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Pagenax Solution for Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Pagenax Solution for Injection is a medication used to treat wet age-related macular degeneration in adults. It works by targeting and blocking a protein called vascular endothelial growth factor (VEGF) that causes abnormal blood vessel growth in the eye. This way it helps slow down the disease and preserve vision.

Pagenax Solution for Injection is administered as an injection into the affected eye. It is to be administered by a doctor or trained nurse; do not self-administer this medicine at home. The dose and frequency will be determined based on the patient’s specific condition. It is important to stick to the treatment schedule and follow the doctor's instructions for maximum results.

Common side effects of Pagenax Solution for Injection include eye pain, reduced visual acuity, blurred vision, floaters, retinal bleeding, and increased intraocular pressure (pressure inside the eye). If you experience any of these side effects which do not go away or get worse, consult with your doctor.

Pagenax Solution for Injection is contraindicated in patients with hypersensitivity (allergy) to any of the components of this medicine. Additionally, it is important to inform the doctor if you have any pre-existing medical conditions or have undergone any surgery recently, especially those related to the eye, before starting the treatment with this medicine. You should also avoid using Pagenax Solution for Injection if there are signs of infection in the eye.

Uses of Pagenax Solution for Injection

Benefits of Pagenax Solution for Injection

In Treatment of Wet age-related macular degeneration

Pagenax Solution for Injection helps treat wet age-related macular degeneration (AMD) by blocking a protein called VEGF that is responsible for abnormal blood vessel growth in the eye. This medicine reduces the growth and leakage of these abnormal blood vessels, slowing down the progression of the disease and preventing further damage. This can lead to improved vision and overall preservation of visual function, which can greatly benefit the quality of life of individuals living with wet AMD.

Side effects of Pagenax Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pagenax

  • Retinal hemorrhage (bleeding)
  • Uveitis
  • Eye pain
  • Reduced visual acuity
  • Blurred vision
  • Increased intraocular pressure
  • Corneal abrasion
  • Vitreous floaters
  • Iridocyclitis
  • Iritis (inflammation of the middle layer of the eye)
  • Retinal vascular disease
  • Vitreous haemorrhage
  • Vitreous detachment
  • Cataract
  • Conjunctival hemorrhage
  • Punctate keratitis

How to use Pagenax Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Pagenax Solution for Injection works

Vascular endothelial growth factor (VEGF) is a protein that promotes the growth of new blood vessels. In certain eye diseases, abnormal blood vessels start growing under the retina, leading to fluid leakage, bleeding, and damage to the central part of the retina called the macula. This can result in severe vision loss and distortion of central vision. Pagenax Solution for Injection blocks the activity of the VEGF protein. By inhibiting VEGF, the medication reduces the growth and leakage of abnormal blood vessels in the retina.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pagenax Solution for Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pagenax Solution for Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pagenax Solution for Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pagenax Solution for Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Pagenax Solution for Injection is safe to use in patients with kidney disease. No dose adjustment of Pagenax Solution for Injection is recommended.
Liver
SAFE IF PRESCRIBED
Pagenax Solution for Injection is safe to use in patients with liver disease. No dose adjustment of Pagenax Solution for Injection is recommended.

What if you forget to take Pagenax Solution for Injection?

If you miss a dose of Pagenax Solution for Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Pagenax Solution for Injection is administered by a qualified ophthalmologist or retina specialist.
  • Inform your eye doctor immediately if you experience any signs of infection, such as redness, pain, or discharge from the eye.
  • If you experience symptoms of an allergic reaction, such as hives, itching, swelling, or difficulty breathing, seek immediate medical attention.
  • Inform your eye doctor if you have a history of glaucoma or elevated intraocular pressure (IOP), as this may influence treatment decisions.
  • Inform your eye doctor immediately if you notice any sudden changes in vision or experience flashes of light.
  • Inform your eye doctor if you experience eye pain, redness, or sensitivity to light.
  • Pagenax Solution for Injection is administered by a qualified ophthalmologist or retina specialist.
  • Inform your eye doctor immediately if you experience any signs of infection, such as redness, pain, or discharge from the eye.
  • If you experience symptoms of an allergic reaction, such as hives, itching, swelling, or difficulty breathing, seek immediate medical attention.
  • Inform your eye doctor if you have a history of glaucoma or elevated intraocular pressure (IOP), as this may influence treatment decisions.
  • Inform your eye doctor immediately if you notice any sudden changes in vision or experience flashes of light.
  • Inform your eye doctor if you experience eye pain, redness, or sensitivity to light.

Fact Box

Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
OPHTHAL
Action Class
Vascular endothelial growth factor (VEGF) inhibitor

Patient concerns

arrow
Macular degeneration in left eye
Dr. Richa Jain
Ophthalmology
Get Oct done. n visit
Sir, is surgery necessary in the initial stages of macular degeneration or it can be cured with medicines
Dr. Richa Jain
Ophthalmology
What kind of surgery. Macular degeneration can't be cured.Share pic of your prescription
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Brolucizumab [Summary of Product Characteristics]. Dublin 4, Ireland: Novartis Europharm Limited; 2022. [Accessed 28 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Switzerland

29123
Inclusive of all taxes
MRP32358.96  10% OFF
1.0 Solution for Injection in 1 vial
SOLD OUT
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