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Prota 50mg Injection 1
Prota 50mg Injection 2

Prota 50mg Injection

Protamine sulfate (50mg)
Genuine
Authenticity Assured
Prescription
required
NPPA Regulated
Show Details
Prota 50mg Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 Nov 2026 | 01:01 AM (IST)
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5 ml Injection
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Product expires after Nov, 2027

Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.

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General Information

Contains

Protamine sulfate (50mg)

Marketer

Samarth Life Sciences Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Prota 50mg Injection 1
Prota 50mg Injection 2

Product introduction

Prota 50mg Injection is used to stop bleeding in patients caused by heparin

Uses of Prota Injection

  • Heparin overdose

Benefits of Prota Injection

Heparin overdose
Heparin overdose can lead to excessive bleeding because it thins the blood more than needed, which may occur during or after surgery or medical treatment. Prota 50mg Injection helps stop the bleeding by reversing the effects of heparin. It stabilizes the blood’s ability to clot properly, reducing the risk of serious bleeding complications and supporting a safe and quicker recovery.

Side effects of Prota Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prota
  • Injection site reactions (pain, swelling, redness)

How to use Prota Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Prota Injection works

Prota 50mg Injection is used to counteract the anticoagulant effect of heparin and is used to stop bleeding in patients caused by heparin.

Quick tips

  • Prota 50mg Injection helps neutralize the effect of anti-clotting medicine heparin.
  • It should not be used to reverse the effects of other anti-clotting medicines (anticoagulants) such as warfarin.
  • It should be used under medical supervision. Do not self-administer.
  • Inform your doctor if you experience a sudden fall in blood pressure, breathlessness, or chest and abdominal pain when receiving Prota 50mg Injection.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Prota 50mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Prota 50mg Injection during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Prota 50mg Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Prota 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Prota 50mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Prota 50mg Injection in patients with liver disease.

Frequently asked questions

Prota 50mg Injection is used to reverse the blood-thinning effect of heparin when too much heparin has been given or its effect needs to be reversed.
Prota 50mg Injection is given slowly into a vein by a trained healthcare professional. Your blood clotting levels, blood pressure and heart rate may be monitored during and after treatment.
No. Prota 50mg Injection is used to reverse the effect of heparin. It does not reverse the effects of other blood thinners, such as warfarin.
Yes. In rare cases, Prota 50mg Injection can cause a severe allergic or other serious reaction. Tell your doctor if you have received it before, use insulin containing medicines, have had a vasectomy, or have a fish allergy. Seek immediate medical attention if you develop difficulty breathing, chest discomfort or a sudden drop in blood pressure.
Blood clotting tests help your doctor check whether the effect of heparin has been adequately neutralised. Further monitoring may be needed because bleeding or the blood-thinning effect can sometimes return after treatment.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

OTHERS

Action Class

Heparin Antagonists

Related lab tests

Activated Partial Thromboplastin Time

Prothrombin Time

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1167-68.
  2. Protamine. Lake Zurich, Illinois: Fresenius Kabi; 2016. [Accessed 06 Apr. 2019] (online) Available from:
  3. Protamine sulfate. Wrexham: Wockhardt UK Ltd.; 1991 [revised 4 May 2018]. [Accessed 6 Apr. 2019] (online) Available from:
  4. Protamine sulfate [Product monograph]. Fresenius Kabi Canada Ltd.; 2016. [Accessed 27 Oct 2026]. (online) Available from:
  6. Protamine sulfate [Product monograph]. Sandoz Canada Inc.; 2026. [Accessed 27 Oct 2026]. (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Prota 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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