Pnpl 40 Tablet is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and Zollinger-Ellison syndrome. It provides relief from the symptoms and promotes healing.

Pnpl 40 Tablet is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of painkillers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. You should keep on taking it as prescribed even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.

The most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, and stomach pain. These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it.

Uses of Pnpl Tablet

Acidity
Treatment of Heartburn
Gastroesophageal reflux disease (Acid reflux)
Peptic ulcer disease
Treatment of Zollinger-Ellison syndrome

Benefits of Pnpl Tablet

In Treatment of Heartburn

Heartburn and acid reflux happens when a muscle above your stomach relaxes too much and allows stomach contents and acid to come back up into your esophagus and mouth. Pnpl 40 Tablet belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You can increase the efficiency of the medicine by making certain lifestyle changes. These include avoiding foods that trigger the symptoms, eating smaller more frequent meals, losing weight if you are overweight.

In Treatment of Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Pnpl 40 Tablet By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.

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Side effects of Pnpl Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pnpl

Upper respiratory tract infection
Diarrhea
Flatulence
Headache
Nausea
Stomach pain
Vomiting
Dizziness

How to use Pnpl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pnpl 40 Tablet is to be taken empty stomach.

How Pnpl Tablet works

Pnpl 40 Tablet is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pnpl 40 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Pnpl 40 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Pnpl 40 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Pnpl 40 Tablet may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Pnpl 40 Tablet is safe to use in patients with kidney disease. No dose adjustment of Pnpl 40 Tablet is recommended.

Liver

CAUTION

Pnpl 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Pnpl 40 Tablet may be needed. Please consult your doctor.

What if you forget to take Pnpl Tablet?

If you miss a dose of Pnpl 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pnpl 40 Tablet

₹5.81/Tablet

Pantakind Tablet

Mankind Pharma Ltd

₹5.09/tablet

12% cheaper

Pantafol 40mg Tablet

Leeford Healthcare Ltd

₹4.74/tablet

18% cheaper

Panum 40 Tablet

J B Chemicals and Pharmaceuticals Ltd

₹3.23/tablet

44% cheaper

PAN 40 Tablet

Alkem Laboratories Ltd

₹12.33/tablet

112% costlier

Pantocid Tablet

Sun Pharmaceutical Industries Ltd

₹12.67/tablet

118% costlier

View all substitutes

Quick tips

Pnpl 40 Tablet should be taken 1 hour before a meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use of Pnpl 40 Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Do not stop taking medication without talking to your doctor.
Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Pnpl 40 Tablet should be taken 1 hour before a meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use of Pnpl 40 Tablet can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Fact Box

Chemical Class

Sulfinylbenzimidazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Proton-Pump Inhibitors

Interaction with drugs

Taking Pnpl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Erlotinib (Oral Route) Severe

Do not consume Erlotinib with Pantoprazole. Pantoprazole may reduce blood levels of Erlotinib.

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

View all drug interactions

Patient concerns

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often

Dr. Vijay Verma

ENT

it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination

Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen

Dr. Saurav Arora

Homeopathy

Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,

What is Pnpl 40 Tablet used for?

Pnpl 40 Tablet is used for the treatment of peptic ulcer disease, reflux esophagitis or gastroesophageal reflux disease (GERD). Pnpl 40 Tablet prevents acidity associated with use of painkillers. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms.

How long does it take for Pnpl 40 Tablet to work?

You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Pnpl 40 Tablet to work properly so you may still have some symptoms during this time.

Is a single dose of Pnpl 40 Tablet sufficient?

No, a single dose may not be sufficient. However, with only a few doses of Pnpl 40 Tablet you may get relief with the symptoms. Pnpl 40 Tablet is usually needed only for a short term or upto 2 weeks for heartburn, indigestion, acid reflux. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pnpl 40 Tablet may be prescribed for a long term duration as well. Please consult your doctor if you do not feel better even after taking Pnpl 40 Tablet regularly for 2 weeks as prescribed.

Is Pnpl 40 Tablet safe?

Yes, Pnpl 40 Tablet is relatively safe. Most of the people who take Pnpl 40 Tablet do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefits.

Can I take Pnpl 40 Tablet for a long term?

Pnpl 40 Tablet is usually prescribed for short-term use only. However, if the need arises, such as for treating peptic ulcer disease, ZE syndrome, etc. Pnpl 40 Tablet may be prescribed for a long-term duration as well. Long-term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Pnpl 40 Tablet as advised by your doctor and under their supervision.

What are the long term side effects of Pnpl 40 Tablet?

If Pnpl 40 Tablet is used for more than 3 months, certain long-term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky, or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections, and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally, you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas), or nerve problems such as numbness, tingling, and problem in walking.

What is the best time to take Pnpl 40 Tablet?

Usually, Pnpl 40 Tablet is taken once a day, first thing in the morning. If you take Pnpl 40 Tablet twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not to be chewed or crushed) and taken at least 1 hour before a meal with some water.

Can I stop taking Pnpl 40 Tablet if I feel better?

If you have been taking Pnpl 40 Tablet for a long time. Stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Pnpl 40 Tablet.

Does Pnpl 40 Tablet cause weight gain?

Although rare but long-term treatment with Pnpl 40 Tablet may cause weight gain. The reason could be the relief from reflux symptoms which could make you eat more. Consult your doctor for any weight-related concern.

Can I take alcohol with Pnpl 40 Tablet?

No, alcohol intake is not advised with Pnpl 40 Tablet. Alcohol itself does not affect the working of Pnpl 40 Tablet, but it can increase the acid production. This may further cause worsening of your symptoms.

Can I take antacids along with Pnpl 40 Tablet?

Yes, you can take antacids along with Pnpl 40 Tablet. Take it 2 hours before or after you take Pnpl 40 Tablet.

What dietary changes should I make to get relief from acidity?

Pnpl 40 Tablet is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee and cola. Alcohol intake should also be avoided as it may worsen your symptoms.

Are painkillers safe to take along with Pnpl 40 Tablet?

Yes, it is safe to take painkillers along with Pnpl 40 Tablet. Pnpl 40 Tablet prevents acidity and stomach ulcers associated with the intake of painkillers. Pnpl 40 Tablet is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.

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References

Pantoprazole. Konstanz, Germany: Wyeth Pharmaceutical; 2000 [revised Mar. 2012]. [Accessed on 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Pantoprazole. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Pantoprazole. [Updated 2022 May 15]. [Accessed 25 Jul. 2023] (online) Available from:

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