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Last updated on:
16 Oct 2019 | 01:31 PM (IST)
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Pemsafe 500 mg Injection


Introduction of Pemsafe Injection

Pemsafe 500 mg Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

Pemsafe 500 mg Injection is given as an injection by a qualified medical professional. It should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Doctor may advice for regular monitoring of blood cells while taking Pemsafe 500 mg Injection.

Women should use effective contraception method and avoid pregnancy during the treatment. It may cause side effects like vomiting, hair loss, anemia (low number of red blood cells), and loss of appetite. But, it is important to inform doctor if you notice any signs of infection such as fever, sore throat, severe rash or diarrhea.

Pemsafe Injection side effects

  • Nausea
  • Vomiting
  • Pharyngitis
  • Loss of appetite
  • Stomatitis (Inflammation of the mouth)
  • Hair loss
  • Low blood platelets
  • Rash
  • Fatigue
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Neuropathy

How to use Pemsafe Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pemsafe Injection works

Pemsafe 500 mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Pemsafe Injection related warnings

It is not known whether it is safe to consume alcohol with Pemsafe 500 mg Injection. Please consult your doctor.
Pemsafe 500 mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Pemsafe 500 mg Injection should be used with caution during breatfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Pemsafe 500 mg Injection may cause side effects which could affect your ability to drive.
Pemsafe 500 mg Injection may make you feel tired and this may affect your ability to drive.
Pemsafe 500 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pemsafe 500 mg Injection may be needed. Please consult your doctor.
Use of Pemsafe 500 mg Injection is not recommended in patients with moderate to severe kidney disease.
Pemsafe 500 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemsafe 500 mg Injection may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pemsafe 500 mg Injection
Pemgem 500mg Injection
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Pemcure 500mg Injection
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Pemmet 500 Injection
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Pexitaz 500mg Injection
Sun Pharmaceutical Industries Ltd
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Pemexar 500mg Injection
RPG Life Sciences Ltd
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Expert Advice

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Patient Concerns

Questions Related to Pemsafe

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Cancer Specialist
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
Good evening, my father is suffering from lung cancer naming malignant mesothelioma. The same type of cancer my grandmother have. They both died due to this cancer disease. I want to know that is this a heridatory type of cancer? Is there is any probability in future that I will suffer from this type of cancer. Actually is their any preventive type of measures that I can follow that will help me prevent in future from suffering from cancer. Is their any tests available to keep regular updates about the trace of the cancer,
Dr. Vijay Sharnangat
Cancer Specialist
Restrain from any addiction, have regular exercise, eat healthy food.It's not hereditary, please don't get afraid.
Do you have any questions related to Pemsafe 500 mg Injection?


Q. Is Pemsafe a vesicant?

No. Pemsafe is not a vesicant

Q. Is Pemsafe a chemotherapy/ cytotoxic?

Yes. Pemsafe is chemotherapy and a cytotoxic drug

Q. Is Pemsafe safe?

Pemsafe is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Does Pemsafe cause hair loss?

Yes. Pemsafe is a prescription chemotherapy medication and hair loss is one of the possible side effects.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
  3. Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:External Link
  4. Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Cytocare Formulations , Pvt. Ltd., 1st Floor, 70C Sadananda Road, Kolkata - 700026, West Bengal, India
Best Price
MRP13990  Get 20% OFF
1 Injection in 1 vial


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