
P.Col Ear Drop
Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 19 Sep 2025 | 03:31 PM (IST)
P.Col Ear Drop is a combination medicine that is used to treat ear infections. It prevents the growth of the bacteria that cause infection in the ears. It also relieves the symptoms of inflammation such as redness, itchiness, and irritation.
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General Information
Contains
Chloramphenicol (NA)+ Prednisolone (NA)
Marketer
Optho Remedies Pvt Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
P.Col Ear Drop is to be used as per the instructions given in the label or as suggested by your doctor. Use it only on the affected ear. Use it regularly to get the most benefit. The course of the medicine should be completed even if you feel better. Wash your hands before administering the medicine. Do not use it more than the recommended dose.
Generally, this is a safe medicine. However, it may cause mild and temporary irritation in the ear. Consult your doctor if any side effects persist or worry you. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before using it, tell your doctor if you have an underlying disease or are taking medicines for any health condition. The medicines that are used externally usually do not get affected by other medicines, however, you should let your doctor know if you are taking any medicines to ensure safety. Ask your doctor for advice if you are pregnant or breastfeeding.
Generally, this is a safe medicine. However, it may cause mild and temporary irritation in the ear. Consult your doctor if any side effects persist or worry you. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before using it, tell your doctor if you have an underlying disease or are taking medicines for any health condition. The medicines that are used externally usually do not get affected by other medicines, however, you should let your doctor know if you are taking any medicines to ensure safety. Ask your doctor for advice if you are pregnant or breastfeeding.
Uses of P.Col Ear Drop
Benefits of P.Col Ear Drop
Treatment of Ear infection
P.Col Ear Drop is used to treat infections in the ear caused by bacteria. It stops the growth of bacteria causing infection and helps relieve pain, swelling, redness, itching, or irritation in the ear. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
P.Col Ear Drop is used to treat infections in the ear caused by bacteria. It stops the growth of bacteria causing infection and helps relieve pain, swelling, redness, itching, or irritation in the ear. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side effects of P.Col Ear Drop
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of P.Col
- Irritation of ear
How to use P.Col Ear Drop
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the ear without touching it. Gently squeeze the dropper and place the medicine inside ear.
How P.Col Ear Drop works
P.Col Ear Drop is a combination of two medicines: Chloramphenicol and Prednisolone. Chloramphenicol is an antibiotic which stops bacterial growth in the ear by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Prednisolone is a steroid. It blocks the production of certain chemical messengers (prostaglandins) that make the ear red, swollen and itchy.
Quick tips
- Do not touch the tip to any surface, or to your ear, to avoid contamination.
- Talk to your doctor if your symptoms haven't started to improve within two days of starting treatment, if they get worse during treatment or if you get another ear infection.
- Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the drop in these areas.
- Stop using the medicine and inform your doctor if you notice ear irritation, burning sensation or allergic reaction.Â
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of P.Col Ear Drop during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of P.Col Ear Drop during breastfeeding is not available. Please consult your doctor.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Frequently asked questions
Usually, P.Col Ear Drop starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop using P.Col Ear Drop and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Fact Box
Habit Forming
No
Therapeutic Class
OTOLOGICALS
References
- Chloramphenicol. Romford, Essex: Martindale Pharma; 1998 [revised 9 Jul. 2001]. [Accessed 29 Mar. 2019] (online) Available from:
- Prednisolone sodium phosphate. Jordbro, Sweden: RPH Pharmaceuticals AB; 1992 [revised 28 Nov. 2018]. [Date of Access] (online) Available from:
- ScienceDirect. Prednisolone. [Accessed 29 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Optho Remedies Pvt Ltd
Address: Optho Remedies Pvt.Ltd. 28, MNNIT Industrial Estate, Teliarganj, Allahabad. Uttar Pradesh, India PIN - 211004
Address: Optho Remedies Pvt.Ltd. 28, MNNIT Industrial Estate, Teliarganj, Allahabad. Uttar Pradesh, India PIN - 211004
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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