


Mefatol PDS Syrup
Mefenamic Acid (100mg)+ Paracetamol (250mg)
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Mefatol PDS Syrup is a combination of two medicines used in the treatment of fever. It is also useful for the treatment of mild to moderate pain of various conditions like headache, body ache, and toothache. It works by reducing chemical messengers that cause pain, inflammation, and fever.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Aug 2026 | 01:04 AM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Aug 2026 | 01:04 AM (IST)
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Mefatol PDS Syrup
bottle of 60 ml Syrup
₹63.8

Same composition
Macfast Forte Syrup
bottle of 60 ml Syrup
by Macleods Pharmaceuticals Pvt Ltd
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₹56.1
₹0.8 per ml
₹47.7
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₹1200
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General Information
Contains
Mefenamic Acid (100mg)+ Paracetamol (250mg)
Marketer
Optibrex Lifesciences
Storage
Store below 30°C
The content is shown in English



Product introduction
Mefatol PDS Syrup is to be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, and heartburn. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, and heartburn. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcers or bleeding in your stomach, high blood pressure, or any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Uses of Mefatol PDS Syrup
- Pain relief : Mefatol PDS Syrup helps relieve pain in conditions such as headache, body ache, muscle pain, toothache, menstrual cramps, and minor injuries.
- Treatment of Fever : Mefatol PDS Syrup helps reduce fever in conditions such as flu, viral infections, post-vaccination reactions, and other illnesses associated with fever.
Benefits of Mefatol PDS Syrup
Pain relief
Pain can occur due to inflammation or injury affecting different parts of the body. Mefatol PDS Syrup works by blocking chemical messengers responsible for pain and inflammation. This helps reduce discomfort in conditions such as headache, toothache, muscle pain, joint pain, and menstrual cramps. It improves daily functioning and provides effective short-term relief from pain.
Pain can occur due to inflammation or injury affecting different parts of the body. Mefatol PDS Syrup works by blocking chemical messengers responsible for pain and inflammation. This helps reduce discomfort in conditions such as headache, toothache, muscle pain, joint pain, and menstrual cramps. It improves daily functioning and provides effective short-term relief from pain.
Treatment of Fever
Fever is usually a sign of infection or inflammation in the body. Mefatol PDS Syrup helps reduce high temperature by blocking chemical messengers that trigger fever. This brings down body temperature and relieves associated symptoms such as body aches and discomfort.
Fever is usually a sign of infection or inflammation in the body. Mefatol PDS Syrup helps reduce high temperature by blocking chemical messengers that trigger fever. This brings down body temperature and relieves associated symptoms such as body aches and discomfort.
Side effects of Mefatol PDS Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefatol PDS
- Diarrhea
- Nausea
- Hypersensitivity
- Skin rash
How to use Mefatol PDS Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Mefatol PDS Syrup should be taken with or after food.
How Mefatol PDS Syrup works
Mefatol PDS Syrup is a combination of two medicines: Mefenamic Acid and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
All substitutes for Mefatol PDS Syrup
For information purposes only. Consult a doctor before taking any medicine.
Macfast Forte Syrup
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Evamef DS Syrup
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Mefochem P Syrup
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Quick tips
- Take Mefatol PDS Syrup with food to reduce the risk of stomach irritation.
- Avoid taking Mefatol PDS Syrup with other medicines containing paracetamol or other NSAIDs unless advised by your doctor.
- Mefatol PDS Syrup may cause dizziness or sleepiness, so avoid driving or operating machinery until you know how it affects you.
- Stop taking Mefatol PDS Syrup and consult your doctor if you develop diarrhea while using this medicine.
- Watch for warning signs such as severe stomach pain or black/tarry stools, and seek medical attention if they occur.
- Avoid alcohol while taking Mefatol PDS Syrup as it may increase drowsiness and the risk of stomach or liver problems.
- Stay well hydrated while taking Mefatol PDS Syrup, as dehydration may increase the risk of kidney-related side effects.
- Inform your doctor if you develop rash, swelling, or other signs of allergy while taking Mefatol PDS Syrup.
- Do not use Mefatol PDS Syrup for long periods without medical supervision.
- Your doctor may monitor kidney function, liver function, and blood parameters if Mefatol PDS Syrup is used for long-term treatment.
- Inform your doctor if you have a history of kidney disease, liver disease, or stomach ulcers before taking Mefatol PDS Syrup.
- Do not increase the dose or frequency of Mefatol PDS Syrup without medical advice.
- Consult your doctor if pain or fever persists or keeps recurring despite taking Mefatol PDS Syrup.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Mefatol PDS Syrup.

