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Phoscan 50mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 14 Apr 2026 | 04:20 PM (IST)
Phoscan 50mg Tablet is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
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Phoscan 50mg Tablet is currently sold out
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Phoscan 50mg Tablet
Phoscan 50mg Tablet
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Cycloxan 50mg Tablet
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General Information

Contains

Cyclophosphamide (50mg)

Marketer

Enrico Pharmaceuticals

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Phoscan 50mg Tablet image
Phoscan 50mg Tablet image

Product introduction

Phoscan 50mg Tablet should be taken with food preferably in morning but at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Phoscan Tablet

Benefits of Phoscan Tablet

Cancer
Cancer occurs when abnormal cells grow uncontrollably in the body, potentially spreading to other organs. It can affect various tissues and organs, leading to serious health complications. Phoscan 50mg Tablet is used in the treatment of several types of cancers, including lymphomas, leukemia, breast cancer, and ovarian cancer. It works by slowing or stopping the growth of cancer cells, helping to shrink tumors and control disease progression. This contributes to prolonged survival and improved quality of life in patients undergoing cancer therapy.
Nephrotic syndrome
Nephrotic syndrome is a kidney condition characterized by excessive protein loss in the urine, leading to swelling, low protein levels in the blood, and increased cholesterol levels. It can result from autoimmune diseases or other kidney disorders. Phoscan 50mg Tablet is used in certain cases of nephrotic syndrome, particularly when the condition does not respond well to other treatments. It helps by suppressing abnormal immune activity that causes kidney damage, thus reducing protein loss, relieving swelling, and preserving kidney function.

Side effects of Phoscan Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Phoscan
  • Nausea
  • Infection
  • Diarrhea
  • Vomiting
  • Decreased white blood cell count (neutrophils)
  • Decreased white blood cell count (lymphocytes)
  • Myelosuppression
  • Cystitis
  • Microhematuria
  • Hair loss

How to use Phoscan Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Phoscan 50mg Tablet should be taken with or after food.

How Phoscan Tablet works

Phoscan 50mg Tablet is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

All substitutes for Phoscan 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Phoscan 50mg Tablet helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Phoscan 50mg Tablet if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.
  • Phoscan 50mg Tablet helps in the treatment of cancer.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Take it with food if you experience irritation of the stomach, preferably in the morning.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Phoscan 50mg Tablet if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Phoscan 50mg Tablet.
Pregnancy

Pregnancy

UNSAFE
Phoscan 50mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Phoscan 50mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Phoscan 50mg Tablet may cause side effects that could affect your ability to drive.
Phoscan 50mg Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney

Kidney

CAUTION
Phoscan 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Phoscan 50mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Phoscan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Pegfilgrastim (Injection Route)

Do not consume Pegfilgrastim from 24 hours before or 24 hours after taking Cyclophosphamide. Cyclophosphamide may reduce the efficacy of Pegfilgrastim.
Severe

Molgramostim (Injection Route)

Do not consume Cyclophosphamide from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Severe

Natalizumab (Injection Route)

Do not consume Natalizumab with Cyclophosphamide.
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Cyclophosphamide with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Cyclophosphamide may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Cyclophosphamide with Purified Vi Polysaccharide Typhoid Vaccine. If essential, please consult your doctor. Cyclophosphamide may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Frequently asked questions

Yes, Phoscan 50mg Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Phoscan 50mg Tablet.
No, there is no evidence that you need to avoid sun exposure while on Phoscan 50mg Tablet. Skin and nail discoloration are reported rarely with Phoscan 50mg Tablet.
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Phoscan 50mg Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Phoscan 50mg Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Yes, Phoscan 50mg Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Yes, Phoscan 50mg Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Phoscan 50mg Tablet for nephrotic syndrome has not been established.
Yes, Phoscan 50mg Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
Yes, Phoscan 50mg Tablet can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Phoscan 50mg Tablet.
No, there is no evidence that you need to avoid sun exposure while on Phoscan 50mg Tablet. Skin and nail discoloration are reported rarely with Phoscan 50mg Tablet.
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Phoscan 50mg Tablet is high in the urinary bladder. Other rare cancers that may occur with use of Phoscan 50mg Tablet include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Yes, Phoscan 50mg Tablet is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Yes, Phoscan 50mg Tablet can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Phoscan 50mg Tablet for nephrotic syndrome has not been established.
Yes, Phoscan 50mg Tablet may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Fact Box

Chemical Class

Nitrogen mustard compounds

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating Agents

References

  1. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:
  4. Cyclophosphamide monohydrate. Norfolk, UK: Baxter Healthcare Ltd.; 2004 [revised 9 Dec. 2016]. [Accessed 26 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Enrico Pharmaceuticals
Address: A2/9,site-iv, Industrial Area, Sahibabad, DELHI-NCR-201010

Vendor Details

Country of origin: India
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