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Malacure 80mg Drop

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Malacure 80mg Drop is an anti-parasitic medicine. It is given to prevent and treat malaria caused by a mosquito bite. Additionally, it may also be used to treat bowel infections in children that are caused by another type of parasite (amoeba).
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General Information

The content is shown in English
Malacure 80mg Drop image
Malacure 80mg Drop image

Your child’s medicine at a glance

Give Malacure 80mg Drop to your child by mouth, preferably after meals to prevent an upset stomach. Do not give antacids within 4 hours of taking this medicine as they may interfere with the absorption of the medicine. Malacure 80mg Drop can be slightly bitter. You can mix it with fruit juices to mask the bitterness. If your child vomits soon after taking Malacure 80mg Drop, help the child calm down and repeat the same dose after half an hour. However, skip the dose if it's time for the next dose. Do not double up the dose to catch up for the missed one.

Give it as per the dose, time, and way prescribed by the doctor as that is based on factors such as your child's weight, age, clinical condition, and treatment response. Malacure 80mg Drop may be given in higher doses for the initial one or two days followed by low doses in subsequent days. Strictly follow the dosing schedule prescribed by your child’s doctor as prolonged use of Malacure 80mg Drop can cause serious side effects in your child.

Malacure 80mg Drop may cause side effects such as headache, nausea, loss of appetite, diarrhea, upset stomach, stomach pain, rash, itching, hair loss, or increased sensitivity to light. These are usually temporary. However, if these persist, seek your doctor’s help.

Let the doctor know about your child’s complete medical history including history of any allergies and ongoing medicine regimen. The doctor must be informed about any previous complications related to liver, kidney, brain, heart, muscle weakness, genetic problems, blood cell abnormalities, or ear and eye problems. This information plays a critical role in planning your child’s overall treatment.

Uses of Malacure 80mg Drop in children

Benefits of Malacure 80mg Drop for your child

Treatment of Malaria
Malacure 80mg Drop is used to treat malaria, a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. It kills the infection causing parasite and stops further spread of the infection. Take it only as prescribed and refrain from taking any other medicines along with this medicine (unless advised by the doctor) as they may affect the absorption of this medicine. Do not use this medicine for treating any other condition without consulting your doctor.
Treatment of Amoebiasis
Amoebiasis is an infection caused by a parasite named Entamoeba histolytica. It is often transmitted through contaminated food or water. Symptoms associated with Amoebiasis are not very common. However, in some cases where symptoms do occur, the severity may range from mild diarrhea to blood in stools (dysentery), intestinal inflammation, and pus in the liver (liver abscess). Malacure 80mg Drop is given along with other medicines for the treatment of the above manifestations. Awareness of the quality of food, water, and sanitation conditions can help to prevent an infection.

Side effects of Malacure 80mg Drop in children

Malacure 80mg Drop does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Malacure
  • Nausea
  • Stomach pain
  • Loss of appetite
  • Rash
  • Headache
  • Dizziness
  • Vomiting
  • Upset stomach
  • Photosensitivity
  • Diarrhea

How can I give Malacure 80mg Drop to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Malacure 80mg Drop should be taken with or after food.

How Malacure Drop works

Malacure 80mg Drop is an antiparasitic medication that is used to treat Malaria and Amoebiasis. It works by increasing the levels of heme and pH in the red blood cells where the parasite resides. It also acts by directly interfering with the genetic material of malarial parasites, thereby killing the parasite and stopping the infection from spreading.

Quick tips

  • When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.
  • Take Malacure 80mg Drop with food to decrease the risk of stomach upset.
  • Malacure 80mg Drop may make your child sensitive to sunlight. Take special care and use protective gear when your child is outdoors.
  • Some self-care measures:
    1. Use of mosquito repellent creams, liquids, coils, mats, etc.
    2. Do not let water accumulate in the house as it may lead to mosquito breeding.  Instead, you can put a small amount of Kerosene oil in the water. This floating oil helps to trap and kill mosquito larvae and dramatically reduce mosquito breeding.
    3. Screen the houses with wire mesh.
    4. Use bed nets at home while sleeping.
    5. Wear clothes that cover the maximum surface area of the body.
    6. Avoid spraying insect repellents on children. Lower their evening and night-time outdoor activity.
  • When used long-term, the doctor may monitor the amounts of the different types of blood cells in your child’s blood regularly. Inform your doctor if you notice unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness in your child.
  • Consult your doctor immediately if your child exhibits serious side effects such as rash, swollen glands, problems with body organs like liver, kidney, or heart.
  • Keep Malacure 80mg Drop away from children. Accidental exposure may cause serious events. If a child takes this medicine by accident, get medical help right away.
  • If your child develops a fever while in or after leaving a high-risk area, call the doctor right away.
  • Malacure 80mg Drop is used for the prevention and treatment of malaria.
  • Take it with food to decrease the risk of stomach upset.
  • Tips to reduce the chance of being bitten by mosquitoes:
    • Wear light-colored and covered clothing when you are outside after sunset.
    • Use insect repellent creams or sprays on parts of your body not covered by clothing.
    • Spray to kill any mosquitoes that may have entered rooms despite screening.
  • It may cause a blurring of vision when you first start taking it. Use caution while driving or doing anything that requires concentration.
  • Eye examination before and at 3–6 monthly intervals during use is required if patients are receiving Malacure 80mg Drop at continuous high doses for a longer duration.
  • It may cause low blood sugar levels. Monitor your blood sugar level regularly, if you are diabetic.
  • When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.

