Metolactone 5 mg/50 mg Tablet

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Centaur Pharmaceuticals Pvt Ltd

Composition for Metolactone 5 mg/50 mg Tablet

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Primarily used for

Hypertension, Heart failure, Fluid retention (edema)
Potentiallyunsafewith
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Alcohol
52.61
₹5.26/Tablet
10 tablets in 1 strip
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Medicine Overview of Metolactone 5 mg/50 mg Tablet

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Uses of Metolazone

Metolazone is used in hypertension, heart failure, Fluid retention (edema) and kidney stone.
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Side effects of Metolazone

Common

Headache, Nausea, Increased blood uric acid, Decreased potassium level in blood, Glucose intolerance, Altered blood lipids.

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How to use Metolazone

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Metolactone 5 mg/50 mg Tablet with food.

How Metolactone 5 mg/50 mg Tablet works

Metolazone is a thiazide diuretic. It lowers blood pressure and fluid retention in edema by removing the extra water and electrolytes from the body.
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Uses of Spironolactone

Spironolactone is used in the treatment of hypertension, heart failure, cirrhosis and low potassium.
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Side effects of Spironolactone

Common

Nausea, Vomiting, Leg cramps, Dizziness, Drowsiness, Confusion, Breast enlargement in male, Increased creatinine level in blood.

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How to use Spironolactone

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Metolactone 5 mg/50 mg Tablet with food.

How Metolactone 5 mg/50 mg Tablet works

Spironolactone lowers the swelling by removing the levels of excess water and electrolytes in the body. Spironolactone does this without loss of potassium from the body.

In Depth Information on Metolactone 5 mg/50 mg Tablet

Expert advice for Metolazone

  • Do not take metolazone tablets, if you are allergic (hypersensitive) to sulfa drugs, thiazides, any other medications, metolazone or any of the other ingredients of metolazone tablet.
  • Do not take metolazone, if you are unable to urinate; if you have precoma or are in a coma caused by severe liver disease; if you have kidney or liver problem.
  • Avoid using metolazone, if you are pregnant or breastfeeding.
  • Consult your doctor, if you have or ever had diabetes, gout, low blood sodium or potassium levels, systemic lupus erythematosus.
  • Avoid prolonged exposure to sunlight.
  • Do not drive or operate machinery after taking metolazone.

Expert advice for Spironolactone

The medicine  can make you feel dizzy or sleepy. Avoid driving or operating machinery until you know how the medicine affects you. Do not use supplements or salt substitutes that are high in potasium. Consult your doctor if you develop any muscle weakness, skin changes, red or black tarry stool. Avoid taking alcohol with this medication as it may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. Do not start or continue spironolactone and consult your doctor:
  • If you have kidney disease, Addison’s disease (an adrenal gland disorder), liver disease, heart disease.
  • If you have high levels of potassium in your blood (hyperkalemia).
  • if you are also taking eplerenone or other potassium sparing diuretics.
  • If you have an electrolyte imbalance (such as low levels of magnesium in your blood).
  • if you take an NSAID (nonsteroidal anti-inflammatory drug), cholestyramine, heparin, lithium, heart or blood pressure medication, potassium supplements, steroid medicine, or another diuretic.
Warnings
Special precautions for Metolactone 5 mg/50 mg Tablet
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Alcohol
CAUTION
Taking Metolazone with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
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Pregnancy
WEIGH RISKS VS BENEFITS
Metolactone 5 mg/50 mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
Metolactone 5 mg/50 mg Tablet is probably safe to use during
lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
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Driving
Do not drive unless you are feeling well.

As Metolactone 5 mg/50 mg Tablet may cause drowsiness, dizziness, blurred vision, or lightheadedness and this may affect your ability to drive.
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Kidney
CAUTION
Metolactone 5 mg/50 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metolactone 5 mg/50 mg Tablet may be needed. Please consult your doctor.

Use of Metolactone 5 mg/50 mg Tablet is not recommended in patients with severe kidney disease.
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Liver
There is limited information available on the use of Metolac
tone 5 mg/50 mg Tablet in patients with liver disease. Please consult your doctor.
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Patient Concerns

