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    Information about Saroglitazar

    Saroglitazar uses

    Saroglitazar is used in the treatment of Diabetic dyslipidemia (high cholesterol in diabetes).

    How saroglitazar works

    Saroglitazar has dual action. It lowers high blood triglycerides as well as blood sugar, and improves the insulin resistance.

    Common side effects of saroglitazar

    Weakness, Fever, Gastritis
    Content Details
    Written By
    Dr. Betina Chandolia
    MDS, BDS
    Reviewed By
    Dr. Lalit Kanodia
    MD (Pharmacology), MBBS
    Last updated on:
    25 Oct 2019 | 10:29 AM (IST)
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    Available Medicine for Saroglitazar

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    Expert advice for Saroglitazar

    • Saroglitazar has beneficial effects in controlling both high cholesterol mainly triglycerides and sugar levels in diabetic patients.
    • It is best to take Saroglitazar before the first meal of the day.
    • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Saroglitazar.

    Frequently asked questions for Saroglitazar


    Q. Is it safe to take Saroglitazar in pregnant and lactating mothers?

    No, it is not safe to take Saroglitazar during pregnancy and lactation because there is no evidence of its safety for usage in pregnant mothers. The other reason for not using this medicine is that it is not known whether Saroglitazar gets excreted via breast milk. Consult your doctor immediately if you become pregnant while taking Saroglitazar and strictly follow the prescribed instructions.

    Q. Is there a chance of weight gain with Saroglitazar?

    It has been observed from a clinical research conducted on Saroglitazar that there is no significant risk of weight gain in patients of diabetes with deranged cholesterol levels. However, if a patient experiences a rapid increase in weight, any other difficulty, or fluid accumulation in the body then it should be immediately informed to the doctor for further assessment or change of therapy.

    Q. Is Saroglitazar is helpful in increasing good cholesterol?

    Yes, it has been found that Saroglitazar helps improve the good cholesterol or HDL-C and at the same time helps reduce the bad cholesterol like LDL, triglycerides etc. Though the effectiveness of this medicine varies from patient to patient still it has been found to be effective in controlling the high triglyceride levels in the blood. Consult your doctor before you start taking this medication.

    Q. Can Saroglitazar be an alternative medicine for glimepiride in treatment of diabetes?

    No, Saroglitazar can’t be used as an alternative for glimepiride. Saroglitazar helps in controlling the blood sugar levels in diabetes and also helps in reducing the cholesterol levels in the blood. It acts by a unique mechanism in which it reduces the synthesis and secretion of triglycerides which are a type of lipid or cholesterol in blood. It also acts by improving insulin sensitivity of the body for better utilization of the existent insulin and hence lowering the blood sugar. Whereas, glimepiride directly acts on the pancreas to increase insulin release and is effective in reducing the blood sugar levels more effectively. Consult your doctor before you take this medication and do not replace or alter it with any other medication.

    Content on this page was last updated on 25 October, 2019, by Dr. Varun Gupta (MD Pharmacology)