption disorders should also avoid it.
PTU 100mg Tablet should not be given to children under 6 years old due to safety concerns. For children aged 6 and above, they may be used under strict medical supervision.
Regular blood tests are necessary when taking PTU 100mg Tablet to check thyroid hormone levels, white blood cells, and liver function. This helps prevent complications like overdosing, agranulocytosis, or liver damage.
While you are on PTU 100mg Tablet, you should contact your doctor immediately if you develop symptoms like sore throat, fever, mouth ulcers, unexplained bruising, yellowing of the skin or eyes, or severe tiredness. These may indicate serious blood or liver problems.

Fact Box

Chemical Class

Thiourea derivative

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Antithyroid Agents

Related lab tests

Anti Thyroglobulin Antibody

Thyroid Stimulating Hormone

Thyroxine - Free

Thyroxine - Total

References

  1. Propyl Thiouracil. Wrexham: Wockhardt UK Ltd.; 2008 [revised 16 Nov. 2015]. [Accessed 04 Apr. 2019] (online) Available from:
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1165-67.
  3. Propylthiouracil [FDA Label]. Fort Lee, NJ: DAVA Pharmaceuticals, Inc.; 2010. [Accessed 03 Sept. 2020] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

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