Frequently asked questions for Metolactone 5 mg/50 mg Tablet

Frequently asked questions for Metolazone

Q. Is metolazone potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic?
Metolazone belongs to the group of medicines called quinazoline and thiazide-like diuretic and it is not potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic
Q. Is metolazone discontinued?
No, metolazone is not discontinued
Q. Is metolazone stronger than Lasix?
Metolazone and furosemide (Lasix) belongs to same category of drugs (diuretics), but their effect may vary upon individual response
Q. Can you take metolazone with Lasix?
Metolazone and furosemide (Lasix) may sometimes be prescribed, but these combinations can lead to dehydration and electrolyte abnormalities. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does metolazone contain sulfa?
Yes, it contains sulfa. Chemically it is called as 7-chloro-2-methyl-4-oxo-3-o-tolyl-1, 2, 3, 4-tetrahydroquinazoline-6-sulfonamide
Q. Does metolazone get you high/ deplete potassium?
Metolazone causing the above side effects is uncommon or rare. However consult your doctor if you experience any of these side effects
Q. Does metolazone appear in breast milk?
Yes, metolazone gets excreted in breast milk. Patient should follow the advice of the doctor regarding its use
Q. How long does metolazone take to work?
It depends upon disease condition and lot of other factors. Patient should follow the advice of the doctor regarding its use.
Q. Can I use Metolazone with Torasemide?
Both Metolazone and Torasemide are diuretics and both can lower the blood potassium levels (hypokalemia). When given together, hypokalemia can be severe, causing muscle pains or cramps, loss of appetite, weakness, dizziness, or confusion. Inform your doctor if you have these symptoms and you are taking both the drugs. Take foods rich in potassium like orange or other citrus fruit juices or take a potassium supplement.
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Frequently asked questions for Spironolactone

