Perindosyl Plus 4mg/1.25mg Tablet

Prescription Required
Storage
Store below 30°C

Introduction

Perindosyl Plus 4mg/1.25mg Tablet is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke.

Perindosyl Plus 4mg/1.25mg Tablet should be taken on empty stomach, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

Nausea, taste change, diarrhea, and indigestion are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Let your doctor know about cough or throat irritation that does not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. If dizziness happens, rise slowly from sitting position or avoid driving.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function and the levels of salts such as potassium checked regularly to make sure that this medicine is working properly.

Uses of Perindosyl Plus Tablet

Benefits of Perindosyl Plus Tablet

In Hypertension (high blood pressure)

Perindosyl Plus 4mg/1.25mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Perindosyl Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Perindosyl Plus

  • Nausea
  • Diarrhea
  • Stomach pain
  • Constipation
  • Vomiting
  • Headache
  • Vertigo
  • Dizziness
  • Altered vision
  • Numbness
  • Ringing in ear
  • Breathlessness
  • Indigestion
  • Allergic reaction
  • Skin rash
  • Itching
  • Cramps
  • Fatigue

How to use Perindosyl Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perindosyl Plus 4mg/1.25mg Tablet is to be taken empty stomach.

How Perindosyl Plus Tablet works

Perindosyl Plus 4mg/1.25mg Tablet is a combination of two medicines: Perindopril and indapamide which lower blood pressure effectively. Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Indapamide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Safety advice

Alcohol
UNSAFE
Perindosyl Plus 4mg/1.25mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Perindosyl Plus 4mg/1.25mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Perindosyl Plus 4mg/1.25mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Perindosyl Plus 4mg/1.25mg Tablet may cause side effects which could affect your ability to drive.
Perindosyl Plus 4mg/1.25mg Tablet usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.
Kidney
CAUTION
Perindosyl Plus 4mg/1.25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Perindosyl Plus 4mg/1.25mg Tablet may be needed. Please consult your doctor.
Caution should be advised in patients with renal impairment.
Liver
CAUTION
Perindosyl Plus 4mg/1.25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Perindosyl Plus 4mg/1.25mg Tablet may be needed. Please consult your doctor.

What if you forget to take Perindosyl Plus Tablet?

If you miss a dose of Perindosyl Plus 4mg/1.25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Perindosyl Plus 4mg/1.25mg Tablet
₹17.0/Tablet
Perigard-D 4mg/1.25mg Tablet
Glenmark Pharmaceuticals Ltd
₹9.89/tablet
42% cheaper
Eviper D 4 mg/1.25 mg Tablet
Torrent Pharmaceuticals Ltd
₹10.9/tablet
36% cheaper
₹11.78/tablet
31% cheaper
₹17.3/tablet
2% costlier
Coversyl Plus Tablet
Serdia Pharmaceuticals India Pvt Ltd
₹19.25/tablet
13% costlier

Quick tips

  • You have been prescribed Perindosyl Plus 4mg/1.25mg Tablet for the treatment of high blood pressure.
  • It also lowers your risk of stroke and heart attack.
  • Perindosyl Plus 4mg/1.25mg Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform you doctor about any cough, or throat irritation that doesn't go away.
  • Perindosyl Plus 4mg/1.25mg Tablet may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
  • Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.
  • Do not take Perindosyl Plus 4mg/1.25mg Tablet if you’re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.

Fact Box

Habit Forming
No
Therapeutic Class
CARDIAC

Patient concerns

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I am a patient of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinal condition of high blood pressure. Please see a physician.
Some times I had lot of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Perindopril erbumine+Indapamide. Boucherville, (QC), Canada: Sandoz Canada Inc.; 2018. [Accessed 11 Apr. 2019] (online) Available from:External Link
  2. Perindopril arginine+indapamide. Wicklow, Ireland: Servier (Ireland) Industries Ltd.; 2018. [Accessed 11 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

“Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
MRP
170
Inclusive of all taxes
10 tablets in 1 strip
SOLD OUT
NOTIFY ME
Available substitutes
Available substitutes
Contains the same salt composition as
Perindosyl Plus 4mg/1.25mg Tablet
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