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Pioz-V Tablet is a medicine used to manage blood sugar levels in people with type 2 diabetes mellitus. It helps to improve insulin sensitivity, enhance insulin secretion, and prevent serious complications in people with diabetes.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Jan 2026 | 03:32 PM (IST)
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Pioz-V Tablet image
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Product introduction

Pioz-V Tablet may be used by itself or in combination with other medicines. It may be taken with or without food. However, take it regularly and at the same time each day to get maximum benefits from it. Your doctor will decide what dose is best for you, and this may change from time to time according to how well it is working. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled because if stopped without consulting the doctor, your blood sugar levels could rise and put you at risk of complications. Remember that this combination medicine is only part of a treatment program and your lifestyle habits also play a big part in controlling diabetes. Eat a healthy diet, do regular exercise, and reduce body weight as advised.


 


The most common side effects of this medicine include upper respiratory tract infection, headache, muscle pain, sore throat, runny nose, and fever amongst others. Let your doctor know if any of these side effects do not go away or get worse. They may be able to help by adjusting the dosage or by prescribing an alternate medicine.


 


You should not take Pioz-V Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or severe kidney or liver disease. Tell the doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions before taking this medicine as it may not be suitable for you. Pregnant or breastfeeding women are advised to consult their doctors before taking the medicine. The doctor may also advise regular checkups and tests to monitor your blood sugar levels, blood cell counts, and liver function after starting a treatment with this combination medicine.

Benefits of Pioz-V Tablet

Treatment of Type 2 diabetes mellitus
Pioz-V Tablet helps improve insulin sensitivity and increases insulin secretion. This dual action helps lower blood sugar levels effectively. Lowering blood sugar levels reduces the risk of serious complications that can be caused by diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. It also helps reduce the risk of heart disease. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Pioz-V Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pioz-V
  • Upper respiratory tract infection
  • Headache
  • Muscle pain
  • Sore throat
  • Runny nose
  • Fever
  • Itchy rash
  • Trembling
  • Joint pain
  • Constipation
  • Edema (swelling)
  • Diarrhea
  • Nausea
  • Heartburn

How to use Pioz-V Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pioz-V Tablet may be taken with or without food.

How Pioz-V Tablet works

Pioz-V Tablet is a combination of two antidiabetic medications. Pioglitazone primarily acts on muscle, fat, and liver cells to enhance their insulin response, making it easier for these cells to take up glucose from the bloodstream. It also reduces the production of glucose by the liver, which is a common problem in people with type 2 diabetes. Vildagliptin helps increase insulin secretion in response to meals while suppressing the release of glucagon, a hormone that raises blood sugar levels. Therefore, the combined effect of these medicines helps decrease blood glucose levels.

All substitutes for Pioz-V Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Pioz-V Tablet is commonly prescribed to treat type 2 diabetes and should not be taken by people with type 1 diabetes.
  • Follow the recommended dosage and timing. Do not make any changes to your medication regimen without consulting your doctor first.
  • Regularly monitor your blood sugar levels as recommended by your doctor.
  • Complement your medication with a healthy lifestyle. This includes eating a balanced diet, doing regular physical activity, maintaining a healthy weight, and avoiding excessive alcohol consumption.
  • Learn to recognize the symptoms of hypoglycemia (low blood sugar) and how to respond. It's important to be prepared to treat low blood sugar if it occurs.
  • Continue your regular follow-up appointments with your doctor.
  • Pioz-V Tablet is commonly prescribed to treat type 2 diabetes.
  • Follow the recommended dosage and timing. Do not make any changes to your medication regimen without consulting your doctor first.
  • Regularly monitor your blood sugar levels as recommended by your doctor.
  • Complement your medication with a healthy lifestyle. This includes a balanced diet, regular physical activity, maintaining a healthy weight, and avoiding excessive alcohol consumption.
  • Learn to recognize the symptoms of hypoglycemia (low blood sugar) and how to respond. Pioz-V Tablet can lower blood sugar levels, and it's important to be prepared to treat low blood sugar if it occurs.
  • Continue with regular follow-up appointments with your doctor. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pioz-V Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pioz-V Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pioz-V Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Pioz-V Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Pioz-V Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Pioz-V Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Pioz-V Tablet is a combination medication used to treat type 2 diabetes mellitus. It is prescribed to adults to help control their blood sugar levels, especially when diet, exercise, and a single antidiabetic medication are not effective enough.
The exact time Pioz-V Tablet takes to show improvement in your blood sugar level is not known. However, you can expect to notice lower random blood sugar levels in 3 to 4 weeks. A noticeable reduction in HbA1c (a measure of long-term blood sugar) can be seen after a few weeks of consistent use.
For many people with type 2 diabetes, effective oral medications like Pioz-V Tablet can help delay, or even prevent, the need for insulin injections by maintaining good blood sugar control. However, this should always be discussed with your doctor.
One of the key benefits of Pioz-V Tablet is that it has a low risk of causing hypoglycemia. Vildagliptin in Pioz-V Tablet works in a glucose-dependent manner, meaning it only stimulates insulin release when blood sugar levels are high, which makes it a safer option.
Pioz-V Tablet contains pioglitazone and vildagliptin. While pioglitazone on its own can sometimes cause weight gain, studies have shown that when combined with vildagliptin, there are no substantial changes in body weight. Your doctor will monitor your weight as part of your overall treatment plan.
Pioz-V Tablet is particularly beneficial for individuals with type 2 diabetes who have insulin resistance (where the body's cells do not respond well to insulin), and are not achieving their blood sugar targets with a single medication.
It is very important to inform your doctor if you have a history of heart failure, liver problems, or bladder cancer. Pioz-V Tablet can carry risks associated with these conditions, and your doctor will need to evaluate if this medication is safe for you.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: USV Private Limited
Address: Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pioz-V Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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