Pentas 400 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Pentas 400 Tablet is an antibiotic used to treat a variety of bacterial infections. It is used in infections of the throat, ear, nasal sinuses, respiratory tract, skin, and soft tissue, rheumatic fever, and sexually transmitted diseases like syphilis.

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Pentids 400 Tablet

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Pentas 400 Tablet

strip of 6 tablets

₹6.5

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Same composition

Pentids 400 Tablet

strip of 10 tablets

Penicillin G (400000IU)

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Pentas 400 Tablet may be taken with or without food. Take it in the dose and duration prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Common side effects of Pentas 400 Tablet include fever, chills, headache, exacerbation of cutaneous lesions, hyperventilation, vasodilation with flushing, and mild hypotension. If any of these side effects persist or worsen, discuss them with your doctor. They may be able to provide supportive treatments or adjust your dosage.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any similar type of medicine. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision. Let your doctor also know if you have preexisting medical conditions or if you are taking any other medications.

Uses of Pentas Tablet

Benefits of Pentas Tablet

Treatment of Bacterial infections
Pentas 400 Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It works by stopping the growth of the bacteria causing the infection. This medicine is given by a doctor or a nurse and should not be self-administered. It usually makes you feel better quite quickly. You must continue the treatment as prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Treatment of Syphilis
Syphilis is a serious bacterial infection that can affect multiple parts of the body. Pentas 400 Tablet works by killing the bacteria responsible for the disease, preventing it from spreading and causing long-term complications. Early treatment with Pentas 400 Tablet ensures a faster recovery and reduces the risk of serious health issues.

Prevention of Rheumatic fever
Rheumatic fever is an inflammatory disease caused by the bacteria streptococcus, that results usually die to inadequately treated throat infections or scarlet fever caused by the same microorganisms. Pentas 400 Tablet effectively relieves symptoms, controls inflammation and also prevents the disease from returning. If you are allergic to penicillin, tell your doctor before taking it, so you may be treated with some other alternate medicine. If you are using it for the first time, let your doctor know if you notice any signs of allergy such as rash, swelling or any other bothersome side effect.

Side effects of Pentas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentas

Fever
Chills
Muscle pain
Headache
Skin lesion
Fast heart rate
Hyperventilation (rapid breathing)
Vasodilation
Hypotension (low blood pressure)

How to use Pentas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentas 400 Tablet may be taken with or without food.

How Pentas Tablet works

Pentas 400 Tablet is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive.

All substitutes for Pentas 400 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Pentids 400 Tablet

by Abbott

₹2.27/tablet

110% costlier

Quick tips

Complete the full course of treatment. Do not stop taking Pentas 400 Tablet even if you feel better; stopping early may lead to antibiotic resistance.
Do not take with fruit juices, soft drinks, or acidic foods, as they may interfere with absorption.
Drink plenty of water and stay hydrated to help with drug absorption and prevent stomach upset.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pentas 400 Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Pentas 400 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

SAFE

Pentas 400 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Pentas 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pentas 400 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What should I discuss with my doctor before receiving Pentas 400 Tablet?

Before taking Pentas 400 Tablet, you should tell your doctor if you have ever had an allergic reaction to Pentas 400 Tablet or any similar medicine. Inform the doctor if you have any type of allergy, asthma, or breathing problems, heart disease, or kidney disease. Let your doctor know about all the medicines that you may be taking, as they may affect or be affected by Pentas 400 Tablet. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Pentas 400 Tablet.

I feel better now. Can I stop taking Pentas 400 Tablet?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved, but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Pentas 400 Tablet as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Does Pentas 400 Tablet treat the flu?

No, Pentas 400 Tablet does not treat viral infections like the flu or a common cold.

Can Pentas 400 Tablet cause an allergic reaction?

Yes. Pentas 400 Tablet may cause an allergic reaction, although it is rare. Get emergency medical help if you have any of the signs of an allergic reaction, such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

Fact Box

Chemical Class

Dipeptides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Narrow Spectrum Penicillins

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Rapid Plasma Reagin

References

Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1482-86.
Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 774.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1080-81.
Penicillin G [Prescribing Information]. Princeton, NJ: Sandoz Inc.; 2020. [Accessed 17 Mar. 2025] (online) Available from:
Penicillin G [Prescribing Information]. Auckland, New Zealand: Sandoz New Zealand Ltd.; 2023. [Accessed 17 Mar. 2025] (online) Available from:

User feedback

What are you using Pentas Tablet for?

Prevention of rheumatic fever

48%

Bacterial infections

26%

Others

17%

Syphilis

How much was the improvement?

Excellent

64%

Average

21%

Poor

15%

What were the side-effects while using Pentas 400 Tablet?

No Side Effect

100%

How do you take Pentas Tablet?

With food

57%

With or without food

43%

Please rate Pentas 400 Tablet on price

Not Expensive

75%

Expensive

17%

Average

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Pentas 400 Tablet

Save more with additional offers

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Pentas Tablet

Benefits of Pentas Tablet

Side effects of Pentas Tablet

How to use Pentas Tablet

How Pentas Tablet works

All substitutes for Pentas 400 Tablet

Pentids 400 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What should I discuss with my doctor before receiving Pentas 400 Tablet?

I feel better now. Can I stop taking Pentas 400 Tablet?

Does Pentas 400 Tablet treat the flu?

Can Pentas 400 Tablet cause an allergic reaction?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Rapid Plasma Reagin

References

User feedback

What are you using Pentas Tablet for?

How much was the improvement?

What were the side-effects while using Pentas 400 Tablet?

How do you take Pentas Tablet?

Please rate Pentas 400 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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