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Pentaglobin Injection is used to strengthen the body's natural immune system to lower the risk of infection in persons with weakened immune system. It is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Apr 2026 | 03:00 PM (IST)
₹38306 MRP ₹4443914% off 
 
 
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General Information

Contains

Human Normal Immunoglobulin (95%)

Marketer

Paviour Pharmaceuticals Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Pentaglobin Injection image
Pentaglobin Injection image

Product introduction

Pentaglobin Injection has been shown to be effective in preventing infections in bone marrow transplant patients more than 20 years of age in the first 100 days post-transplant. It is used in the treatment of patients where antibody-forming capacity is severely impaired thereby subjecting them to a greater risk of infections. Pentaglobin Injection gives you antibodies that your body is not making on its own so you can fight infections. Both children and adults can have this therapy. It is administered as an injection. Your doctor will monitor you for some time after the administration of Pentaglobin Injection to check for any side effects.

Pentaglobin Injection may sometimes cause side effects like jnjection site reactions such as swelling, redness, pain, induration, itching, bruising, and rash and flushing (sense of warmth in the face, ears, neck, and trunk), . If you get any of these, or other side effects, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects.

Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination. It is not known whether this medicine is completely safe during pregnancy or breastfeeding so please take advice from your doctor.

Uses of Pentaglobin Injection

  • Immunoglobulins deficiency

Benefits of Pentaglobin Injection

Immunoglobulins deficiency
Pentaglobin Injection strengthens or boost the immune system and lower the risk of infection in persons with a weakened immune system. It works by producing antibodies against foreign substances thereby fighting against infection. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenic purpura-ITP). This helps stop bleeding and promote the formation of blood clots.

Side effects of Pentaglobin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pentaglobin
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Injection site reactions (pain, swelling, redness)
  • Injection site soreness
  • Injection site bruising
  • Itching
  • Rash

How to use Pentaglobin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pentaglobin Injection works

Immune globulin belongs to class of agents called immunostimulants. It works by restoring abnormally low immunoglobulin G levels to the normal range to fight against infectious agents.

Quick tips

  • Pentaglobin Injection is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood.
  • It may be injected under the skin or given into a muscle.
  • Your doctor will monitor you for some time after administration of Pentaglobin Injection to check for any side effects.
  • Do not drive or do anything requiring concentration unless you know how Pentaglobin Injection affects you.
  • Inform your doctor if you have received any live vaccine (e.g. oral polio, MMR) in the last three months.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pentaglobin Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Pentaglobin Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Pentaglobin Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Pentaglobin Injection does not usually affect your ability to drive.
You may experience side effects (for example dizziness or nausea) during Pentaglobin Injection that might affect the ability to drive.
Kidney

Kidney

CAUTION
Pentaglobin Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Pentaglobin Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Frequently asked questions

Pentaglobin Injection can reduce the efficiency of some vaccines (like measles/mumps/rubella or chickenpox vaccines). So, inform your doctor that you are on Pentaglobin Injection before you get any vaccines. Let your doctor also know if you are pregnant, planning to get pregnant or if you are breastfeeding. Patients should be adequately hydrated before administration of<br>Pentaglobin Injection.
No, this only means that you are responding well to the treatment. Do not stop taking this medicine without consulting the doctor. If you stop the medication before completing the treatment then you would be putting yourself at risk as your body would no longer be able to fight infections. However, in case of doubt, you should always talk to your doctor.
Your symptoms may take 3-4 weeks to improve. This duration can vary depending on the disease you have and the way you respond to the treatment. If you are not sure, consult your doctor.
Yes, Pentaglobin Injection can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, diabetes and hypovolemia (a decrease in the volume of circulating blood) are at risk of developing kidney failure. Additionally, patients who are overweight, over 65 years of age and who are using medicines that can cause kidney damage are also at risk of developing kidney failure. Also, Pentaglobin Injection which has sucrose, fructose or maltose as an ingredient in it is more likely to cause kidney damage.
No, Pentaglobin Injection does not cause hair loss. If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if it bothers you.

Fact Box

Chemical Class

Immunoglobulins

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Immunoglobulin
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Paviour Pharmaceuticals Pvt Ltd
Address: 311 – 312, Suneja Tower – 1, District Centre, Janak Puri, New Delhi – 110058

Vendor Details

Country of origin: India
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