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Composition for NOVEFOS


food interaction for NOVEFOS

alcohol interaction for NOVEFOS

pregnancy interaction for NOVEFOS

lactation interaction for NOVEFOS

It is better to take Novefos tablet empty stomach (1 hour before food or 2 hours after food).
Interaction with alcohol is unknown. Please consult your doctor.
Novefos tablet is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Novefos tablet is probably safe to use during breastfeeding. Please consult your doctor.




Novefos tablet is used for treatment of urinary tract infections and cystitis (infection of urinary bladder).

How it works

Novefos tablet is a phosphoenolpyruvate analogue produced by Streptomyces that irreversibly inhibits enolpyruvate transferase (MurA), which prevents the formation of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall.

Common side effects

Back pain, Diarrhoea, Dizziness, Pain during periods, Headache, Indigestion, Loss of appetite, Nausea, Running nose, Sore throat, Stomach upset, Vaginal itching, Vomiting, Fatigue


No substitutes found

Expert advice for NOVEFOS

  • Only one dose of fosfomycin is needed to treat your UTI. Once taken, the medicine will continue to fight the infection.
  • The medicine is in powder form that must be mixed with water before using. Do not mix it with hot water and never swallow the medicine in its dry form.
  • If you are prescribed with tetracycline, take it at least 2 hours before or after you take fosfomycin.
  • Discuss with your doctor if you have diarrhea or any kidney disease.
  • Do not drive or operate machinery as fosfomycin may make you dizzy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for NOVEFOS


Q. Is Fosfomycin a macrolide/sulfa drug/penicillin?
Fosfomycin is not macrolide/sulfa drug/penicillin. It is phosphonic acid derivative antibiotic.
Q. Can you take Fosfomycin with penicillin allergy/ does fosfomycin contain penicillin?
Fosfomycon does not contain penicillin and it can be taken with penicillin allergy.
Q. Does fosfomycin cover pseudomonas/ klebsiella/ proteus/ group b strep?
Fosfomycin works against pseudomonas, klebsiella and proteus but not against group b strep.


Content on this page was last updated on 15 September, 2016, by Dr. Varun Gupta (MD Pharmacology)