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Megapen Capsule

Ampicillin (250mg)+ Cloxacillin (250mg)

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Megapen Capsule is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Feb 2026 | 05:04 PM (IST)

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General Information

Contains

Ampicillin (250mg)+ Cloxacillin (250mg)

Marketer

Aristo Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Megapen Capsule is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Megapen Capsule

Treatment of Bacterial infections

Benefits of Megapen Capsule

Treatment of Bacterial infections
Megapen Capsule is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Megapen Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megapen

Allergic reaction
Rash
Stomach pain
Nausea
Diarrhea

How to use Megapen Capsule

Take this medicine in the dose and duration as advised by your doctor. Megapen Capsule may be taken with or without food.

How Megapen Capsule works

Megapen Capsule is a combination of two antibiotics: Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.

All substitutes for Megapen Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed this combination medicine to treat bacterial infections.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Megapen Capsule may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Take it with food and plenty of fluids to avoid an upset stomach.
Stop taking Megapen Capsule and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Megapen Capsule.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Megapen Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Megapen Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Megapen Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Megapen Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine.

Liver

CAUTION

Megapen Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is advised while taking this medicine.

Frequently asked questions

How long does Megapen Capsule takes to work?

Usually, Megapen Capsule starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Can I stop taking Megapen Capsule when I feel better?

No, do not stop taking Megapen Capsule and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

What is Megapen Capsule used for?

Megapen Capsule is used to treat patients with bacterial infections. It is a semi-synthetic derivative of the drug penicillin. It is used to treat urinary tract and respiratory tract infections, meningitis, gonorrhea and infections of the stomach or intestine.

Which medicines should be avoided while taking Megapen Capsule?

Megapen Capsule should be avoided with methotrexate which is used to treat rheumatoid arthritis, psoriasis and some forms of cancer. This is because combining the two medications can cause some serious side effects.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Megapen Capsule

Twice A Day

39%

Thrice A Day

30%

Once A Day

25%

Four Times A Day

What are you using Megapen Capsule for?

Bacterial infections

76%

Others

24%

How much was the improvement?

Average

42%

Excellent

39%

Poor

19%

What were the side-effects while using Megapen Capsule?

No Side Effect

56%

Rash

22%

Diarrhea

Stomach pain

Sleepiness

How do you take Megapen Capsule?

With food

64%

With or without food

24%

Empty stomach

12%

Please rate Megapen Capsule on price

Average

43%

Not Expensive

31%

Expensive

26%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Megapen Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Megapen Capsule

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Megapen Capsule

Benefits of Megapen Capsule

Side effects of Megapen Capsule

How to use Megapen Capsule

How Megapen Capsule works

All substitutes for Megapen Capsule

MEGAclox Capsule

Ampoxin 500 Capsule

Danaclox 250mg/250mg Capsule

Allclox 250mg/250mg Capsule

ELCLOX 250MG/250MG CAPSULE

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How long does Megapen Capsule takes to work?

Can I stop taking Megapen Capsule when I feel better?

What is Megapen Capsule used for?

Which medicines should be avoided while taking Megapen Capsule?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

User feedback

Patients taking Megapen Capsule

What are you using Megapen Capsule for?

How much was the improvement?

What were the side-effects while using Megapen Capsule?

How do you take Megapen Capsule?

Please rate Megapen Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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