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Metadoxil 500mg Tablet

Metadoxine (500mg)
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Metadoxil 500mg Tablet is an antioxidant medicine used to treat alcoholic fatty liver. It works by protecting the liver from harmful chemical substances and also increases the alcohol elimination from the blood and tissues.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 01 Jan 2026 | 09:03 PM (IST)
₹132 MRP ₹144.218% off 
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Metadoxil 500mg Tablet
Metadoxil 500mg Tablet
strip of 10 tablets
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₹144.21
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Same composition
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General Information

The content is shown in English
Metadoxil 500mg Tablet image
Metadoxil 500mg Tablet image

Product introduction

Metadoxil 500mg Tablet should be taken with or without food. The dose will depend on what you are being treated for and your body weight. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

The most common side effects are nausea, upset stomach, and diarrhea. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines, so tell your doctor about all the other medicines you are taking.

Benefits of Metadoxil Tablet

Treatment of Alcoholic fatty liver disease
Metadoxil 500mg Tablet belongs to a class of drugs known as hepatoprotectives. It fastens the clearance of alcohol from the blood and therefore helps in the treatment of fatty liver due to alcoholism. In the long term, it protects the liver from damage against harmful chemicals known as free radicals, thereby improving the overall health of the liver.

Take it in the dose and duration advised by the doctor. Do not stop taking it even if your symptoms disappear. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Metadoxil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metadoxil
  • Nausea
  • Upset stomach
  • Diarrhea

How to use Metadoxil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metadoxil 500mg Tablet may be taken with or without food.

How Metadoxil Tablet works

Metadoxil 500mg Tablet is an antioxidant. It works by protecting the liver from harmful chemical substances (free radicals). It also works by increasing alcohol elimination from the blood and tissues, thus preventing liver damage.

All substitutes for Metadoxil 500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It protects the liver cells from toxins and helps the liver to perform its normal functions.
  • Take it as per the dose and duration suggested by your doctor.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Metadoxil 500mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Metadoxil 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Metadoxil 500mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Metadoxil 500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Metadoxil 500mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Metadoxil 500mg Tablet in patients with liver disease.

Interaction with drugs

Taking Metadoxil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Altretamine (Oral Route)

Do not consume Altretamine with Metadoxine. Metadoxine may reduce the efficacy of Altretamine.
Moderate

Phenytoin (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Metadoxine may raise blood levels of Phenytoin.
Moderate

Phenytoin (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Metadoxine may raise blood levels of Phenytoin.
Moderate

Levodopa (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Metadoxine may slow down the removal of Levodopa from the body.
Mild

Nitrofurantoin (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Metadoxine may reduce blood levels of Nitrofurantoin.

Frequently asked questions

Metadoxil 500mg Tablet belongs to a class of medicines known as hepatoprotective medicines which means that they protect the liver. It is used to treat chronic and acute alcohol intoxication. Metadoxil 500mg Tablet accelerates alcohol clearance from the blood and therefore, also helps in the treatment of fatty liver due to alcoholism.
Metadoxil 500mg Tablet works by increasing the rate of alcohol clearance from blood and tissues, which leads to faster recovery from alcohol intoxication. This in long term protects the liver from damage against harmful chemicals known as free radicals, thereby improving overall health of the liver.
Metadoxil 500mg Tablet may be taken with or without food as prescribed by the doctor. Take it in the dose and duration advised by the doctor. Swallow the tablet whole; do not crush, break or chew. The dose will depend on the condition you are being treated for and your total body weight. It is advised to follow your doctor’s instructions carefully to get maximum benefit of Metadoxil 500mg Tablet.
The most common side effects associated with Metadoxil 500mg Tablet include nausea, upset stomach and diarrhea. However, these effects are not observed in all patients. If you are worried about them or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea.
Metadoxil 500mg Tablet is not advised to be taken by pregnant and breastfeeding women. Consult your doctor before taking Metadoxil 500mg Tablet if you are planning to conceive, pregnant or breastfeeding to prevent harmful effects on the baby.

Fact Box

Chemical Class

Pyridoxine derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Twice A Day
65%
Once A Day
25%
Thrice A Day
10%
Alcoholic fatty liver disease
50%
Non-alcoholic fatty liver
39%
Others
11%
Excellent
73%
Poor
20%
Average
7%
No Side Effect
100%
With or without food
100%
Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Micro Labs Ltd
Address: Mamring Namthang Road, Namchi-737132, Sikkim || 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA || Plot no 37 (CA) 147-151 , 279-281 ,Ground Mezzanine , 1st & 2nd Floor K.I.A.D.B JIgani Bomasandra , Link Road, Bangalore - 562106, India

Vendor Details

Country of origin: India
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