Nizral Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.
Nizral Tablet should be taken in the dose and duration as prescribed by your doctor. They should be swallowed whole and taken with food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it.
The most common side effects of this medicine include stomach pain, headache, feeling sick (nausea), and abnormal liver function. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint, and nausea. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, a weak immune system (including HIV/AIDS), or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. The drugs may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nizral
Nausea
Vomiting
Abdominal pain
Adrenal insufficiency
Application site burning
Increased liver enzymes
Application site redness
Itching
Diarrhea
Abnormal liver function tests
How to use Nizral Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nizral Tablet is to be taken with food.
How Nizral Tablet works
Nizral Tablet is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your fungal infection.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nizral Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Nizral Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Nizral Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Nizral Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Nizral Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Nizral Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Nizral Tablet should be used with caution in patients with liver disease. Dose adjustment of Nizral Tablet may be needed. Please consult your doctor.
What if you forget to take Nizral Tablet?
If you miss a dose of Nizral Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Your doctor has prescribed Nizral Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Take it with food, preferably at the same time every day.
Do not take indigestion remedies (antacids) within two hours of taking Nizral Tablet.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Inform your doctor if you experience an allergic reaction like skin rash, swelling of face and shortness of breath.
Fact Box
Chemical Class
Azole derivatives {Imidazoles}
Habit Forming
No
Therapeutic Class
OPHTHAL OTOLOGICALS
Action Class
Fungal Ergosterol Synthesis Inhibitor
Interaction with drugs
Taking Nizral with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Simvastatin with Ketoconazole. If Ketoconazole is essential, your doctor may temporarily stop Simvastatin. Ketoconazole may raise blood levels of Simvastatin.
Concur... More
Do not consume Lovastatin with Ketoconazole. If Ketoconazole is essential, your doctor may temporarily stop Lovastatin. Ketoconazole may raise blood levels of Lovastatin.
Concurren... More
Do not consume Ranolazine with Ketoconazole. If concurrent use is essential, watch out for symptoms such as tiredness, nausea, palpitations or numbness. Your doctor may monitor you... More
Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine.
Concurrent use may cause gangrene of fingers and toes.
Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine.
Concurrent use may cause gangrene of fingers and toes.
Hello sir, my name is PATIENT from ambala. Sir, in my chest a black mark is going to very big. and I have no idea what is it plz check the image and tell me what I do
Dr. Atula Gupta
Dermatology
This is a fungal infection. . Tab AF 400 mg one tablet . Repeat this tablet after 1 week . Apply nizral cream over area once at night for a full month and sertacide b cream once in the day for 1 week only
Tab. AF 400mg once a week for 2 weeks ( 2 Tab. to be taken 1 week apart) Nizral Cream / Kz Cream for application twice daily for 1 month. Wash with K2 Zole Soap for 1 month. Complete full Course for permanent solution. Keep body Dry.
I travelled by train in humid & moist day of last sunday after that day, these spots appeared on my groin area Last two day I applied lulibet cream over it
Dr. Souvik Sardar
Dermatology
apply terbicip cream-twice daily for 2months continuously and nizral cream - twice daily for 2monthsand apply lulibet once daily at bedtime
I have been suffering from Pityriasis versicolor I want to know the treatment for is there any cream for this disease
Dr. Atula Gupta
Dermatology
Tab. AF 400mg 1 stat . Repeat after 1 week.K-Z Cream / Nizral Cream ( Ketoconazole 2% cream ) twice daily for 1 month.Complete full Course for permanent solution. Keep body Dry.
I am getting dandruff but the color is yellow. I have tried different anti dandruff shampoo but it's not going. Can you please assist?
Dr. Atula Gupta
Dermatology
For Dandruff- Keraglo AD Shampoo for application three times in a week.Sebowash Shampoo once in a week.Stop oil application over scalp.Tab. Nizral 200mg twice daily for 5 days.
Nizral Tablet is an antifungal medicine used to treat serious fungal infections that affect the lungs, skin, or other parts of the body when other treatments are not available or have failed.
Is Nizral Tablet safe for all types of fungal infections?
No. Nizral Tablet is not meant for common skin or nail fungal infections due to serious side effects. It should only be used for life-threatening or serious systemic fungal infections.
Can Nizral Tablet cause serious side effects?
Yes. Nizral Tablet may cause severe liver damage, which can be life-threatening. Symptoms include yellowing of the skin or eyes, dark urine, or persistent tiredness. Your doctor may advise regular liver monitoring while you are on Nizral Tablet treatment.
Who should not take Nizral Tablet?
Individuals should not take Nizral Tablet if they have liver disease, are taking certain medications that interact dangerously with it (like some heart medications), or are allergic to ketoconazole or any other ingredient present in Nizral Tablet.
Can Nizral Tablet cause hormone changes?
Yes. Long-term use of Nizral Tablet may affect hormone levels, especially testosterone and cortisol, possibly leading to breast enlargement in men or menstrual changes in women.
What precautions should I take while using Nizral Tablet?
While using Nizral Tablet, you should avoid alcohol, get regular liver function tests, inform your doctor of any new symptoms, and do not self-medicate or combine with other antifungals.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Schimmer BP, Funder JW. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1233.
Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1576.
Chrousos GP. Adrenocorticosteroids & Adrenocortical Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 693.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 758-59.
Ketoconazole. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2014. [Accessed 29 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
Ketoconazole [Prescribing Information]. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2014. [Accessed 13 Mar. 2024] (online) Available from:
Marketer details
Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060