Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Interaction with drugs
Patient concerns
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Sachin Gupta

MD Pharmacology, MBBS

Last updated

14 Nov 2025 | 04:52 PM (IST)

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Node 50 Injection

Prescription Required

Marketer

Halden Healthcare & Research Pvt Ltd

SALT COMPOSITION

Nandrolone Decanoate (50mg)

Storage

Store below 25°C

View available alternative with same salt composition

Product introduction

Node 50 Injection is a medicine used in the treatment of osteoporosis in post-menopausal women, a certain type of anemia, and breast cancer. It works by helping build and strengthen body tissues, including bones and muscles, and supports red blood cell production, which makes it beneficial in these conditions.

Node 50 Injection is generally given by a healthcare professional. You should not self-administer this medicine at home. Your doctor will decide the dose and how often you should take them. You should take it regularly to get the most benefit from it. Do not stop using the medicine even if you feel better unless the doctor tells you so.

Using this medicine may cause a few common side effects such as pain at the injection site, hypertension, acne, itching, nausea, abnormal liver function & increased or decreased sexual desire. Let your doctor know if any of these side effects bother you.

Before using this medicine, inform your doctor if you have any liver or kidney problems. You should also tell your doctor all the other medicines you are taking. Pregnant and breastfeeding mothers should consult with their doctors before using the medicine.

Uses of Node Injection

Benefits of Node Injection

In Post menopausal osteoporosis

Node 50 Injection helps strengthen bones and reduce the risk of fractures in women with postmenopausal osteoporosis. It supports bone density and may improve overall bone health, especially in those who are at high risk of bone loss after menopause. With regular use as advised by a doctor, it can help maintain mobility, reduce bone pain, and improve quality of life.

In Breast cancer

Node 50 Injection is used as part of supportive care in advanced breast cancer. It can help improve strength, maintain muscle mass, and support overall health, especially in patients experiencing weight loss or fatigue. Its use is determined by the doctor based on the individual’s condition and treatment goals.

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Side effects of Node Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Node

Nausea
Acne
Injection site pain
Altered sexual function

How to use Node Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Node Injection works

Node 50 Injection is an anabolic steroid that works by promoting the growth and repair of body tissues. It improves protein synthesis and increases calcium retention in bones, which helps strengthen bone density in postmenopausal osteoporosis. It also stimulates the production of red blood cells in the bone marrow, making it effective in treating certain types of anemia. In breast cancer, Node 50 Injection may help improve strength, support weight maintenance, and counteract muscle loss, particularly in advanced stages where patients experience fatigue and physical decline.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Node 50 Injection. Please consult your doctor.

Pregnancy

UNSAFE

Node 50 Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Node 50 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Node 50 Injection does not usually affect your ability to drive.

Kidney

CAUTION

Node 50 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Node 50 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

What if you forget to take Node Injection?

If you miss a dose of Node 50 Injection, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

You have been prescribed Node 50 Injection for the treatment of osteoporosis in women after menopause, anemia, and breast cancer.
It is given as an injection into muscle of upper arm or leg by your doctor.
Inform your doctor if you develop male characteristics such as hoarseness, increased hair growth, acne and increased sex drive.
Do not take Node 50 Injection if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Chemical Class

Steroid esters

Habit Forming

Therapeutic Class

HORMONES

Action Class

Anabolic Steroids

Interaction with drugs

Taking Node with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Ciclosporin (Injection Route) Severe

Do not consume Ciclosporin with Nandrolone Decanoate. If concurrent use is essential, your doctor may monitor your liver function frequently. Concurrent use may cause liver damage... More

Ciclosporin (Oral Route) Severe

Do not consume Ciclosporin with Nandrolone Decanoate. If concurrent use is essential, your doctor may monitor your liver function frequently. Concurrent use may cause liver damage... More

Metformin (Oral Route) Moderate

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. If taken together, Nandrolone Decanoate may di... More

Voglibose (Oral Route) Moderate

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. If taken together, Nandrolone Decanoate may di... More

