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Mycocox E 450 mg/300 mg/800 mg Tablet


Overview

Introduction

Mycocox E 450 mg/300 mg/800 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Mycocox E 450 mg/300 mg/800 mg Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Mycocox E Tablet

Side effects of Mycocox E Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mycocox E

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Increased liver enzymes
  • Jaundice
  • Visual impairment
  • Increased uric acid level in blood
  • Gout
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Sweating
    Try wearing loose, light-weighted, and breathable clothing. Use a strong antiperspirant and keep yourself cool with a fan. Changing your shoes and socks often might also help. Try cutting down on coffee, tea, and alcohol as they can increase your body temperature and promote sweating. Avoid spicy foods, this will help you deal with excessive sweating. If this does not help, talk to your doctor about other possible medications.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.
  • Coping with Gout
    You can help ease the pain by resting and raising the affected limb. Keep the joint cool by applying an ice pack. To prevent flare-ups, drink plenty of fluids but limit or avoid alcohol. Coffee and vitamin C are also believed to lower levels of uric acid which causes gout. Cut down on sugary drinks and avoid foods such as red meat, offal and seafood as they can make your gout worse. If your gout gets worse when taking this medicine, talk to your doctor. There may be an alternative.

How to use Mycocox E Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mycocox E 450 mg/300 mg/800 mg Tablet is to be taken empty stomach.
Avoid Mycocox E 450 mg/300 mg/800 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Mycocox E Tablet works

Mycocox E 450 mg/300 mg/800 mg Tablet is a combination of three medicines: Rifampicin, isoniazid and ethambutol, which treats tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.

Safety Advice

Alcohol
UNSAFE
Consuming alcohol while taking Mycocox E 450 mg/300 mg/800 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Mycocox E 450 mg/300 mg/800 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Mycocox E 450 mg/300 mg/800 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Mycocox E 450 mg/300 mg/800 mg Tablet may cause side effects which could affect your ability to drive.
Mycocox E 450 mg/300 mg/800 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Mycocox E 450 mg/300 mg/800 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mycocox E 450 mg/300 mg/800 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Mycocox E 450 mg/300 mg/800 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mycocox E 450 mg/300 mg/800 mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mycocox E 450 mg/300 mg/800 mg Tablet
₹8.91/Tablet
Trac 3 450 mg/300 mg/800 mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.82/Tablet
save 57%
Rhe-Kit Tablet
Macleods Pharmaceuticals Pvt Ltd
₹7.98/Tablet
save 10%
Monto 3 Tablet
Shreya Life Sciences Pvt Ltd
₹10.01/Tablet
12% costlier
₹13.94/Tablet
56% costlier
Rhe-FD Tablet
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₹15.28/Tablet
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Quick Tips

  • It is best to take the medicine on an empty stomach one hour before or two hours after meals.
  • Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the infection harder to treat.
  • It can make birth control pills less effective so ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).
  • It can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. 

Patient Concerns

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Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetology
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
Dear Doctor, I had a by surgery in 2013. In April I got the checkup done. All test are normal except I have slightly high BP. I have been taking these medicine on the advice of my cardiologist. CILACAR 10 MG TABLET - M/E CTD 6.25 MG TABLET - M HOPACE 5 MG Tablets - M/E ROSUVAS 10 MG TABLET - E STARPRESS-XL 50 MG TABLET - M Could you pl. suggest some cheaper alternative medicines? Thank you
Dr. Nabajit Talukdar
Cardiology
U can go for generics
arrow
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User Feedback


FAQs

Q. Which is the best time to take Mycocox E?

Take Mycocox E exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Q. Can the use of Mycocox E make birth control pills ineffective?

Yes, Mycocox E can make birth control pills less effective. Ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Q. Is tuberculosis a curable disease?

Yes, tuberculosis (TB) is a curable disease and can be cured with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side effects.

Q. What are the instructions for the storage and disposal of Mycocox E?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Mycocox E cause discoloration of the urine?

Yes, Mycocox E contains rifampicin which can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).

Q. Can I discontinue Mycocox E if I feel well?

No, do not discontinue Mycocox E. Take the proper course of the drug that has been prescribed to you even if you begin to feel better. If you stop taking Mycocox E, your infection may become worse and difficult to treat. It may even result in drug-resistant TB i.e. drugs you were taking may no longer work for Tuberculosis.

Q. Can Mycocox E cause visual impairment?

Mycocox E contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 10 Apr. 2019] (online) Available from:External Link

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