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Writing in Sciences, PGCCL
Reviewed By
MD (Pharma), MBBS
Last updated on:
07 Jan 2019 | 04:13 PM (IST)
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Overview

Uses of Pgl-M Capsule

Pgl-M 75 Capsule is used in the treatment of neuropathic pain.

Pgl-M Capsule side effects

Common
  • Dizziness
  • Sleepiness
  • Tiredness
  • Uncoordinated body movements

How to use Pgl-M Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pgl-M 75 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Pgl-M Capsule works

Pgl-M 75 Capsule is a combination of five medicines: Benfotiamine, Folic Acid, Methylcobalamin/Mecobalamin, Pregabalin and Vitamin B6 (Pyridoxine). Benfotiamine and Folic Acid provide essential nutrients to the nerves. Methylcobalamin/Mecobalamin and Vitamin B6 (Pyridoxine) are forms of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Pgl-M Capsule related warnings

Alcohol
CAUTION
Pgl-M 75 Capsule may cause excessive drowsiness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Pgl-M 75 Capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Pgl-M 75 Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Pgl-M 75 Capsule may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Kidney
Pgl-M 75 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Pgl-M 75 Capsule may not be needed in these patients. Please consult your doctor.
Liver
Pgl-M 75 Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pgl-M 75 Capsule may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pgl-M 75 Capsule
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Patient Concerns

Questions Related to Pgl-M

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I suffered from brain stroke. How long can I use gabapentin 300 mg tablets ?
Dr. Anshul Varshney
General Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. This medicine is used to calm down the neuropathic pain. You may take it till you feel better. Later your doctor may reduce the dose and stop it.
I m suffering due to pain in left testis, so I visited pgimer Chandigarh in urology deptt. There I had gone for dopler ultrasound testis and its reports are normal Now whenever I lay down at bed I felt a smaal lump in testis,when I touchdown it, the pain radiates in whole left testis Now I m feeling pain sometimes in both tastis Is it a sign of early vericoseal Or something else Pls. Suggest
Dr. Pranay Gandhi
Sexologist
it is a neuropathic pain and it won't show any abnormality in USG. i am worried about the lump u r talking about. its better if u consult a surgeon, PGIMER UROLOGY is the best place to go for examination. if they say its normal, its normal. for pain take pregaba m 1 od
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FAQs

Q. What are the instructions for the storage and disposal of Pgl-M?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Pgl-M?

Pgl-M is a combination of five medicines: Pregabalin, Methylcobalamin, Folic acid, Benfotiamine and vitamin B6. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

Q. Can I stop taking Pgl-M when my pain is relieved?

No, you should not stop taking Pgl-M even if your pain is relieved. Continue to take it as advised by your doctor. If you stop taking Pgl-M suddenly, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the use of Pgl-M before you stop the medication completely.

Q. How to manage weight gain associated with the use of Pgl-M?

Pgl-M can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, eat fruits, vegetables, and low-calorie foods. Regular exercise will also help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Pgl-M cause sleepiness or drowsiness?

Yes, Pgl-M may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.

Q. Are there any serious side effects associated with the use of Pgl-M?

Serious side effects with Pgl-M are uncommon and rare. However, it may cause serious side effects like an allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Pgl-M and contact your doctor if you have any signs of these serious side effects. Signs of allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck, trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to sudden changes in mood, behaviors, thoughts, or feelings a these may be a symptom of suicidal thoughts.

Q. How long will Pgl-M take to act?

An initial benefit with Pgl-M may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may take even longer in some patients.

Q. What if I forget to take Pgl-M?

If you forget to take the scheduled dose of Pgl-M and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Q. What if I take too much of this drug by mistake?

In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteady when walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.

Q. Will a higher than the recommended dose of Pgl-M be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can I drink alcohol while taking Pgl-M?

No, do not drink alcohol while taking Pgl-M. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Pgl-M.

Q. How often should I see the doctor?

You may need to see your doctor regularly if you have started to take Pgl-M. However, consult your doctor if the recommended dosage does not relieve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Manufacturer/Marketer Address
Mission Research Laboratories (I) Pvt. Ltd., Plot No. 45, N.T.M, Sector – 26, Chandigarh 160019.
A licensed pharmacy from your nearest location will deliver Pgl-M 75 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
MRP
120
10 capsules in 1 strip
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