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MRP: Rs. 19.37 for 1 strip(s) (10 capsules each)
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Composition for NORSTREP

Norfloxacin(200 mg),Loperamide(2 mg)

food interaction for NORSTREP

alcohol interaction for NORSTREP

pregnancy interaction for NORSTREP

lactation interaction for NORSTREP

There is no data available. Please consult doctor before consuming the drug.
Norstrep 200mg/2mg capsule may cause excessive drowsiness and calmness with alcohol.
Norstrep 200mg/2mg capsule may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Norfloxacin(200 mg)


Norfloxacin is used in the treatment of adults with urinary tract infections, both uncomplicated (cystitis) and complicated urinary tract infections, sexually transmitted diseases (gonorrhea), genital infection, prostate infection (prostatitis), infections of the stomach or intestines (travelers’ diarrhea) and eye infection. It acts by inhibiting bacterial deoxyribonucleic acid synthesis and thus, killing the bacteria.

How it works

Norfloxacin belongs to class of drugs called flouroquinolone antibiotics. Norfloxacin inhibits bacterial reproduction by inhibiting DNA formation, thereby killing the bacteria.

Common side effects

Decreased urination, Facial swelling, Allergic reaction, Lip swelling, Skin rash, Itching, Urticaria, Shortness of breath, Anxiety, Muscle pain, Joint pain, Bruise, Bleeding, Blisters on skin, Convulsion, Dark colored urine, Dizziness, Diarrhoea, Headache, Hoarseness of voice, Loss of consciousness, Fainting, Restlessness, Stomach cramp, Tachycardia, Tremor, Uncoordinated body movements, Vomiting, Abdominal pain, Yellow discoloration of skin, Yellow discoloration of eye, Weakness, Fever, Confusion, Hallucination, Heartburn, Nausea
Loperamide(2 mg)


Loperamide is used for the treatment of diarrhea (loose stools).

How it works

Loperamide belongs to a category of drugs called as anti-diarrheal used to treat diarrhea. It acts by slowing down the movement of an overactive bowel, which helps in absorption of water and salts from the body that are usually lost in diarrhea.

Common side effects

Gastrointestinal discomfort, Constipation, Dizziness, Drowsiness, Dry mouth, Fatigue, Stomach pain, Vomiting


No substitutes found

Expert advice for NORSTREP

  • Avoid  norfloxacin if you have  known history of muscle weakness (myasthenia gravis). It may further increase the muscle weakness.
  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate -may increase nervousness, sleeplessness, heart pounding, and anxiety.
  • Drink plenty of water or other fluids every day while you are taking norfloxacin.
  • Do not start or continue the norfloxacin and consult your doctor if you have allergies to medicines, foods, or other substances.
  • Avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Norfloxacin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, consult your doctor.
  • Take norfloxacin at least one hour before or at least two hours after taking antacids (aluminum or magnesium hydroxide), didanosine, sucralfate, supplements or multivitamins that contain iron or zinc, meal or ingestion of milk and/or other dairy products. 
  • Norfloxacin can cause dizziness and light-headedness and, therefore, caution has to be taken before operating an automobile or machinery or engaging in activities requiring mental alertness and coordination.
  • Norfloxacin is associated with an increased risk of tendinitis and tendon rupture. it should be used carefully in patients over 60 years of age, in patients taking steroids corticosteroid drugs, in patients with kidney, heart or lung transplants to minimize this risk.

Frequently asked questions for NORSTREP


Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 same as ciprofloxacin?
No, however they belong to same class of medication called as fluoroquinolones and act by same mechanism but differ in absorption, metabolism and excretion.
Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 same as penicillin/broad spectrum antibiotic?
No, they belong to same class of medication called as fluoroquinolones and they act by different mechanism.
 Q. Is norfloxacin/ norflox tz/ norflox 400/ norilet/ norilet 400 used for treatment of diarrhea and UTI?
Yes, however it depends on microorganism involved and effectiveness. Always consult your doctor on this regards.
Q. Is norfloxacin sulfa based / a penicillin/ an antibiotic?
No. Norfloxacin belong to a different group of antibiotics called fluoroquinolones. It does not contain penicillin or sulpha.


Q. Is Loperamide safe?
Loperamide is relatively safe if used as recommended. In case of any side effects, consult your doctor.
Q. What is loperamide/Imodium/Eldoper used for?
Loperamide/Imodium/Eldoper is used for treating short-term or long-term diarrhea, with or without any associated disease.

Q. Can it be used for IBS?
 It may be used in few cases of IBS but please consult your doctor before its use.
Q. Can I take loperamide with antibiotics, paracetamol, ibuprofen, omeprazole, ciprofloxacin, desmopressin, ritonavir, quinidine or cotrimoxazole?
Loperamide may be taken simultaneously with antibiotics, paracetamol, ibuprofen, omiprazole or ciprofloxacin. Loperamide might interact with desmopressin, ritonavir, quinidine or cotrimoxazole. Please consult your doctor before use.
Q. Does loperamide help in opiate withdrawal?
Loperamide is used in higher doses as a part of opiate withdrawal process. However, do consult your doctor regarding the same.
Q. Is loperamide addictive?
No. Loperamide is a safe and non-addictive anti-diarrheal drug.

Q. Is it banned or available as over-the-counter drug?
 It is not banned but available over the counter in India.
Q. Can loperamide/ Impodium be used for stomach cramps, nausea, stomach flu, rota virus diarrhea and gas?
Loperamide may benefit few cases of stomach cramps or nausea associated with diarrhea. It is sometimes used for stomach flu, rota virus diarrhea. It is not used for gas. Please consult your doctor before taking the drug.


Content on this page was last updated on 03 June, 2014, by Dr. Varun Gupta (MD Pharmacology)