Safety advice

Kidney

Kidney

SAFE IF PRESCRIBED
Malacure 80mg Drop is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, prolonged use may impact kidney function in your child. The use of this medicine is not recommended in children with severe kidney disease.
Liver

Liver

CAUTION
Malacure 80mg Drop should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Malacure with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Leflunomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Severe

Sevoflurane (Inhalation Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Teriflunomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Severe

Remdesivir (Injection Route)

Do not consume Remdesivir with Chloroquine. Chloroquine may reduce the efficacy of Remdesivir.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Your child needs to undergo laboratory tests such as complete blood count, blood smear test, or malaria rapid diagnostic test for the diagnosis of malaria.
Children with G-6-PD enzyme deficiency should avoid Malacure 80mg Drop. The deficiency of this enzyme in the body can lead to the breaking of blood cells, resulting in severe anemia. It is advised that you get your child’s enzyme level evaluated before starting the course of treatment.
Malacure 80mg Drop may interact with other medicines or substances. Therefore, it would be advised to inform your doctor about any other medicines your child is taking before starting Malacure 80mg Drop.
Malacure 80mg Drop should be stored at room temperature in a dry place, away from direct heat and light. Also, keep all medicines out of the reach and sight of children to avoid any mishap.
Malacure 80mg Drop is an anti-malarial medicine that is used for the treatment and prevention of malaria.
Symptoms of malaria can develop as quickly as 7 days after you are bitten by an infected mosquito. Usually, the symptoms may take up to 7 to 18 days to appear (incubation periods) from the day of the infection. Initial symptoms of malaria are flu-like which include feeling hot and shivery, fever, muscle pains, vomiting, headaches, and diarrhea.
If your doctor has prescribed you Malacure 80mg Drop for a longer period of time, you should get your eyes checked regularly. This is because chloroquine present in this medicine might cause blurred vision, difficulty reading (due to words disappearing), and a rare eye condition called retinopathy if taken for a longer period of time.
Inform your doctor if you have psoriasis before taking Malacure 80mg Drop since it may make your condition worse.
Some of the most common side effects of this medicine are stomach pain, nausea, vomiting, and headache. These side effects can often be reduced by taking the medicine with food.
There is not enough medical data to prove that chloroquine is effective in treating COVID-19. Therefore it is advisable not to take Malacure 80mg Drop without consulting your doctor for treating COVID-19.
If you take an antacid, give a gap of at least 4 hours between the two medications.
Hydroxychloroquine and chloroquine were both first approved for malaria. However, chloroquine tends to cause many more side effects than hydroxychloroquine. As a result, hydroxychloroquine is more commonly used today. Hydroxychloroquine is also approved to treat rheumatoid arthritis and lupus, while chloroquine is not.
Malaria can be prevented by taking certain precautionary steps like covering your arms and legs to prevent mosquito bites, using a mosquito net and insect repellent. Check with your doctor whether you need to take malaria prevention tablets. If you do, make sure you take the right antimalarial tablets at the right dose and finish the proper course of treatment.

Fact Box

Chemical Class

4- aminoquinolines

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Antimalarial- Aminoquinolines

References

  1. Vinetz JM, Clain J, Bounkeua V, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1402-405.
  2. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 630.
  3. Rosenthal PJ. Antiprotozoal Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 901-904.
  4. Memorial Sloan Kettering: Cancer Center. Chloroquine. [Updated 07 Jun. 2021]. [Accessed 14 Jun. 2021] (online) Available from:
  5. C.S. Mott Children's Hospital. Chloroquine. [Accessed 14 Jun. 2021] (online) Available from:
  6. Medline Plus. Chloroquine. [Revised - 15 Oct. 2020]. [Accessed 14 Jun. 2021] (online) Available from:
  7. Drug Bank. Chloroquine. [Accessed 14 Jun. 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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