Q. What is spironolactone?
Spironolactone is a diuretic and belongs to the class of potassium sparing diuretics (water tablets), which help to lose excess fluid from your body. They may be used for congestive heart failure, nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (oedema) and swelling of the abdomen (ascites), a cancerous disease with swelling of the abdomen (malignant ascites) and diagnosis and treatment of primary aldosteronism (a condition where excess hormone is produced).
Q. Is spironolactone an over the counter drug?
Spironolactone is not an over the counter medicine. It is a prescription drug and is available only with a valid prescription by a doctor.
Q. Can spironolactone cause constipation?
Spironolactone has not been reported to cause constipation. Talk to your doctor if you have constipation while taking spironolactone as it could be due to some other underlying condition.
Q. Can I take spironolactone with indomethacin?
Indomethacin may increase the diuretic effect of spironolactone and both can increase the potassium levels in the blood. Patients should follow doctors advice if these two medicines are to be used together.
Q. Can I use spironolactone for weight control?
Spironolactone does not cause weight loss and is not used for weight control. Please consult a doctor for the right therapy for weight control.
Q. Can I take spironolactone with paracetamol (acetaminophen)?
Spironolactone can be taken with paracetamol (acetaminophen). No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone forever?
Spironolactone should be taken for a duration as advised by your doctor.
Q. How long can I take spironolactone for acne?
Do not take spironolactone for acne unless advised by your doctor as it is not approved for use in this condition. If you are given spironolactone for acne, please take it for a duration as advised by your doctor.
Q. Can males take spironolactone for acne?
Spironolactone in used for treating acne in males. While it does decrease sebum production and can be helpful, it is not used in men because it blocks the action of androgens (male hormone) at the receptor sites in tissue and can cause feminizing physical side effects. If you are a male and suffering from acne, please consult your doctor before taking any medicines for your condition.
Q. Is spironolactone an angiotensin converting enzyme (ACE) inhibitor?
Spironolactone is not an ACE inhibitor. It is a potassium-sparing diuretic (water tablets), which helps you lose excess fluid from your body.
Q. Is spironolactone a thiazide diuretic?
Spironolactone is not a thiazide diuretic. It belongs to a different class of diuretics known as the potassium-sparing diuretics (water tablets), which helps you lose excess fluid from your body.
Q. Can I take spironolactone with birth control?
Spironolactone can be taken with birth control pills (oral contraceptives) as no drug-drug interactions or side effects have been reported when used together. However, interactions can occur. Talk to your doctor before taking spironolactone with any birth control pills (oral contraceptives).
Q. Can I take spironolactone with phentermine?
Spironolactone can be taken with phentermine. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone with amoxicillin?
Spironolactone can be taken with amoxicillin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone without birth control?
Spironolactone alone is used to treat conditions like congestive heart failure, nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (edema) and swelling of the abdomen (ascites). Spironolactone with birth control pills (oral contraceptives) is used in women for the treatment of their acne. However, it is not yet approved for the treatment of acne. Talk to your doctor before taking any medicine for acne.
Q. Can I take spironolactone with metformin?
Spironolactone can be taken with metformin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone with isotretinoin?
Spironolactone can be taken with isotretinoin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone with guaifenesin?
Spironolactone can be taken with guaifenesin. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Can I take spironolactone with vitamins?
Spironolactone can be taken with vitamins. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. Does spironolactone cause weight gain?
Spironolactone does not cause weight gain. Please consult your doctor if you experience weight gain while taking spironolactone.
Q. Does spironolactone stop your period?
Spironolactone does not stop period, however, it can cause irregular periods. Please consult your doctor if you experience irregular periods while taking spironolactone.
Q. Does spironolactone help hirsutism (excessive hair growth)?
Spironolactone can be used for the treatment of hirsuitism. Do not take spironolactone for hirsuitism unless advised by your doctor.
Q. Does spironolactone cause weight loss?
Spironolactone does not cause weight loss. Please consult your doctor if you experience weight loss while taking spironolactone as it could be due to some other underlying conditions.
Q. Does spironolactone cause hair loss?
Spironolactone can cause hair loss. Please consult your doctor if you experience hair loss while taking spironolactone as the dose of the drug may needs to be changed.
Q. Does spironolactone cause depression?
Spironolactone does not cause depression. Please consult your doctor if you experience depression while taking spironolactone.
Q. Does spironolactone help with acne?
Spironolactone is not approved for treating acne. However, it has been seen to be effective in treating acne in females. It is prescribed and paired with a birth control pill. A significant number of patients have reported that they have seen positive results in the pairing of these two medications, although these results may not be seen for up to three months. Talk to your doctor if you are suffering from acne as the therapy should be started only when advised by a doctor.
Q. Does spironolactone cause hyponatremia?
Spironolactone can cause hyponatremia (very low level of sodium in the blood). Hyponatremia signs and symptoms may include nausea and vomiting, headache, confusion, loss of energy and tiredness, restlessness and irritability, muscle weakness, spasms or cramps, seizures, and coma. Please consult your doctor if you have the signs and symptoms of hyponatremia as it requires proper diagnosis and management.
Q. Does spironolactone increase estrogen?
Spironolactone is not known to increase estrogen levels. Spironolactone is a steroid that blocks the effects of the hormones aldosterone and testosterone and has some effects similar to those of the hormone progesterone.
Q. Does spironolactone work?
Spironolactone works if taken for the right indication for a prescribed duration in prescribed doses as advised by your doctor.
Q. Is spironolactone safe?
Spironolactone is safe if taken for prescribed duration in prescribed doses as advised by your doctor.
Q. Is spironolactone a diuretic?
Spironolactone is a diuretic and belongs to the class of potassium sparing diuretics (water tablets), which help to lose excess fluid from your body. They may be used for congestive heart failure, nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (oedema) and swelling of the abdomen (ascites), a cancerous disease with swelling of the abdomen (malignant ascites) and diagnosis and treatment of primary aldosteronism (a condition where excess hormone is produced).
Q. Is spironolactone a steroid?
Spironolactone is a synthetic steroid which works by blocking the effects of the hormones aldosterone. It also blocks the action of testosterone.
Q. Does spironolactone cause insomnia (inability to sleep)?
Spironolactone has not been reported to cause insomnia (inability to sleep). However, it can make you feel drowsy (sleepy). Talk to your doctor in case you have sleep problems while taking this drug.
Q. Is spironolactone a beta blocker?
Spironolactone is not a beta blocker. It is a potassium-sparing diuretic (water tablets), which helps you lose excess fluid from your body.
Q. Is spironolactone a hormone?
Spironolactone is not a hormone. It is a potassium-sparing diuretic (water tablets), which helps you lose excess fluid from your body.
Q. Is spironolactone a blood pressure medication?
Spironolactone not indicated for the treatment of high blood pressure. However, it is a diuretic, which helps you lose excess fluid from your body and can lower your blood pressure especially if you are also taking other blood pressure lowering drugs. Talk to your doctor before taking spironolactone if you are a hypertensive and also taking blood pressure lowering drugs.
Q. Is spironolactone a controlled substance?
Spironolactone is not a controlled substance. It is a prescription medicine and is available on providing a valid prescription.
Q. Is spironolactone harmful to kidneys?
Spironolactone can lead to acute kidney failure particularly in those who already have impaired kidney function. Please tell your doctor if you have kidney problems as you may have to be given a different dose and a close monitoring of your kidney function test may be required.
Q. Is spironolactone a blood thinner?
Spironolactone is not a blood thinner. It is a potassium-sparing diuretic (also known as water tablets).
Q. Does spironolactone cause cancer?
Breast cancer has been reported as a very rare side effect of spironolactone. Talk to your doctor if you have any questions or concern regarding this side effect.
Q. Can I take spironolactone with furosemide?
Both spironolactone and furosemide are diuretics. However, they belong to the different class of diuretics. When used together, they can increase the diuretic effect of each other. Also, spironolactone causes an increase in potassium levels while furosemide decreases the potassium levels. Effect of this interaction is not very clear. So, it is advisable to talk to your doctor before taking the two drugs together.
Q. Can I use Spironolactone with Torasemide?
Spironolactone can be taken along with Torasemide and their combination is quite beneficial in maintaining the blood potassium levels. Torsemide is a loop diuretic and causes loss of potassium from your body while Spironolactone is a potassium-sparing diuretic which prevents the loss of potassium.
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