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Composition FOR LOMTIN

Lomustine(40 mg)

food interaction for LOMTIN

alcohol interaction for LOMTIN

pregnancy interaction for LOMTIN

lactation interaction for LOMTIN

It is better to take Lomtin 40mg capsule empty stomach (1 hour before food or 2 hours after food).
Interaction with alcohol is unknown. Please consult your doctor.
Lomtin 40mg capsule is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Lomustine(40 mg)


Lomtin 40mg capsule is used in the treatment of malignant melanoma, Hodgkin’s disease (a cancer of the lymph glands), brain tumor and lung cancer

How it works

Lomtin 40mg capsule works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Rash, Reduced blood platelets, Headache, Dizziness, Convulsion, Myelosuppression, Decreased urination, Coordination disorder, Increased magnesium level in blood, Shortness of breath, Insomnia, Mouth ulcer, Vomiting, Weakness, Sleepiness, Nausea, Decreased potassium level in blood, Abdominal pain, Persistent dry cough, Infection, Slurred speech, Loss of appetite, Bone-marrow suppression, Brain swelling, Decreased white blood cell count, Cns toxicity, Hair loss, Fatigue, Fever, Anxiety, Increased liver enzymes, Anemia, Hallucination, Thrombophlebitis, Diarrhoea, Blood in urine, Depression, Vertigo, Speech disorder, Confusion, Mucosal inflammation, Drowsiness, Gastritis, Decreased white blood cell count (neutrophils), Constipation, Stomatitis, Hemiparesis (weakness on one side of the body), Uncoordinated body movements, Decreased white blood cell count (lymphocytes), Viral infection, Increased glucose level in blood, Walking difficulties


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Expert advice FOR LOMTIN

  • Take lomustine as recommended by your doctor preferably on empty stomach.
  • Take precautions as lomustine is known to lower the white blood cells and platelets in blood that will make you more prone to infections or you may bleed easily/excessively.
  • Seek immediate medical attention if you observe signs of infections such as fever, chills, body ache or if you have unusual bruising or bleeding.
  • Do not receive any live vaccines [for eg. measles, mumps, MMR (Rubella), rotavirus, typhoid, yellow fever, chickenpox, zoster and influenza vaccine] while on lomustine treatment.
  • Use disposable gloves while handling lomustine capsule to avoid direct contact with medicine.
  • Use appropriate contraceptive measures while on lomustine treatment.
  • Men are advised not to father children during treatment with lomustine and for up to 6 months afterwards, and should seek advice regarding sperm conservation before the start of treatment with lomustine, as there is a chance that lomustine may cause permanent infertility in men.
  • You may need to undergo frequent blood tests and kidney/lung/liver function tests to evaluate drugs effect on your body.
  • Contact your doctor if you observe severe side effects such as chest discomfort, difficulty breathing, rapid heart rate, dry cough, wheezing, reduced/no urination, yellowing of skin and eyes (jaundice), pale skin, inability to concentrate.

Frequently asked questions FOR LOMTIN



Is lomustine effective?
Lomustine is effective if taken as per the dose and for the duration prescribed by a doctor. It may be used in combination with other drugs/radiotherapy or surgery to get best results. Follow your doctor's instructions about this treatment carefully


How fast does lomustine work?
Lomustine treatment includes administration of medicine in several sessions/cycles. Each cycle of lomustine is usually a single oral dose given every 6-8 weeks. Duration of treatment may depend upon the type of cancer and body's response to the medicine. Total treatment with lomustine may run over a few months


How long does lomustine stay in the body?
Lomustine may stay in body from 16 hours to 2 days.


Content on this page was last updated on 03 February, 2017, by Dr. Varun Gupta (MD Pharmacology)