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MD (Pharmacology), MBBS
Last updated:
28 Jul 2020 | 01:47 PM (IST)
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Pentaglobin Injection

Prescription Required
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Overview

Introduction

Pentaglobin Injection is used to strengthen the body's natural immune system to lower the risk of infection in persons with weakened immune system. This is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections.

Pentaglobin Injection has been shown to be effective in bone marrow transplant patients > 20 years of age in the first 100 days post-transplant for the prevention of systemic and local infections. It is indicated in the treatment of primary immunodeficiency states in which severe impairment of antibody-forming capacity is there. This puts you at greater risk for infections. It gives you antibodies that your body is not making on its own so you can fight infections. Both children and adults can have this therapy. It is administered intravenously. Your doctor will monitor you for some time after the administration of Human Normal Immunoglobulin to check for any side effects.

Pentaglobin Injection may sometimes cause side effects like back pain, chills, flushing (sense of warmth in the face, ears, neck, and trunk), dizziness, headache, nausea, decreased blood pressure, and muscle pain. If you get any of these, or other side effects, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects.

Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination. It is not known whether this medicine is completely safe during pregnancy or breastfeeding so please take advice from your doctor.

Uses of Pentaglobin Injection

  • Immunoglobulins deficiency

Benefits of Pentaglobin Injection

In Immunoglobulins deficiency

Pentaglobin Injection strengthens or boost the immune system and lower the risk of infection in persons with a weakened immune system. It works by producing antibodies against foreign substances thereby fighting against infection. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenic purpura-ITP). This helps stop bleeding and promote the formation of blood clots.

Side effects of Pentaglobin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentaglobin

  • Back pain
  • Chills
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Dizziness
  • Headache
  • Nausea
  • Decreased blood pressure
  • Muscle pain
  • Slow heart rate
  • Wheezing

How to use Pentaglobin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pentaglobin Injection works

Immune globulin belongs to class of agents called immunostimulants. It works by producing antibodies against foreign substances thereby fighting against infection.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pentaglobin Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pentaglobin Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CAUTION
Pentaglobin Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Pentaglobin Injection may cause side effects which could affect your ability to drive.
You may experience side effects (for example dizziness or nausea) during Pentaglobin Injection that might affect the ability to drive.
Kidney
CAUTION
Pentaglobin Injection should be used with caution in patients with kidney disease. Dose adjustment of Pentaglobin Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pentaglobin Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pentaglobin Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Pentaglobin Injection?

If you miss a dose of Pentaglobin Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Pentaglobin Injection is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood.
  • It may be injected under the skin or given into a muscle.
  • Your doctor will monitor you for some time after administration of Pentaglobin Injection to check for any side effects.
  • Do not drive or do anything requiring concentration unless you know how Pentaglobin Injection affects you.
  • Inform your doctor if you have received any live vaccine (e.g. oral polio, MMR) in the last three months.

Fact Box

Chemical Class
Vaccines
Habit Forming
No

Patient Concerns

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For vitamin D deficiency is injection and tab both are necessary?
Dr. Pushkar Mani
Physician
only tab is enough
Deficiency of vitamin D, as per the report attached feeling very tiredness, joint pains
Dr. Akshat Goel
Orthopaedics
Take two shots of Injection Arachitol 6Lac IU at an interval of 2 weeksAlso take Cap Uprise-D3-60k every sunday
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Do you have any questions related to Pentaglobin Injection ?

User Feedback


FAQs

Q. What should I keep in mind while taking Pentaglobin?

Pentaglobin can reduce the efficiency of some vaccines (like measles/mumps/rubella or chickenpox vaccines). So, inform your doctor that you are on Pentaglobin before you get any vaccines. Also, let your doctor know if you are pregnant, planning to get pregnant or if you are breastfeeding.

Q. If I feel fine, does it mean that I can discontinue my treatment with Pentaglobin?

No, this only means that you are responding well to the treatment. Do not stop taking this medicine without consulting the doctor. If you stop the medication before completing the treatment then you would be putting yourself at risk as your body would no longer be able to fight infections. However, in case of doubt, you should always talk to your doctor.

Q. How long will it take for Pentaglobin to start working?

Your symptoms may take 3-4 weeks to improve. This duration can vary depending on the disease you have and the way you respond to the treatment. If you are not sure, consult your doctor.

Q. Can Pentaglobin cause kidney damage?

Yes, Pentaglobin can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, diabetes and hypovolemia (a decrease in the volume of circulating blood) are at risk of developing kidney failure. Additionally, patients who are overweight, over 65 years of age and who are using medicines that can cause kidney damage are also at risk of developing kidney failure. Also, Pentaglobin which has sucrose, fructose or maltose as an ingredient in it is more likely to cause kidney damage.

Q. Does Pentaglobin cause hair loss?

No, Pentaglobin does not cause hair loss. If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if it bothers you.
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. EMEA. Human Normal Immunoglobulin. [Accessed 04 Apr. 2019] (online) Available from:External Link
  2. Immune Globulin Intravenous (Human). Bern, Switzerland: CSL Behring AG; 2007 [revised Sep. 2017]. [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

311 – 312, Suneja Tower – 1, District Centre, Janak Puri, New Delhi – 110058
A licensed vendor partner from your nearest location will deliver Pentaglobin Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP5290  Get 15% OFF
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₹4496.5
10 ml in 1 vial
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