Pemetrex 500mg Injection
Prescription Required
Product introduction
Pemetrex 500mg Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.
Pemetrex 500mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Pemetrex Injection
- Non-small cell lung cancer
- Malignant pleural mesothelioma
Benefits of Pemetrex Injection
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Pemetrex 500mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Malignant pleural mesothelioma
Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Pemetrex 500mg Injection is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.
Side effects of Pemetrex Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pemetrex
- Nausea
- Vomiting
- Sore throat
- Loss of appetite
- Stomatitis (Inflammation of the mouth)
- Hair loss
- Low blood platelets
- Rash
- Fatigue
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased white blood cell count (neutrophils)
- Neuropathy
How to use Pemetrex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pemetrex Injection works
Pemetrex 500mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Safety advice
Alcohol
SAFE
Consuming alcohol with Pemetrex 500mg Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Pemetrex 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CAUTION
Pemetrex 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Pemetrex 500mg Injection may cause side effects which could affect your ability to drive.
Pemetrex 500mg Injection may make you feel tired and this may affect your ability to drive.
Pemetrex 500mg Injection may make you feel tired and this may affect your ability to drive.
Kidney
CAUTION
Pemetrex 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pemetrex 500mg Injection may be needed. Please consult your doctor.
Use of Pemetrex 500mg Injection is not recommended in patients with moderate to severe kidney disease.
Use of Pemetrex 500mg Injection is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Pemetrex 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemetrex 500mg Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Pemetrex Injection?
If you miss a dose of Pemetrex 500mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Pemetrex 500mg Injection
₹2034/Injection
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Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Glutamic Aacid Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Interaction with drugs
Taking Pemetrex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Concurrent use may cause a decrease in the ability of the bone marrow to pr
Do not consume Pemetrexed from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marro
Do not consume Pemetrexed from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone
Do not consume Pemetrexed from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marro
Do not consume Natalizumab with Pemetrexed.
Concomitant use may increase the risk of opportunistic infections.
Patient concerns
FAQs
Is Pemetrex 500mg Injection a vesicant?
No. Pemetrex 500mg Injection is not a vesicant.
Is Pemetrex 500mg Injection safe?
Pemetrex 500mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Does Pemetrex 500mg Injection cause hair loss?
Yes. Pemetrex 500mg Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
- Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:
- Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: BDR Pharmaceuticals Internationals Pvt
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Country of origin: India
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₹2034
Inclusive of all taxes
MRP₹2544 20% OFF
1.0 Injection in 1 vial
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