Pregnancy
CONSULT YOUR DOCTOR
Mefatol PDS Syrup is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Mefatol PDS Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Mefatol PDS Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Mefatol PDS Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Mefatol PDS Syrup is not recommended in patients with severe kidney disease.
Use of Mefatol PDS Syrup is not recommended in patients with severe kidney disease.

Liver
UNSAFE
Mefatol PDS Syrup is unsafe to use in patients with liver disease and should be avoided.
However, the use of Mefatol PDS Syrup is not recommended in patients with severe liver disease and active liver disease.
However, the use of Mefatol PDS Syrup is not recommended in patients with severe liver disease and active liver disease.
Frequently asked questions
Mefatol PDS Syrup may cause some common side effects such as nausea, stomach pain, heartburn, or diarrhea. Some people may also experience vomiting or dizziness. These effects often occur because the medicine can irritate the stomach lining. Taking Mefatol PDS Syrup with food or milk may help reduce stomach discomfort. In rare cases, it may cause serious problems such as stomach bleeding or kidney damage. Seek medical attention if you notice warning signs such as black stools, vomiting blood, or severe stomach pain.
Mefatol PDS Syrup is usually prescribed for short-term use to relieve pain. In many cases, it can be stopped once the pain improves. However, if your doctor has advised you to take it for a specific period, you should continue using it for the recommended duration. Always follow your doctor’s instructions before stopping any prescribed medicine.
Mefatol PDS Syrup should be avoided by people who are allergic to this medicine or to other similar pain relievers known as NSAIDs. It is also not recommended for individuals with stomach ulcers, active stomach bleeding, severe liver disease, or serious kidney problems. People who have a history of stomach irritation or bleeding should only take it if advised by a doctor. Always inform your doctor about your medical history and any other medicines you are taking before starting Mefatol PDS Syrup.
Yes, Mefatol PDS Syrup can usually be taken with vitamin B-complex supplements. While Mefatol PDS Syrup helps relieve pain, vitamin B-complex may help correct vitamin deficiencies that could contribute to certain types of pain, such as nerve-related discomfort. However, it is still best to consult your doctor before combining medications or supplements.
Mefatol PDS Syrup may affect the kidneys or liver if it is used for a long time or taken in higher-than-recommended doses. The medicine can reduce protective substances that help maintain kidney function, which may lead to kidney damage. Misuse or combining it with other medicines containing similar ingredients may also strain the liver. The risk is higher in people who already have kidney or liver disease. Always take Mefatol PDS Syrup only as prescribed and avoid unnecessary or prolonged use.
No, taking more than the recommended dose of Mefatol PDS Syrup can increase the risk of side effects such as nausea, vomiting, indigestion, heartburn, and diarrhea. Overuse may also harm the kidneys, especially with long-term use. If your pain is severe or not relieved by the prescribed dose, consult your doctor instead of increasing the dose on your own.
Mefatol PDS Syrup is a medicine used for short-term relief of pain and fever. It is commonly prescribed for menstrual cramps (period pain), dental pain, headaches, muscle or joint pain, and general body aches. It works by reducing certain substances in the body that cause pain, inflammation, and fever. While it helps relieve symptoms, it does not treat the underlying cause of the pain. Always take Mefatol PDS Syrup exactly as directed by your doctor and avoid long-term or unnecessary use.
Mefatol PDS Syrup is generally not recommended during pregnancy unless your doctor specifically advises it. Anti-inflammatory pain medicines can affect pregnancy and the baby, especially during the later stages. Mefenamic acid may affect the baby’s circulation and kidney function later in pregnancy and may also increase bleeding risk. If you are pregnant, think you may be pregnant, or are planning pregnancy, consult your doctor before taking Mefatol PDS Syrup.
It is best to avoid alcohol while taking Mefatol PDS Syrup. Alcohol can increase the risk of stomach irritation and bleeding, and it may also add stress to the liver when combined with certain pain medicines. If you drink alcohol regularly, discuss this with your doctor before taking Mefatol PDS Syrup.
The active ingredient in Mefatol PDS Syrup, mefenamic acid, is gradually cleared from the body, although the exact time can vary depending on factors such as age, liver and kidney function, and hydration. Even after the medicine starts leaving the body, stomach irritation or bleeding risk may persist for some time. If you are planning surgery or have kidney problems, inform your doctor that you have taken Mefatol PDS Syrup so they can advise you appropriately.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Related lab tests
References
- FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
- ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
- ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:
- Paracetamol and Mefenamic acid. Centaur; [Accessed 16 Jan. 2026] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Optibrex Lifesciences
Address: 351, 2nd Floor, Industrial Area, Phase-2, Panchkula-134113
Address: 351, 2nd Floor, Industrial Area, Phase-2, Panchkula-134113
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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