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Mefanic DS Syrup

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 16 Mar 2026 | 02:53 AM (IST)
Mefanic DS Syrup is a combination of two medicines. It is used in the treatment of fever. It is also useful for the treatment of mild to moderate pain of various conditions like headache, body ache, and toothache.
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General Information

Contains

Mefenamic Acid (250mg/5ml)+ Paracetamol (100mg/5ml)

Marketer

Glydus Remedies Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Mefanic DS Syrup image
Mefanic DS Syrup image

Your child’s medicine at a glance

Mefanic DS Syrup is to be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, and heartburn. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of Mefanic DS Syrup in children

Benefits of Mefanic DS Syrup for your child

Pain relief
Mefanic DS Syrup is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches.
Treatment of Fever
Mefanic DS Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Mefanic DS Syrup in children

Mefanic DS Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Mefanic
  • Vomiting
  • Diarrhea
  • Nausea
  • Indigestion
  • Loss of appetite
  • Heartburn

How can I give Mefanic DS Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Mefanic DS Syrup should be taken with or after food.

How Mefanic Syrup works

Mefanic DS Syrup is a combination of two medicines: Mefenamic Acid and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick tips

  • Mefanic DS Syrup is used to reduce pain and swelling in various conditions.
  • Take it with food to prevent an upset stomach.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • If you get diarrhea while taking this medicine, stop taking it and consult your doctor.
  • Avoid consuming alcohol while taking Mefanic DS Syrup as it can cause excessive drowsiness and increase your risk of stomach problems.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. 

Safety advice

Kidney

Kidney

CAUTION
Mefanic DS Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Mefanic DS Syrup is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Mefanic DS Syrup is unsafe to use in patients with liver disease and should be avoided.
However, the use of Mefanic DS Syrup is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Yes, Mefanic DS Syrup is safe to use in most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem due to the medication.
Mefanic DS Syrup is usually used for short term and can be discontinued when the pain is relieved. However, if advised by the doctor, it should be continued for the recommended time period.
Yes, the use of Mefanic DS Syrup can cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with the medicine. In the case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to the doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Yes, the use of Mefanic DS Syrup can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.
The use of Mefanic DS Syrup is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcer or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of liver or kidney disease.
Yes, Mefanic DS Syrup can be taken with Vitamin B-complex preparations. While Mefanic DS Syrup helps to relieve pain, Vitamin B-complex can help correct the vitamin deficiency that might be causing the underlying painful condition.
Yes, the long-term use of Mefanic DS Syrup can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
No, taking a higher than the recommended dose of Mefanic DS Syrup can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage the kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Related lab tests

Complete Blood Count

References

  1. FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
  2. ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:
  4. Paracetamol and Mefenamic acid. Centaur; [Accessed 16 Jan. 2026] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glydus Remedies Pvt Ltd
Address: L-403, Anand Vihar,Tragadgam Chankheda Ahmedabad Gujrat 382470

Vendor Details

Country of origin: India

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