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Lomotil Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 10 Mar 2026 | 11:05 AM (IST)
Lomotil Tablet is a combination medicine used in the treatment of diarrhea. It manages the symptoms of diarrhea such as stomach pain, cramps, and loose stools.
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General Information

Contains

Diphenoxylate (2.5mg)+ Atropine (0.025mg)

Marketer

RPG Life Sciences Ltd

Storage

Store below 25°C
The content is shown in English
Lomotil Tablet image
Lomotil Tablet image
Lomotil Tablet image
Lomotil Tablet image

Product introduction

Lomotil Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are indigestion, constipation, dryness in mouth, cough, flushing of skin, blurred vision, confusion, difficulty in urination, and bronchoconstriction (constriction of air passages). Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. To overcome constipation, you should add fiber-rich foods in your diet and stay hydrated. It may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. Consult your doctor immediately if you experience any allergic reactions such as skin rash, swelling, and itching.

Uses of Lomotil Tablet

Benefits of Lomotil Tablet

Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Lomotil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lomotil
  • Indigestion
  • Constipation
  • Dryness in mouth
  • Cough
  • Flushing of skin
  • Blurred vision
  • Drowsiness
  • Dizziness
  • Confusion
  • Difficulty in urination
  • Bronchoconstriction (constriction of air passages)

How to use Lomotil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lomotil Tablet may be taken with or without food.

How Lomotil Tablet works

Lomotil Tablet is a combination of two medicines:

Quick tips

  • You have been prescribed Lomotil Tablet for the treatment of diarrhea.
  • Diarrhea can cause water loss and electrolyte imbalance. Drink plenty of fluids especially ORS (oral rehydration solution) to help keep you hydrated.
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Lomotil Tablet if you have blood in your stool or if you are severely constipated.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lomotil Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Lomotil Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Lomotil Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Lomotil Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Lomotil Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Lomotil Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Yes, the use of Lomotil Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.
Yes, the use of Lomotil Tablet can cause constipation. Talk to your doctor if constipation occurs.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Yes, the use of Lomotil Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
No, avoid drinking alcohol while taking Lomotil Tablet. Drinking alcohol will increase the severity of drowsiness and sleepiness caused by Lomotil Tablet.

Fact Box

Habit Forming

Yes

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Stool Examination R/M

References

  1. MedlinePlus. Diphenoxylate. [Accessed 14 Feb. 2019] (online) Available from:
  2. Centre for Food Safety, Hong Kong. Atropine and Scopolamine in Foods. [Accessed 14 Feb. 2019] (online) Available from:
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User feedback

Once A Day
100%
Diarrhea
95%
Others
5%
Excellent
50%
Average
45%
Poor
5%
No Side Effect
33%
Dryness in mouth
22%
Arrhythmia (irregular heartbeats)
11%
Excessive thirst
11%
Constipation
11%
With food
88%
Empty stomach
12%
Not Expensive
46%
Expensive
33%
Average
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: RPG Life Sciences Ltd
Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

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