Nitobris 100mg Tablet SR is an antibiotic that fights bacteria. It is used to treat and prevent bacterial infections of the urinary tract. It works by killing the bacteria that cause such disease. But, it will not treat a viral infection.

Nitobris 100mg Tablet SR should be taken in the dose and duration as advised by the doctor. You may take it with food to avoid nausea, which is a common side effect. It is better to have this medicine at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.
Some people may develop side effects like nausea, vomiting, and diarrhea. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. This medicine may turn your urine into dark yellow or brown color. But, this is normal and nothing to worry about.
Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any antibiotic.

Uses of Nitobris Tablet SR

Treatment of Bacterial infections of urinary tract

Benefits of Nitobris Tablet SR

In Treatment of Bacterial infections of urinary tract

Nitobris 100mg Tablet SR works by stopping the growth of the bacteria in the urine that cause urinary tract infections. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Nitobris Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nitobris

Nausea
Vomiting
Diarrhea

How to use Nitobris Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nitobris 100mg Tablet SR is to be taken with food.

How Nitobris Tablet SR works

Nitobris 100mg Tablet SR is an antibiotic. It works by killing the bacteria in the urine that causes infection.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Nitobris 100mg Tablet SR may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Nitobris 100mg Tablet SR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CAUTION

Nitobris 100mg Tablet SR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

Nitobris 100mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nitobris 100mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nitobris 100mg Tablet SR may be needed. Please consult your doctor.

Liver

CAUTION

Nitobris 100mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nitobris 100mg Tablet SR may be needed. Please consult your doctor.

What if you forget to take Nitobris Tablet SR?

If you miss a dose of Nitobris 100mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nitobris 100mg Tablet SR

₹7.95/Tablet SR

Nitrobest Tablet SR

Lupin Ltd

₹8.87/tablet sr

12% costlier

Nitrofur SR Tablet

Wanbury Ltd

₹9.07/tablet sr

14% costlier

Nifutin Tablet SR

Ipca Laboratories Ltd

₹9.08/tablet sr

14% costlier

Urifur 100mg Tablet SR

Stadmed Pvt Ltd

₹8.83/tablet sr

11% costlier

Nifnext SR Tablet

Cadila Pharmaceuticals Ltd

₹8.47/tablet sr

7% costlier

View all substitutes

Quick tips

Nitobris 100mg Tablet SR treats and prevents uncomplicated urinary tract infections.
Finish the prescribed course of the medicine, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Take it with food to avoid nausea, which is a common side effect.
It can turn your urine a dark yellow or brown colour. This is normal and nothing to worry about.
Do not take it for longer or more often than prescribed by your doctor.

Fact Box

Chemical Class

Nitrofurans derivatives

Habit Forming

Therapeutic Class

UROLOGY

Action Class

Urinary Antiseptic-Nitrofurantoin

Interaction with drugs

Taking Nitobris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Purified Vi Polysaccharide Typhoid Vaccine (Oral Route) Severe

Nitrofurantoin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Do not consume Purified Vi Polysaccharide Typhoid Vaccine with Nitrofurantoin. If Purified Vi... More

Cholera Vaccine (Inactivated) (Oral Route) Severe

Nitrofurantoin may reduce the efficacy of Cholera Vaccine (Inactivated). Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Nitrofu... More

Clozapine (Oral Route) Moderate

Concurrent use may increase the risk of low blood cell counts. Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Levofloxacin (Oral Route) Mild

Nitrofurantoin may increase the metabolism of Levofloxacin. Talk to your doctor if you notice any unusual symptoms.

Ciprofloxacin (Oral Route) Mild

Nitrofurantoin may reduce blood levels and efficacy of the active form of Ciprofloxacin. Talk to your doctor if you notice any unusual symptoms.

View all drug interactions

Patient concerns

Prostrate check up Urinary tract infections

Dr.

Gastroenterology

Needs antibiotics Meet a urologist

Having urine infection since about a month. Took several antibiotics after consultation with doctor but they all show effect only for starting 2 days and then that antibiotic doesn't work. I have taken sporidex 500, zefu cv 500, norflox 400, levofloxin, cefodoxime (each taken for atleast 4-5 days). All work for starting two days then no effect and infection starts to increase. Urine culture report is attached. Kindly suggest medication since problem is increasing day by day.

Dr. Ila Jain Khandelwal

Pathology

You should consult a urologist and get a few tests done since we need to know the cause of your recurrent urinary tract infections.

FAQs

How long does Nitobris 100mg Tablet SR take to work on a UTI?

Nitobris 100mg Tablet SR starts acting quickly, but you will not start feeling better immediately after taking it. It may take a few days (2-3 days) before you see any improvement in your symptoms. If you do not start feeling better within 3 days of starting Nitobris 100mg Tablet SR or your condition worsens, contact your doctor. It is important to complete the full course of Nitobris 100mg Tablet SR as advised by your doctor, even if you start feeling better.

What happens if you take Nitobris 100mg Tablet SR without food?

You should take Nitobris 100mg Tablet SR with your meal or straightaway after the meal. Taking with food helps in absorption of medicine so that it works better. If you take it without food, you are likely to get an upset stomach. The symptoms include nausea, vomiting, diarrhoea, and loss of appetite may also occur. Therefore, to avoid unpleasant side effects, take it exactly as prescribed by your doctor.

Does Nitobris 100mg Tablet SR make your urine orange?

Nitobris 100mg Tablet SR may turn your urine brown or dark yellow in colour. However, you need not worry as this is usually temporary and completely harmless effect. It will disappear once you stop taking Nitobris 100mg Tablet SR. Consult your doctor if you are not sure or still have any concern, but do not stop taking Nitobris 100mg Tablet SR.

Can Nitobris 100mg Tablet SR give you a yeast infection?

Yes, some people may get a fungal or yeast infection known as ‘thrush’ after taking Nitobris 100mg Tablet SR. This is because antibiotics kill the ‘good bacteria’ which help in preventing thrush. You should inform your doctor if you get vaginal itching or discharge after taking Nitobris 100mg Tablet SR or soon after stopping it.

Is Nitobris 100mg Tablet SR a strong antibiotic?

Yes, Nitobris 100mg Tablet SR is a strong antibiotic (or broad spectrum antibiotic), which means that it is effective against a wide variety of urinary bacteria. It is important that Nitobris 100mg Tablet SR should be given to treat or prevent infections that are proven to be caused by susceptible bacteria. This is usually evaluated by a culture test which demonstrates a range of bacteria which cannot grow in the prence of an antibiotic. Nitobris 100mg Tablet SR has seen to be effective against UTI caused by Escherichia coli, Enteroccus faecalis, Klebsiella species, Enterobacter species, Staphylococcus species: (eg S. aureus, S. saprophyticus, S. epidermidis). Some strains of Enterobacter and Klebsiella are resistant to Nitobris 100mg Tablet SR.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1474-75.
Chambers HF, Deck DH. Miscellaneous Antimicrobial Agents; Disingectants, Antiseptics, & Sterilants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 878.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 984-86.
Nitrofurantoin. North Norwich, New York: Norwich Pharmaceuticals, Inc.; 2008. [Accessed 28 Mar. 2019] (online) Available form:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Nitrofurantoin monohydrate/macrocrystals [Prescribing Information]. North Norwich, NY: Norwich Pharmaceuticals, Inc.; 2008. [Accessed 06 Apr. 2023] (online) Available from:

Marketer details

Name: Lanchestor Biotech

Address: Plot no. 455 Phase 1,, Ind. area, Panchkula, Haryana., Panchkula Haryana 134113

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.