Methotrex 5 Tablet

Methotrexate (5 mg)

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Methotrex 5 Tablet is a medicine used to treat a severe form of skin disease called psoriasis when other treatments are not effective. The medicine help kills the cells in the skin which are growing too quickly. It may be also used to treat other conditions, as determined by the doctor.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Jul 2026 | 01:05 AM (IST)

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General Information

Contains

Methotrexate (5 mg)

Marketer

Healing Pharma India Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Methotrex 5 Tablet is only meant for external use and should be used as advised by your doctor. Your doctor will decide what dose is necessary and how often you need to use it. Do not stop using the medicine without first checking with your doctor. You should use it exactly as your doctor has advised.

The medicine is generally safe and does not usually cause any side effects. However, if you experience any symptoms on using the medicine, let your doctor know. There may be ways of preventing or reducing these effects.

Before using it, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Let your doctor also if you are taking or using any other medications. This medicine is not recommended during pregnancy or while breastfeeding. It can cause harm to your baby.

Uses of Methotrex Tablet

Treatment of Psoriasis

Benefits of Methotrex Tablet

Treatment of Psoriasis
Methotrex 5 Tablet belongs to a group of medicines called antimetabolites. It is used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Methotrex 5 Tablet works by killing these fast-growing cells. It is a potent and very toxic medicine; discuss the risks and benefits with your doctor.

Side effects of Methotrex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Methotrex

No common side effects seen

How to use Methotrex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Methotrex 5 Tablet may be taken with or without food.

How Methotrex Tablet works

Methotrex 5 Tablet is an immunosuppressant. In psoriasis, it works by slowing down the rapid growth of skin cells.

Quick tips

Apply Methotrex 5 Tablet only to the affected area as directed and do not use on broken, irritated, or infected skin.
Wash your hands before and after applying to prevent the medicine from spreading to other areas.
Avoid sun exposure on the treated area and use sunscreen or cover it when outdoors.
Do not cover the treated area with bandages or tight clothing unless your doctor says it is okay.
Let your doctor know if you notice skin peeling, severe redness, or burning after Methotrex 5 Tablet use.

Safety advice

Alcohol

SAFE

Consuming alcohol with Methotrex 5 Tablet does not usually cause any harmful side effects.

Pregnancy

UNSAFE

Methotrex 5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Methotrex 5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Methotrex 5 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Methotrex 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test is advised while you are taking this medicine.

Liver

UNSAFE

Methotrex 5 Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Methotrex 5 Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

Is Methotrex 5 Tablet effective?

Methotrex 5 Tablet is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Methotrex 5 Tablet too early, the symptoms may return or worsen.

How to use Methotrex 5 Tablet?

Before using Methotrex 5 Tablet, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Methotrex 5 Tablet gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

What precautions do I need to take while using Methotrex 5 Tablet?

Be careful not to get Methotrex 5 Tablet into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Methotrex 5 Tablet if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Methotrex 5 Tablet with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive to avoid any harm to the baby. Pregnant and breastfeeding mothers should use Methotrex 5 Tablet only if prescribed by the doctor.

What should I do if I forget to use Methotrex 5 Tablet?

If you forget to use Methotrex 5 Tablet, do not worry and continue using Methotrex 5 Tablet as soon as you remember. Do not double the dose to make up for the missed dose. However, if you are not sure and have any other doubts, please consult your doctor.

Fact Box

Chemical Class

Glutamic acid derivative

Habit Forming

Therapeutic Class

DERMA

Action Class

Antimetabolite- Methotrexate

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
Central Drugs Standard Control Organisation. Methotrexate. [Accessed 11 Jul. 2023]. (online) Available from:
Eskicirak B, Zemheri E, Cerkezoglu A. The treatment of psoriasis vulgaris: 1% topical methotrexate gel. Int J Dermatol. 2006 Aug;45(8):965-9. [Accessed 11 Jul. 2023]. (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Healing Pharma India Pvt Ltd
Address: Gala No. 5 to 13, Gr. Flr., Bldg. No. E-15/A,Harihar Complex, Bhiwandi, Mumbai-421302

Vendor Details

Country of origin: India

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Methotrex 5 Tablet

Methotrex 5 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Methotrex Tablet

Benefits of Methotrex Tablet

Side effects of Methotrex Tablet

How to use Methotrex Tablet

How Methotrex Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Methotrex 5 Tablet effective?

How to use Methotrex 5 Tablet?

What precautions do I need to take while using Methotrex 5 Tablet?

What should I do if I forget to use Methotrex 5 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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