Glimepiride (Oral Route) Moderate

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. If taken together, Nandrolone Decanoate may di... More

View all drug interactions

Patient concerns

Cancer treatment for stage 3 or more from ureter and lymph node

Dr. Aanchal Maheshwari

Ayurveda

Although stage 3 is hard to treat, but case has to be seen in person before starting the treatment

noticed one sowelling at left suprascapular region six month back without any other complication. Done FNAC of the same, report- reactive hyperplasia of lymph node. Doctor advised to take clavam650 thrice a day. No improvement. Done usg twice within a fortnight. Newer report(attached) says reactive lymphodenopathy of axilla and suprascapular nodes with normal vascularity and cortex thickness 7 mm. Maximum size of nodes of left axilla being 3x.9 cm. again the new doctor of breach candy hospital advised cifram 500 x7 b.d. Now I feel occational pain in all above areas and both groin too. Please kindly suggest me what to do.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Please do lymph node biopsy

Been diagnosed with Typhoid fever and undergoing treatment for 12 days now with Milixim-O. Dull pain persisting in left armpit (lymph node), temperature fluctuates between 37.4 degrees and 38.2, slight headache which comes and goes, general malaise and body aches. Good appetite and no stomach problems. Should i continue with current treatment program or find another doctor?

Dr. Sfurti Mann

Internal Medicine

Get the lymph node FNAC to find the cause

My dad (aged 71, physically active, no medical complication history), recently undergone open radical prostatectomy with Bilateral Retroperitoneal Lymph Node Dissection. Doctor mentioned a positive node identified. Injected Luprodex 22.5 mg before discharge from the hospital and prescribed Bicalutamide for 9 months. Want to understand is their anything worrisome here? What's the chance of recurrence and if the given medications enough?

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

He requires treatment with radiationU can discuss in cancer hospital

What is Node 50 Injection used for?

Node 50 Injection belongs to the group of medicines called anabolic steroids. It is used to treat osteoporosis in postmenopausal women, certain types of anemia, and breast cancer (in women). It can also be used to treat patients on long-term steroid therapy.

Who should not take Node 50 Injection?

Individuals should not use Node 50 Injection if they have prostate cancer, male breast cancer, breast cancer in women with high calcium levels, certain kidney diseases, or if they are pregnant.

What are the major warnings for Node 50 Injection?

Node 50 Injection can cause serious liver problems such as blood-filled cysts or liver tumors, changes in cholesterol that increase heart disease risk, swelling due to fluid retention, and high calcium levels in women with certain cancers.

What precautions should I take while using Node 50 Injection?

While using Node 50 Injection, your doctor will monitor your liver, heart, and kidney health, blood calcium, cholesterol levels, and bone growth in children. Women should watch for signs of masculinization, such as a deep voice or facial hair.

Can Node 50 Injection be used to improve sports performance?

No, Node 50 Injection is not approved or safe for enhancing athletic performance. Misuse can cause serious health risks and is banned in competitive sports.

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Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Calcium

Related ayurvedic ingredients

Olive oil

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Central Drugs Standard Control Organisation (CDSCO). [Accessed 3 Apr. 2019] (online) Available from:
Nandrolone decanoate injection [Product Information]. Corona, CA: Watson Laboratories, Inc.; 2007. [Accessed 25 Jul. 2024] (online) Available from:
Gascón A, Belvis JJ, Berisa F, et al. Nandrolone decanoate is a good alternative for the treatment of anemia in elderly male patients on hemodialysis. Geriatr Nephrol Urol. 1999;9(2):67-72. [Accessed 25 Jul. 2024] (online) Available from:
Nandrolone decanoate injection [Product Information]. Auckland, New Zealand: Merck Sharp & Dohme (New Zealand) Ltd; 2013. [Accessed 07 Jul. 2025] (online) Available from:
Leeford. [Accessed 07 Jul. 2025] (online) Available from:
Leeford. [Accessed 07 Jul. 2025] (online) Available from: