
Ofspan 200mg Infusion
Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Ofspan 200mg Infusion is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues, and lungs (pneumonia). It cures the infection by stopping further growth of the causative microorganisms.
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General Information
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Product introduction
Ofspan 200mg Infusion is given as an injection into a vein (intravenous), in cases where oral administration is not possible, such as in hospitalized or unconscious patients. It is administered by a healthcare professional. Kindly do not self-administer. Avoid skipping any doses and finish the full course of treatment even if you feel better.
Some people may have nausea, headache, dizziness, and vomiting as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. These are usually temporary and resolve on their own, but please consult your doctor if these side effects persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue, or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.
Some people may have nausea, headache, dizziness, and vomiting as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. These are usually temporary and resolve on their own, but please consult your doctor if these side effects persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue, or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.
Uses of Ofspan Infusion
Benefits of Ofspan Infusion
Treatment of Bacterial infections
Ofspan 200mg Infusion is an antibiotic medicine that can be used to treat many different infections caused by bacteria. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.
Ofspan 200mg Infusion is an antibiotic medicine that can be used to treat many different infections caused by bacteria. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.
Side effects of Ofspan Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ofspan
- Nausea
- Headache
- Dizziness
- Itching
- Insomnia (difficulty in sleeping)
- Rash
- Genital itching
- Vaginal inflammation
- Phlebitis
- Injection site reactions (pain, swelling, redness)
How to use Ofspan Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Ofspan Infusion works
Ofspan 200mg Infusion is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
All substitutes for Ofspan 200mg Infusion
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Your doctor has prescribed Ofspan 200mg Infusion to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Ofspan 200mg Infusion and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Your doctor has prescribed Ofspan 200mg Infusion to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Ofspan 200mg Infusion and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Ofspan 200mg Infusion.

Pregnancy
CONSULT YOUR DOCTOR
Ofspan 200mg Infusion is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CAUTION
Ofspan 200mg Infusion should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Ofspan 200mg Infusion may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Ofspan 200mg Infusion should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Ofspan 200mg Infusion should be used with caution in patients with liver disease. Dose adjustment may be needed.
Interaction with drugs
Taking Ofspan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Cholera Vaccine (Inactivated) (Oral Route)
Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Ofloxacin. Please consult your doctor. Ofloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe
Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)
Ofloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Ofloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Moderate
Aceclofenac (Oral Route)
Do not consume Ofloxacin with Aceclofenac. If concurrent use is essential, watch out for convulsions and seizures and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations.
Moderate
Aceclofenac (Injection Route)
Do not consume Ofloxacin with Aceclofenac. If concurrent use is essential, watch out for convulsions and seizures and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations.
Moderate
Aceclofenac (Oral Route)
Do not consume Ofloxacin with Aceclofenac. If concurrent use is essential, watch out for convulsions and seizures and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations.
Frequently asked questions
Yes, the use of Ofspan 200mg Infusion can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
No, do not stop taking Ofspan 200mg Infusion and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Yes, use of Ofspan 200mg Infusion is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Ofspan 200mg Infusion. Inform your doctor if you feel any kind of muscle pain while using this medicine.
Fact Box
Chemical Class
Quinoline carboxylic acids
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1011-13.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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Address: 208 - S.F.,DEV ARC MALL COMMERCIAL SHOPPING CENTER, NR. ISCON CHAR RASTA, S.G.HIGHWAY, AHMEDABAD - 380015
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