Pretac 0.1% Ointment is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Pretac 0.1% Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.

Use of this medicine may cause some common side effects like erythema, headache, inflammation of hair follicle, and application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.

Uses of Pretac Ointment

Treatment of Atopic dermatitis

Benefits of Pretac Ointment

In Treatment of Atopic dermatitis

Atopic dermatitis, also known as eczema, is a chronic skin condition causing red, itchy, and inflamed patches on the skin, often associated with allergies. Pretac 0.1% Ointment when applied topically suppresses the immune response in the skin, reducing the inflammatory reactions that lead to eczema flare-ups. This way it provides relief and helps improve the quality of life for individuals with atopic dermatitis.

Side effects of Pretac Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pretac

Application site reactions (burning, irritation, itching and redness)
Headache
Hair follicle inflammation

How to use Pretac Ointment

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

How Pretac Ointment works

Pretac 0.1% Ointment is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Pretac 0.1% Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Pretac 0.1% Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Pretac Ointment?

If you miss a dose of Pretac 0.1% Ointment, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pretac 0.1% Ointment

₹24.2/gm of Ointment

Tbis 0.1% Ointment

Eris Lifesciences Ltd

₹55.6/gm of ointment

130% costlier

Tacrovera Forte Ointment

Alkem Laboratories Ltd

₹43.33/gm of ointment

79% costlier

Tacroz Forte Ointment

Glenmark Pharmaceuticals Ltd

₹54.7/gm of ointment

126% costlier

Tacroz Forte Ointment

Glenmark Pharmaceuticals Ltd

₹39.8/gm of ointment

64% costlier

Takfa Forte Ointment

Intas Pharmaceuticals Ltd

₹40.7/gm of ointment

68% costlier

View all substitutes

Quick tips

Pretac 0.1% Ointment is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
It works by decreasing itching, redness, and skin rashes.
Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Pretac 0.1% Ointment. Avoid contact with water after application.
Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Stop using Pretac 0.1% Ointment and consult your doctor if your eczema becomes infected.
Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- Calcineurin inhibitors

Interaction with drugs

Taking Pretac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Clarithromycin (Oral Route) Mild

Clarithromycin may decrease the metabolism of Tacrolimus. Talk to your doctor if you notice any unusual symptoms.

Clarithromycin (Injection Route) Mild

Clarithromycin may decrease the metabolism of Tacrolimus. Talk to your doctor if you notice any unusual symptoms.

View all drug interactions

Patient concerns

Suffering from Atopic dermatitis 15months baby suffering from atopic dermatitis

Dr. Gopal Bansilal Samdani

Paediatrics

Please consult skin specialist

Suffering from severe atopic dermatitis

Dr. Saurav Arora

Homeopathy

Dear sir atopic dermatitis needs supervision and regular follow up, therefore, you need to visit a homeopath personally

Allergic rashes develop in body every week My son is only 2 year and 4 month old, he is very much suffering from allergic rashes over last one year We are looking for a permanent solution for this problem. We are consulting the skin specialist over one but when medicine is stop, Allergies growing between 4 to 7 daysy

Dr. Atul Jain

Dermatology

Your child may hav atopic dermatitisTake care of skin with moisturizer, use baby soap

What is the treatment for atopic dermatitis?

Dr. Souvik Sardar

Dermatology

Hello PATIENT moisturiser is the pillar for treatment of ADApply non irritant moisturiser better to use ceramide rich oneIf there is any inflammation then anti inflammatory creams like topical steroid or calcineurin inhibitors are usePhototherapy is also an effective modalityBt wch one ti choose depends solely on the status of the disease and to ascertain that a gud examination and history taking with face to face consultation is reqdNw a days vit d3 is also used in AD so also cyclosporine. there r numerous therapeutic modalities bt as I said treatment is alwyz individualised

FAQs

What is Pretac 0.1% Ointment used for?

Pretac 0.1% Ointment is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Pretac 0.1% Ointment acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.

What are the side effects of Pretac 0.1% Ointment?

Pretac 0.1% Ointment, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.

Is Pretac 0.1% Ointment ointment safe?

As compared to other immune-suppressing medicines, Pretac 0.1% Ointment has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.

Does Pretac 0.1% Ointment has abuse potential?

No, Pretac 0.1% Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.

Does Pretac 0.1% Ointment cause cancer?

Long-term use of Pretac 0.1% Ointment has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Pretac 0.1% Ointment ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Pretac 0.1% Ointment ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.

Is Pretac 0.1% Ointment a steroid?

No, Pretac 0.1% Ointment is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Pretac 0.1% Ointment is that it does not cause skin thinning (atrophy) or other steroid-related side effects.

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References

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
Tacrolimus monohydrate. Hurley, Berkshire: Leo Laboratories Limited; 2002 [revised 30 Jun. 2018]. [Accessed 17 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
Tacrolimus [Prescribing Information]. Dublin 12, Ireland: LEO Laboratories Ltd.; 2022. [Accessed 01 Aug. 2023]. (online) Available from:

Marketer details

Name: Carlton Dermatology

Address: 110, Industrial Area, Phase 2, Panchkula Haryana, Panchkula Industrial Area Phase 2, Panchkula - 134113 (Map)

Country of origin: India

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