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Saroglitazar is used in the treatment of dyslipidemia (abnormal lipid levels) and hypertriglyceridemia (increased triglyceride levels) associated with type 2 diabetes mellitus that is not controlled by statin therapy.

How it works

Saroglitazar belongs to a class of medication called PPAR (peroxisome proliferator activated receptor) agonists. It works by reducing triglycerides, very low and low density lipoprotein, and increasing HDL cholesterol. It also has favourable effects on glycemic indices by reducing fasting glucose and glycosylated haemoglobin in patients with diabetes.

Common side effects

Fever, Gastritis, Weakness


Expert advice

  • Use with caution if you have a history of liver or kidney problems, or history of myopathies, heart disease with episodic congestive heart failure or if you observe excessive weight gain.
  • If you have type 2 diabetes with episodic congestive heart failure, you should be regularly monitored for signs and symptoms of congestive heart failure.
  • It should be used with caution in elderly patients.
  • Saroglitazar is not recommended in children.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)