LinVAS Tablet is used in people with Type 2 diabetes mellitus who have abnormal lipid levels. It helps manage diabetic dyslipidemia and high triglycerides when statins alone are not sufficient.
LinVAS Tablet may be taken with or without food, at the same time each day, to get the most benefit and you should not stop taking it unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in maintaining a healthy body weight, which will help protect your liver to a great extent.
The most common side effects of this medicine are flatulence, indigestion, abdominal distension, increased body temperature, and weakness. These are usually not severe. Please consult your doctor if the side effects worry you or if they do not go away.
Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can degrade your liver health. You may need regular tests such as liver function test, kidney function and blood glucose levels to check that the medicine is working properly.
In Diabetic dyslipidemia (high cholesterol in diabetes)
In people with Type 2 diabetes mellitus, it is common to have abnormal cholesterol levels, especially high triglycerides, a condition known as diabetic dyslipidemia. LinVAS Tablet helps reduce elevated triglycerides and improves overall lipid balance in such cases where statin therapy alone does not provide adequate control. This supports better management of lipid levels and may help lower the risk of complications associated with uncontrolled cholesterol in diabetes.
Side effects of LinVAS Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of LinVAS
Gastritis
Headache
Weakness
Fever
Flatulence
Indigestion
Abdominal distension
How to use LinVAS Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. LinVAS Tablet may be taken with or without food.
How LinVAS Tablet works
LinVAS Tablet contains Saroglitazar, a dual action peroxisome proliferator-activated receptor (PPAR) inhibitor that aids in the management of high cholesterol, especially triglycerides, as well as blood sugar levels in people with type 2 diabetes. It acts by a unique mechanism in which it reduces the synthesis and secretion of triglycerides (a type of lipid or cholesterol in blood). It also improves insulin sensitivity of the body for better utilization of the existing insulin and hence lowers the blood sugar levels.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with LinVAS Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of LinVAS Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of LinVAS Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
LinVAS Tablet may cause side effects that could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of LinVAS Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
LinVAS Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take LinVAS Tablet?
If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and take it at the next scheduled time. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
It is better to take LinVAS Tablet after a meal or with a snack to avoid stomach problems.
Your doctor may check your liver function before starting the treatment and regularly thereafter.
It is important that you keep your regular appointments with your doctor so your condition can be monitored.
Lifestyle changes like a low-fat and sugar diet, exercise, losing weight, not smoking, and cutting down on the amount of alcohol you normally drink may help this medication work better.
Fact Box
Chemical Class
Phenylpyrroles
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
PPAR Alpha & Gamma Agonists
FAQs
Is there a chance of weight gain with LinVAS Tablet?
It has been observed from clinical research conducted on LinVAS Tablet that there is no significant risk of weight gain in patients taking LinVAS Tablet. However, if a patient experiences a rapid increase in weight, any other difficulty, or fluid accumulation in the body then it should be immediately informed to the doctor for further assessment or change of therapy.
Is LinVAS Tablet is helpful in increasing good cholesterol?
Yes, it has been found that LinVAS Tablet helps improve the good cholesterol or HDL-C and at the same time helps reduce the bad cholesterol like LDL, triglycerides etc. Though the effectiveness of this medicine varies from patient to patient still it has been found to be effective in controlling the high triglyceride levels in the blood. Consult your doctor before you start taking this medication.
Who should not take LinVAS Tablet?
LinVAS Tablet should not be taken by people who are allergic to LinVAS Tablet or any of its ingredients. If you are not sure, please consult your doctor.
What other lifestyle changes should I make to manage nonalcoholic steatohepatitis (NASH)
Lifestyle changes play a major role in managing nonalcoholic steatohepatitis (NASH). A healthy body weight helps you manage this condition very effectively. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life as it increases body weight too. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels. Stop smoking and alcohol consumption. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of LinVAS Tablet and to keep yourself healthy.
Can I take LinVAS Tablet in pregnancy?
There is no clarity on the use of LinVAS Tablet in pregnancy and it may be unsafe to take it in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking LinVAS Tablet. You may take it only if prescribed by your doctor.
Is it safe for lactating mothers to take LinVAS Tablet?
No, it is not safe for lactating mothers to take LinVAS Tablet because there is no evidence of its safety for usage during breastfeeding. The other reason for not using this medicine is that it is not known whether LinVAS Tablet gets excreted via breast milk. Consult your doctor before taking this medicine if you are breastfeeding to make sure there is no harm to your baby.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Rajesh NA, Drishya L, Ambati MMR, Narayanan AL, Alex M, R KK, Abraham JJ, Vijayakumar TM. Safety and Efficacy of Saroglitazar in Nonalcoholic Fatty Liver Patients With Diabetic Dyslipidemia-A Prospective, Interventional, Pilot Study. J Clin Exp Hepatol. 2022 Jan-Feb;12(1):61-67. [Accessed 06 Aug. 2023] (online) Available from:
Padole P, Arora A, Sharma P, et al. Saroglitazar for Nonalcoholic Fatty Liver Disease: A Single Centre Experience in 91 Patients. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):435-439. [Accessed 06 Aug. 2023] (online) Available from:
Padole P, Arora A, Sharma P, et al. Saroglitazar for Nonalcoholic Fatty Liver Disease: A Single Centre Experience in 91 Patients. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):435-439. [Accessed 06 Aug. 2023] (online) Available from:
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