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Propyl Thiouracil



Propylthiouracil is used to treat hyperthyroidism (a condition in which thyroid gland produces excessive thyroid hormones).

How it works

Propylthiouracil belongs to a class of drugs called as antithyroid agents. It acts by interfering with the uptake of iodine by thyroid gland thereby preventing it from making excess thyroid hormones.

Common side effects

Neck pain, Tingling sensation of extremity, Numbness of extremity, Dizziness, Altered taste, Hair loss, Muscle pain, Joint pain


  • 1 variant(s)

Expert advice

  • Propylthiouracil is not recommended in children below 6 years of age. 
  • Inform your doctor if you are receiving medications for heart diseases, high blood pressure, asthma or any other heart or lung disorder.
  • Use propylthiouracil with caution if you are a patient with kidney or liver disease.
  • Discontinue propylthiouracil immediately if you develop symptoms of liver dysfunction (characterized by anorexia, pruritus, right upper quadrant pain, etc.).
  • Seek immediate medical attention if you experience sore throat, fever, mouth ulcers, bruising, unusual tiredness, non-specific illness or other symptoms of infection.
  • You will be monitored for prothrombin time during propylthiouracil therapy.
  • Tell your doctor if you are pregnant or think you may become pregnant or breast-feeding.
  • Avoid if Patient is allergic to propylthiouracil or any of its ingredients. 
  • Do not give if Children is <6 years. 
  • Avoid if Patients has previously reported intolerance to certain sugars.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)