Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

24 Nov 2025 | 12:22 PM (IST)

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One Cold N Flu Total Tablet

Prescription Required

Marketer

Enrich One Well Being Pvt. Ltd.

SALT COMPOSITION

Aceclofenac (100mg) + Paracetamol (325mg) + Cetirizine (10mg) + Phenylephrine (5mg) + Caffeine (25mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

One Cold N Flu Total Tablet is a medication that helps alleviate the common cold symptoms. It relieves a runny nose, watery eyes, sneezing, and nasal congestion or stuffiness. Furthermore, it inhibits the release of certain chemicals that cause inflammation, pain, and fever associated with colds.

Take One Cold N Flu Total Tablet in the dose and duration as prescribed by the doctor. It may be taken with or without food. Take it regularly as long as it is required to get maximum benefits. Keep taking the medicine even if your symptoms disappear until you complete the dose. Do not stop taking the medicine suddenly unless the doctor tells you it is alright to stop.

Use of this medicine may cause nausea, vomiting, stomach pain, heartburn, and restlessness in some people. Let your doctor know if any of these side effects bother you. Before you take this medicine, let your doctor know about any other medicines you take. You should also tell your doctor if you have any problems with your heart, liver, or kidneys. Pregnant and breastfeeding women should consult their doctors first before taking this medicine.

Uses of One Cold N Flu Total Tablet

Treatment of Common cold

Benefits of One Cold N Flu Total Tablet

In Treatment of Common cold

One Cold N Flu Total Tablet is a combination medicine that effectively relieves symptoms of the common cold, such as a blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier.

One Cold N Flu Total Tablet is safe and effective. It usually starts to work within a few minutes, and the effects can last up to several hours. Take it as prescribed by your doctor, and do not stop using it unless you are advised otherwise.

Side effects of One Cold N Flu Total Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of One Cold N Flu Total

Heartburn
Nausea
Vomiting
Stomach pain
Restlessness

How to use One Cold N Flu Total Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. One Cold N Flu Total Tablet may be taken with or without food.

How One Cold N Flu Total Tablet works

One Cold N Flu Total Tablet combines five medicines: Aceclofenac, Paracetamol, Cetirizine, Phenylephrine, and Caffeine, which help treat common cold symptoms. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever. Cetirizine is an antihistamine medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body. Phenylephrine is a decongestant that narrows the small blood vessels, relieving congestion or stuffiness in the nose. Caffeine is a stimulant that decreases sleepiness caused by Cetirizine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with One Cold N Flu Total Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of One Cold N Flu Total Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of One Cold N Flu Total Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether One Cold N Flu Total Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of One Cold N Flu Total Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of One Cold N Flu Total Tablet in patients with liver disease.

What if you forget to take One Cold N Flu Total Tablet?

If you miss a dose of One Cold N Flu Total Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

One Cold N Flu Total Tablet

₹5.65/Tablet

Diecold Plus Tablet

Leeford Healthcare Ltd

₹4.21/tablet

25% cheaper

Criticold Advance Tablet

Leeford Healthcare Ltd

₹4.37/tablet

23% cheaper

Wincold Total Tablet

WINGS PHARMACEUTICALS PVT. LTD.

₹10.2/tablet

81% costlier

Cetisfy Total Tablet

Mestra Pharma Pvt Ltd

₹13.5/tablet

139% costlier

Aclopass Cold Tablet

Yuventis Lifesciences

₹8.01/tablet

42% costlier

Quick tips

One Cold N Flu Total Tablet is used to relieve the common cold symptoms.
It can make you restless, so don't take it too close to bedtime.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough and cold) without first asking your doctor.
Stick to simple meals and avoid fatty or spicy foods to prevent nausea after taking this medicine.
To feel better during the common cold, drink plenty of fluids, especially warm water, soup, etc.

Fact Box

Habit Forming

Therapeutic Class

RESPIRATORY

Patient concerns

I got hurt on my right hand ring finger a month before. It is still pains when pressure exerted. But it would be remaining pain less at the rest of the time.

Dr. Mehtab Baig

Orthopaedic Physiotherapy

One minute cold water and one minute hot water

I am having cold and flu and fever too from 2 days

Dr. Sunil Sekhri

Diabetology

Many a times it is viral infection. Take Tab Pacimol one tab SOS. Tab Lecope one tab once a day x 3 days. if no improvement get yourself examined

Suffering from cold since one month Tablet - Solvincold used but fruit less

Dr. Gladson Guddappa Uchil

ENT

PATIENT chemist is not a doctor, just a salesman! Please use this app to find and meet a good ENT Specialist in your city to examine you & do the needful. If you are able to make it to Bangalore, I would be very happy to help you out myself. My clinic Healthcare@Basaveshwaranagar is easily navigable on Google Maps.

Pain in right hand wrist since 4 weeks. Pain is felt when rotating / twisting wrist or lifting weights. Pain started after playing cricket after many years. Not physically active. As per x-ray report, swelling in soft tissue. No swelling visible from outside.

Dr. Mehtab Baig

Orthopaedic Physiotherapy

One minute cold water and 1 minute hot water for 10 times twice a dayDip hot water and just in cold water

What is One Cold N Flu Total Tablet used for?

One Cold N Flu Total Tablet is used to provide relief from cold and flu symptoms, including body pain, fever, runny nose, nasal congestion, sneezing, and headache. It combines pain relief with allergy and decongestant effects in one medicine.

Can One Cold N Flu Total Tablet help during seasonal allergies with body aches?

One Cold N Flu Total Tablet is particularly effective when you have allergic rhinitis combined with body pain or headache, as it addresses both allergic symptoms and pain simultaneously in one medicine.

Will One Cold N Flu Total Tablet make me drowsy or increase alertness?

While cetirizine in One Cold N Flu Total Tablet can cause mild drowsiness in some people, the caffeine in this medicine helps counteract drowsiness and keeps you more alert, making it suitable for daytime use with caution.

How quickly does One Cold N Flu Total Tablet start working after taking it?

You may start experiencing relief from pain and congestion within 1 hour after taking One Cold N Flu Total Tablet, with peak effects occurring within 1 to 2 hours for most symptoms.

Can I use One Cold N Flu Total Tablet for a severe sinus headache with a blocked nose?

One Cold N Flu Total Tablet is excellent for sinus‑related pain and congestion, as it unblocks nasal passages and reduces sinus pain and inflammation.

Should I avoid One Cold N Flu Total Tablet if I have high blood pressure?

You should consult your doctor first because phenylephrine and caffeine present in One Cold N Flu Total Tablet can raise blood pressure and may also affect cardiovascular function, requiring medical guidance for hypertensive patients.

Will One Cold N Flu Total Tablet help with fever caused by viral infections?

Yes. The paracetamol component in One Cold N Flu Total Tablet effectively reduces fever, while other medicines in One Cold N Flu Total Tablet manage associated symptoms like body ache, congestion, and sneezing common in viral infections.

Can I drink coffee or tea while taking One Cold N Flu Total Tablet?

Limit caffeine intake from other sources, as One Cold N Flu Total Tablet already contains caffeine, and excessive caffeine can cause jitteriness, rapid heartbeat, anxiety, or sleep disturbances.

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