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Markold DS Syrup

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 14 Nov 2025 | 11:54 AM (IST)
Markold DS Syrup is used in the treatment of common cold and cough associated with fever in children. It provides relief from pain and fever and helps treat cough and common cold symptoms like runny nose, stuffy nose, and sneezing.
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The content is shown in English
Markold DS Syrup image
Markold DS Syrup image

Product introduction

Markold DS Syrup may be given to your child with or without food. Give it in a dose and duration as advised by the doctor. The dose and duration of the treatment will depend on your child’s condition and how they respond to the medicine. Continue to administer the medicine for as long as the doctor has recommended.


The most common side effects are nausea and headache. Most of these are temporary and usually resolve with time. Contact the doctor straight away if you are at all concerned about any of these side effects experienced by the child. This medicine can also cause sleepiness, so do not let your child do anything that requires mental focus until you know how this medicine affects them.


It is beneficial to have plenty of fluids while taking Markold DS Syrup. Before giving the medicine to your child, let your doctor know if they have any kidney or liver diseases so that your doctor can prescribe a suitable dose for the child.

Uses of Markold Syrup

Benefits of Markold Syrup

Treatment of Dry cough
A dry cough, also known as non-productive cough, is a cough where no phlegm or mucus is produced. This is irritating, usually associated with a tickly throat and may be caused due to cold, flu, allergies or throat irritants. Markold DS Syrup suppresses dry, hacking coughs. It will also relieve allergy symptoms like watery eyes, sneezing, runny nose or throat irritation. This medicine can provide a quick relief and the effects can last up to several hours.
Common cold
Markold DS Syrup effectively relieves symptoms associated with common cold in children, such as fever, blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier. Markold DS Syrup usually starts working within a few minutes, and the effects can last up to several hours.

Side effects of Markold Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Markold
  • Tachycardia
  • Palpitations
  • Dizziness
  • Fear
  • Restlessness
  • Weakness
  • Discomfort when urinating
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Convulsion
  • Anxiety
  • Tremors
  • Headache
  • Hallucination
  • Sedation

How to use Markold Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Markold DS Syrup may be taken with or without food.

How Markold Syrup works

Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that cause pain and fever. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Sodium Citrate is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Menthol is an organic compound which produces a sensation of coolness and relieves minor throat irritation.

All substitutes for Markold DS Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Markold DS Syrup helps relieve symptoms of cold and flu such as headache, sore throat, runny nose, muscular pain, and fever.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Markold DS Syrup helps relieve symptoms of cold and flu such as headache, sore throat, runny nose, muscular pain, and fever.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Markold DS Syrup
Pregnancy

Pregnancy

UNSAFE
Markold DS Syrup is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Markold DS Syrup during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Markold DS Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Markold DS Syrup is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

SAFE IF PRESCRIBED
Markold DS Syrup is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Frequently asked questions

Markold DS Syrup is a combination medicine containing paracetamol, phenylephrine, chlorpheniramine maleate, sodium citrate, and menthol. It is mainly used to relieve symptoms of the common cold, such as blocked nose, runny nose, sneezing, sore throat, cough, and mild fever.
Although they are rare, serious side effects of Markold DS Syrup may include liver damage, severe skin reactions like Stevens-Johnson syndrome, difficulty in breathing, rapid heartbeat, hallucinations, or convulsions. If any of these occur, medical help should be sought immediately.
Markold DS Syrup should not be used in children or adults who are allergic to any of its ingredients, have severe high blood pressure, serious liver or kidney problems, heart disease, or glaucoma. It must also be avoided if the patient is currently taking medicines called monoamine oxidase inhibitors (MAOIs).
Markold DS Syrup is usually prescribed for children between 2 and 12 years old, but the dose depends on age and body weight. It should not be given to children below 2 years unless advised by a doctor. Always follow the pediatrician’s dosage instructions carefully to prevent overdose.
Markold DS Syrup already contains multiple active ingredients for cold and flu relief. Taking it along with other cough and cold medicines, especially those containing paracetamol or antihistamines, can increase the risk of overdose and serious side effects.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Elixir Life Care Pvt Ltd
Address: No: 260, Sydenhams Road, Choolai, Chennai - 600112, India

Vendor Details

Country of origin: India
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