Content Details
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
16 Jul 2019 | 05:18 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Metaglez Tablet


Overview

Introduction

Metaglez Tablet is a medicine used in the treatment of type 2 diabetes.

Metaglez Tablet is a combination of two medicines that effectively controls blood sugar levels when a single medication is not effective. It should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid side effects like nausea and stomach upset.

Uses of Metaglez Tablet

Metaglez Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Stomach pain
  • Diarrhea
  • Headache
  • Upper respiratory tract infection

How to use Metaglez Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metaglez Tablet is to be taken with food.
Metaglez Tablet may cause stomach upset if taken on empty stomach

How Metaglez Tablet works

Metaglez Tablet is a combination of two antidiabetic medicines: Glipizide and Metformin. Glipizide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Metaglez Tablet related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Metaglez Tablet Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
CONSULT YOUR DOCTOR
Metaglez Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
SAFE IF PRESCRIBED
Metaglez Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Metaglez Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metaglez Tablet may be needed. Please consult your doctor.
Use of Metaglez Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Metaglez Tablet should be used with caution in patients with liver disease. Dose adjustment of Metaglez Tablet may be needed. Please consult your doctor.
Metaglez Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Metaglez Tablet
₹0.48/Tablet
₹0.78/Tablet
63% costlier
Glicept 2.5mg/400mg Tablet
Strides shasun Ltd
₹0.47/Tablet
same price

Expert Advice

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Metaglez Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Metaglez

arrow
Sir/madam Diabetes type--Type-2 Diabetes Im taking 1 tablet in morning after TIFFIN. Tablet--GLYCOMET-GP2 FORTE. This 1 tablet sufficient as my Diabetes checkup results.& My liver Mildly enlarged this is my problem so pls expalin only 1 Tablet wii effect on any parts of my body Pls ExplainFBS-170 PPBS-190
Dr. Sanjay Bhatt
Diabetes Specialist
Need to examine and priscribe medicine for you.Without examine , can't priscribe any medicine in your case.so plz consult doctor near by or can visit our clinic
I have type 2 diabetes. Can I use IME-9 tablets.if yes. Tell me the dosage and when
Dr. Deepak Kumar Soni
Skin Specialist
yes you can usehttps://www.1mg.com/otc/ime-9-tablet-otc3286611-1 Tablet after lunch & dinner,take this medicine along with your treatment
arrow
Do you have any questions related to Metaglez Tablet?

User Feedback


FAQs

Q. What is Metaglez?

Metaglez is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Metaglez?

The use of Metaglez is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.

Q. Can the use of Metaglez cause hypoglycemia?

Yes, the use of Metaglez can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.

Q. Can the use of Metaglez cause lactic acidosis?

Yes, the use of Metaglez can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Metaglez and immediately consult your doctor.

Q. Can the use of Metaglez lead to Vitamin B12 deficiency?

Yes, the use of Metaglez can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Metaglez should not to be taken?

The use of Metaglez should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Metaglez?

No, it is not safe to take Metaglez along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Metaglez?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glipizide+metformin HCl. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 29 Jan. 2019] (online) Available from:External Link
  2. Drugs.com. Glipizide+Metformin. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glipizide and Metformin Hydrochloride. Ahmedabad, India: Cadila Healthcare Ltd; 2016. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
BANNED FOR SALE
As per the Drugs and Cosmetics Act, Ministry of Health and Family Welfare

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
+91
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Enjoy 20% off on allopathy medicines, up to 50% off on health products, up to 80% off on lab tests and free doctor consultations

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mg
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.