Oxosign Syrup

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 23 Dec 2025 | 10:59 PM (IST)

Oxosign Syrup is a combination medicine used in the treatment of acidity, stomach ulcer, and heartburn. It helps in relieving the symptoms of acidity and ulcers such as stomach pain or irritation. It also neutralizes excessive acid in the stomach and helps in the easy passage of gas.

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₹137 MRP ₹154.6911% off

Oxosign Syrup is currently sold out

Same composition alternative:

Sucnol O Syrup

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31% cheaper alternative available

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Oxosign Syrup

bottle of 100 ml Syrup

₹137

~~₹154.69~~

Same composition

Sucnol O Syrup

bottle of 200 ml Syrup

Sucralfate (1000mg) + Oxetacaine (20mg)

by Knoll Pharmaceuticals Ltd

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₹187

₹0.8 per ml

₹159

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General Information

Contains

Sucralfate (1000mg)+ Oxetacaine (20mg)

Marketer

Capcure Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Oxosign Syrup is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. Do not take it for more than the recommended duration as long-term administration may have harmful effects on the health.

The most common side effects are constipation, nausea, vomiting, dizziness, insomnia, and allergic reaction. These are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. To overcome constipation, you should add fiber-rich foods in your diet and stay hydrated. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Oxosign Syrup

Benefits of Oxosign Syrup

Treatment of Acidity
Acidity is a condition when your stomach produces more acid than is needed for the digestion of food. Oxosign Syrup helps treat acidity. Oxosign Syrup gives relief from burning sensation and stomach pain associated with acidity.

Treatment of Heartburn
Heartburn is a burning feeling in your chest caused by stomach acids travelling back up towards your throat and mouth. Oxosign Syrup works by reducing the amount of acid your stomach makes and relieves the burning sensation and pain associated with heartburn. You can also take control of heartburn with few lifestyle changes. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Avoid eating within 3-4 hours of going to bed.

Treatment of Stomach ulcers
Stomach ulcers are painful sores that develop in the inner lining of the stomach. Oxosign Syrup is used to treat stomach ulcers. Oxosign Syrup covers the damaged ulcer tissue in the stomach and protects it against stomach acid or further injury. This helps ulcers heal more quickly. Oxosign Syrup also gives relief from pain and discomfort in the stomach associated with stomach ulcers. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

Side effects of Oxosign Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Oxosign

Constipation
Nausea
Vomiting
Dizziness
Insomnia (difficulty in sleeping)
Allergic reaction

How to use Oxosign Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Oxosign Syrup is to be taken on an empty stomach.

How Oxosign Syrup works

Oxosign Syrup is a combination of two medicines: Sucralfate and Oxetacaine / Oxethazaine. Sucralfate is a medication to treat ulcers. It covers the damaged ulcer tissue in the stomach and protects it from acid or injury to facilitate healing. Oxetacaine / Oxethazaine is a local anesthetic whose numbing effect provides fast relief from pain caused due to ulcers or acidic injury in the stomach.

All substitutes for Oxosign Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Oxosign Syrup helps treat acidity, heartburn and stomach ulcers.
Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
Avoid drinking anything immediately after taking this medicine as that can reduce its effectiveness.
Do not take antacid medicines half an hour before or after taking this medicine.
It may cause constipation. Drink plenty of water and eat more high-fibre foods. Inform your doctor if it becomes severe or doesn’t go away.
It may take 4-6 weeks or more for the ulcers to heal completely. Do not stop taking the medicine until your doctor tells you to.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Oxosign Syrup.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Oxosign Syrup during pregnancy is not available. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Oxosign Syrup may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Oxosign Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Oxosign Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Oxosign Syrup in patients with liver disease.

Frequently asked questions

Why is Oxosign Syrup prescribed?

Oxosign Syrup is prescribed for the treatment of acidity, heartburn and stomach ulcers.

How should I take Oxosign Syrup?

Take Oxosign Syrup on an empty stomach, at least 1 hour before or 2 hours after a meal.

Can I drink water after taking Oxosign Syrup?

Avoid drinking anything immediately after taking Oxosign Syrup as that can reduce the effectiveness of this medicine.

Can the use of Oxosign Syrup cause constipation?

Yes, Oxosign Syrup contains Sucralfate, which can cause constipation. To prevent constipation, eat high-fiber foods like vegetables, fruits and cereals. Drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or take a short walk. Talk to your doctor about treating constipation if it persists for a long time.

Can I stop taking Oxosign Syrup when my symptoms are relieved?

No, take Oxosign Syrup for the full prescribed length of time even if you feel better. Do not stop taking this medication without consulting your doctor.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Helicobacter Pylori IgA

Helicobacter Pylori IgG

Helicobacter Pylori IgM

References

Hoogerwerf WA, Pasricha PJ. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 967-981.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1067-1101.
Wolfe MM, Lowe RC (Editors). Pocket Guide to Gastrointestinal Drugs. Hoboken, New Jersey: Wiley Blackwell; 2014.
Sucralfate. Bridgewater, New Jersey: Aptalis Pharma US; 2013. [Accessed 15 Apr. 2019] (online) Available from:
Avinash S, Amresh S, Anuradha S. Sucralfate - Oxetacain Suspension in Management of Persistent Gastroenteritis of Varied Origin. 2017;3(3):17-22. [Accessed 14 Aug. 2024] (online) Available from:
Leeford. Sucralfate & Oxetacaine [Product Information]. [Accessed 14 Aug. 2024] (online) Available from:
Sucralfate [Product Information]. Pharmaceutical Associates, Inc.; 2022 [Accessed 08 Nov. 2025] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Capcure Pharmaceuticals
Address: Plot No-537, Industrial Area, Industrial Area Mohali Phase 9, Sahibzada Ajit Singh Nagar, Punjab 160066

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Oxosign Syrup

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Oxosign Syrup

Benefits of Oxosign Syrup

Side effects of Oxosign Syrup

How to use Oxosign Syrup

How Oxosign Syrup works

All substitutes for Oxosign Syrup

Sucnol O Syrup

Scrat O Syrup

Zomsuk O Syrup

Sucragord O Syrup Sugar Free

Mucocoat O Syrup

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Why is Oxosign Syrup prescribed?

How should I take Oxosign Syrup?

Can I drink water after taking Oxosign Syrup?

Can the use of Oxosign Syrup cause constipation?

Can I stop taking Oxosign Syrup when my symptoms are relieved?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Helicobacter Pylori IgA

Helicobacter Pylori IgG

Helicobacter Pylori IgM

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests