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P.P.F 400000IU Injection

Prescription Required
Salt Synonyms
Store below 30°C

Product introduction

P.P.F 400000IU Injection is an antibiotic used in the treatment of various bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissue, and sexually transmitted diseases like syphilis.

P.P.F 400000IU Injection is also used to prevent some infections such as rheumatic fever and infection of the heart valves (bacterial endocarditis) in people with preexisting heart disease. It is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. 

P.P.F 400000IU Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle. It is generally administered by a doctor or a nurse, do not self-administer this medicine at home. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

Benefits of P.P.F Injection

In Treatment of Bacterial infections

P.P.F 400000IU Injection is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It works by stopping the growth of the bacteria causing the infection. This medicine is given by a doctor or a nurse and should not be self-administered. It usually makes you feel better quite quickly. You must continue the treatment as prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

In Treatment of Syphilis

Syphilis is a bacterial infection usually spread by sexual contact. The disease starts as a painless sore, particularly on your genitals, rectum, or mouth. If diagnosed in the early stages, syphilis can be treated with the use of P.P.F 400000IU Injection, which is an antibiotic that kills the infection-causing bacteria and also stops the progression of the disease. It is given only by a doctor or nurse into a muscle. Follow the doctor’s instructions carefully to get maximum benefit.

In Prevention of Rheumatic fever

Rheumatic fever is an inflammatory disease caused by the bacteria streptococcus, that results usually from inadequately treated throat infections or scarlet fever caused by the same microorganisms. P.P.F 400000IU Injection effectively relieves symptoms, controls inflammation and also prevents the disease from returning. If you are allergic to penicillin, tell your doctor before taking it, so you may be treated with some other alternate medicine. If you are using it for the first time, let your doctor know if you notice any signs of allergy such as rash, swelling or any other bothersome side effect.

Side effects of P.P.F Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of P.P.F

  • Rash
  • Allergic reaction
  • Injection site reactions (pain, swelling, redness)

How to use P.P.F Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How P.P.F Injection works

P.P.F 400000IU Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Safety advice

Consuming alcohol with P.P.F 400000IU Injection does not cause any harmful side effects.
P.P.F 400000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
P.P.F 400000IU Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
P.P.F 400000IU Injection does not usually affect your ability to drive.
P.P.F 400000IU Injection should be used with caution in patients with kidney disease. Dose adjustment of P.P.F 400000IU Injection may be needed. Please consult your doctor.
P.P.F 400000IU Injection should be used with caution in patients with liver disease. Dose adjustment of P.P.F 400000IU Injection may be needed. Please consult your doctor.

What if you forget to take P.P.F Injection?

If you miss a dose of P.P.F 400000IU Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • You have been prescribed P.P.F 400000IU Injection for the treatment of bacterial infections.
  • It is given by an injection into a vein or muscle, or via a drip into a vein. 
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.

Fact Box

Chemical Class
Habit Forming
Therapeutic Class

Interaction with drugs

Taking P.P.F with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Altrom, Cenorol, Cgtrom
Brand(s): Mikasun, Vizocin, Gramika
Brand(s): Ciprix, Capreo, Capreotec
Brand(s): Begenta

Patient concerns

My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic
Dr. Gopal Bansilal Samdani
Antibiotics are required if bacterial infections. Consult child specialist
ASO Titre is bit higher than normal. Shall I have to be worried for that much
Dr. Priyanka Shekhar
General Practitioner
ASO titer determination can help distinguish beta-hemolytic Group A Streptococcal rheumatic fever from acute rheumatic diseases.Get done rheumatoid factor test

User feedback


Q. What should I discuss with my doctor before receiving P.P.F 400000IU Injection?

Before taking P.P.F 400000IU Injection, you should tell your doctor if you have ever had an allergic reaction to P.P.F 400000IU Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by P.P.F 400000IU Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking P.P.F 400000IU Injection.

Q. Why do P.P.F 400000IU Injection shots hurt so much?

P.P.F 400000IU Injection is injected deeply into the muscle, usually into the butt muscle, using a lot of fluid used to inject it. Moreover, it is injected slowly which makes it even more painful.

Q. How is P.P.F 400000IU Injection given?

P.P.F 400000IU Injection can be given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle. It is generally administered by a doctor or a nurse, or under the supervision of a doctor or a nurse. You should not self-administer this medicine at home.

Q. The solution looks discolored. Can I still use P.P.F 400000IU Injection?

No. You should not use P.P.F 400000IU Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is best if you discard the solution and go for another vial.

Q. I feel better now. Can I stop taking P.P.F 400000IU Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking P.P.F 400000IU Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Q. Does P.P.F 400000IU Injection treat the flu?

No. P.P.F 400000IU Injection does not treat a viral infection such as the flu or a common cold.

Q. Can P.P.F 400000IU Injection cause an allergic reaction?

Yes. P.P.F 400000IU Injection may cause an allergic reaction, although it is rare. Get emergency medical help if you have any of the signs of an allergic reaction, such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 774.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1080-81.
  3. ScienceDirect. Penicillin G/Benzylpenicillin. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Penicillin G/Benzylpenicillin. New York NY: Pfizer Inc; Oct. 2015. [Accessed 29 Mar. 2019] (online) Available from:External Link
  5. Benzyl Penicillin [Product Description]. [Accessed 15 Feb. 2024] (online) Available from: External Link
  6. Benzyl Penicillin Injection [Product Information]. [Accessed 15 Feb. 2024] (online) Available from: External Link

Marketer details

Name: Karnataka Antibiotics & Pharmaceuticals Ltd
Address: Dr. Rajkumar Road Rajajinagar, 1st Stage Bangalore- 560 010 India
Country of origin: India

Inclusive of all taxes
MRP6.18  8% OFF
1.0 ml in 1 vial
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