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Priunta 150mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 17 Dec 2025 | 04:35 PM (IST)
Priunta 150mg Injection is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor receptor protein).
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Stored between 2-8°C
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Kintsugi 150mg Injection
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Priunta 150mg Injection
Priunta 150mg Injection
vial of 7.2 ml Injection
₹18587
₹20405.55
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Kintsugi 150mg Injection
Kintsugi 150mg Injection
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General Information

Contains

Trastuzumab (150mg)

Marketer

Abbott

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Priunta 150mg Injection image
Priunta 150mg Injection image

Product introduction

Priunta 150mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must have to inform your doctor if you experience breathlessness, cough, shivering, swelling of legs and arm.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Priunta Injection

Benefits of Priunta Injection

Breast cancer
Breast cancer occurs when cells in the breast grow uncontrollably, often forming a lump or mass. Priunta 150mg Injection helps to slow or stop the growth of cancer cells. It may also help shrink the tumor and prevent the cancer from coming back. It improves treatment outcomes, offers patients a better chance of recovery, reduces the risk of relapse, and brings hope for a longer and healthier life.
Stomach cancer
Stomach cancer, also known as gastric cancer, can cause symptoms like indigestion, weight loss, and stomach pain. Priunta 150mg Injection helps to slow tumor growth and improve the effect of other cancer treatments. This targeted approach enhances treatment success, helps control the disease more effectively, and can extend survival, allowing patients to maintain a better quality of life.

Side effects of Priunta Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Priunta
  • Anemia (low number of red blood cells)
  • Chills
  • Common cold
  • Cough
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Fatigue
  • Fever
  • Headache
  • Heart failure
  • Infection
  • Insomnia (difficulty in sleeping)
  • Mucosal inflammation
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Taste change
  • Upper respiratory tract infection
  • Weight loss

How to use Priunta Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Priunta Injection works

Priunta 150mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

Quick tips

  • It is given as an injection into your vein or under the skin, usually over 1 hour.
  • Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment. 
  • Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shivering, swelling of legs and arm.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Priunta 150mg Injection may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Priunta 150mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Priunta 150mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Priunta 150mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Priunta 150mg Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Priunta 150mg Injection in patients with liver disease.

Interaction with drugs

Taking Priunta with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Trastuzumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Atazanavir (Oral Route)

Do not consume Trastuzumab with Atazanavir. If concurrent use is essential, watch out for symptoms such as taste change, nausea, diarrhea, vomiting or fatigue. Please consult your doctor. Atazanavir may raise blood levels of Trastuzumab.
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Trastuzumab with Cholera Vaccine (Inactivated).
Severe

Clarithromycin (Oral Route)

Do not consume Trastuzumab with Clarithromycin. If concurrent use is essential, watch out for symptoms such as taste change, nausea, diarrhea, vomiting or fatigue. Please consult your doctor. Clarithromycin may raise blood levels of Trastuzumab.
Severe

Clarithromycin (Injection Route)

Do not consume Trastuzumab with Clarithromycin. If concurrent use is essential, watch out for symptoms such as taste change, nausea, diarrhea, vomiting or fatigue. Please consult your doctor. Clarithromycin may raise blood levels of Trastuzumab.

Frequently asked questions

There are various side effects related to Priunta 150mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Priunta 150mg Injection. You should call your doctor immediately if you notice any such symptoms.
Women of child-bearing age should use effective contraception during Priunta 150mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Priunta 150mg Injection.
Patients with early breast cancer should take Priunta 150mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.
No, fasting is not required before administering Priunta 150mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.
There are 2 different formulations available for administration of Priunta 150mg Injection, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Priunta 150mg Injection intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Priunta 150mg Injection intravenous treatment to Priunta 150mg Injection subcutaneous treatment (and vice versa) if considered appropriate for you.
No, Priunta 150mg Injection cannot be given in patients with HER2 negative cancer cells. Priunta 150mg Injection belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Priunta 150mg Injection binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).
Priunta 150mg Injection when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.
Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Priunta 150mg Injection. Those patients who already have heart-related problems will require investigations every 12 weeks.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anti-HER2 Monoclonal Antibody

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1737.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1390-91.
  4. Trastuzumab. South San Francisco, California: Genentech, Inc.; 1998 [revised Oct. 2010]. [Accessed 27 Mar. 2019] (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trastuzumab. [Updated 2019 Jun 30]. [Accessed 19 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
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