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MEGAclox Capsule
Ampicillin (250mg)+ Cloxacillin (250mg)
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MEGAclox Capsule is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
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General Information
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Product introduction
MEGAclox Capsule is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of MEGAclox Capsule
Benefits of MEGAclox Capsule
Treatment of Bacterial infections
MEGAclox Capsule is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
MEGAclox Capsule is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Side effects of MEGAclox Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of MEGAclox
- Allergic reaction
- Rash
- Stomach pain
- Nausea
- Diarrhea
How to use MEGAclox Capsule
Take this medicine in the dose and duration as advised by your doctor. MEGAclox Capsule may be taken with or without food.
How MEGAclox Capsule works
MEGAclox Capsule is a combination of two antibiotics: Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed this combination medicine to treat bacterial infections.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect. Taking probiotics along with MEGAclox Capsule may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
- Take it with food and plenty of fluids to avoid an upset stomach.
- Stop taking MEGAclox Capsule and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking MEGAclox Capsule.

Pregnancy
CONSULT YOUR DOCTOR
The safety of MEGAclox Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
MEGAclox Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
CONSULT YOUR DOCTOR
It is not known whether MEGAclox Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
MEGAclox Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine.
Regular monitoring of kidney function tests is advised while taking this medicine.

Liver
CAUTION
MEGAclox Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is advised while taking this medicine.
Regular monitoring of liver function tests is advised while taking this medicine.
Frequently asked questions
Usually, MEGAclox Capsule starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop taking MEGAclox Capsule and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
MEGAclox Capsule is used to treat patients with bacterial infections. It is a semi-synthetic derivative of the drug penicillin. It is used to treat urinary tract and respiratory tract infections, meningitis, gonorrhea and infections of the stomach or intestine.
MEGAclox Capsule should be avoided with methotrexate which is used to treat rheumatoid arthritis, psoriasis and some forms of cancer. This is because combining the two medications can cause some serious side effects.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Related lab tests
References
- Ampicillin+Cloxacillin. Bangalore, India: Medreich Limited; 2014. [Accessed 08 Apr. 2019] (online) Available from:
- ScienceDirect. Cloxacillin. [Accessed 08 Apr. 2019] (online) Available from:
- Ampicillin trihydrate. Egham, Surrey: Chemidex Pharma Ltd.; 2005 [revised 8 Apr. 2015]. [Accessed 10 Apr. 2019] (online) Available from:
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User feedback
Bacterial infections
76%
Others
24%
Excellent
42%
Average
42%
Poor
17%
Vomiting
100%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver MEGAclox Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver MEGAclox Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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