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18 Feb 2020 | 05:25 PM (IST)
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Limbitrol H 12.5 mg/5 mg Tablet


Overview

Introduction

Limbitrol H 12.5 mg/5 mg Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Limbitrol H 12.5 mg/5 mg Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Limbitrol H Tablet

  • Depression

Side effects of Limbitrol H Tablet

Common
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movements
  • Depression
  • Memory impairment

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Difficulty in urination
    Relax when you try to pee. Don't try to force the flow of urine. If it doesn't happen, try again later. Limit drinks that increase urination such as coffee, tea and other caffeinated beverages. Continue to drink plenty of water each day. Gentle massage and hot compression on your lower abdomen can help relax your muscles and may improve your urine flow. Doing exercises that strengthen the bladder muscles such as pelvic exercise will be of help. Distract your attention by thinking about something else. Avoid alcohol and smoking because both can aggravate the condition. Talk to your doctor urgently if you can not pee at all.
  • Coping with Weight gain
    Try to eat a healthy balanced diet without increasing your portion sizes. Avoid processed meat or poultry and seafood. Eat small, frequent meals and eat slowly. Do not snack on foods that contain a lot of calories such as crisps, cakes, biscuits and sweets. If you feel hungry between meals, eat fruits and vegetables which have low calories. Avoid reaching for a sugary drink if you feel stressed. Fasting once a week can be an effective way to lose weight. Make sure you get enough sleep. With proper diet and lifestyle changes, you might not gain any weight or may gain only a small amount. Even then if it bothers you, ask your doctor if there are any alternative medicines that do not have this side effect.
  • Coping with Confusion
    If this medicine makes you feel this way, stop what you are doing and sit or lie down until you feel better. If the feeling does not go away or troubles you, do not take any more medicine and speak to a pharmacist or your doctor.
  • Coping with Tiredness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Blurred vision
    You can consider washing your eyes with water. Avoid driving or using tools or machines if your vision is impaired. Do not take your next dose if your vision is still blurry. If it gets worse or does not improve, ask your doctor to recommend eye drops or talk about changing your medications.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Increased heart rate
    Breathe in slowly through your nostrils and then breathe out through your mouth. Repeat this until you feel calm. Try sitting cross-legged and drink plenty of water. Splash cold water or apply a cold towel or ice pack on your face for 20-30 seconds. It is important to make sure that you are not taking more than the prescribed dose. As a preventive measure, you should limit the amount of alcohol you drink and give up smoking. Also, cut down the amount of coffee, tea or cola you drink. In general, being physically active and eating a healthy well-balanced diet is good advice for any heart condition. If the condition does not improve, consult your doctor as they may need to change you to a different type of medicine.
  • Coping with Depression
    It is important to talk to your doctor if you think you may be depressed. The sooner you do this, the sooner you can recover. Treatment for depression can involve a combination of lifestyle changes, talking therapies (such as counseling and cognitive behavioral therapy) and medicines (antidepressants). There are many things you can do for yourself if your depression is not too severe. Exercise is an extremely effective treatment for depression, so make sure you keep as active as possible. It can really lift your mood. A healthy diet can also make a big difference to your mood (as well as improving your physical health). Mindfulness is a technique that many people find helpful. It may be tempting to smoke or drink alcohol, but both will make things worse in the long run. Try talking to a friend or family member even if you do not feel comfortable doing this. Get into a routine with regular sleep patterns and meals. If you have thoughts of self-harm or suicide, contact your doctor immediately.
  • Coping with Memory impairment
    There is a lot you can do to improve your memory. Keep active and take regular exercise to improve blood flow to your whole body, including your brain. Eat a healthy diet so your brain gets the nutrients it needs. Some foods containing omega-3 fatty acids (such as oily fish) may benefit brain health. Keep mentally active. It is important to socialize, so stay in contact with friends and family. Stay organised – keep a diary for things you have to do, keep things you need regularly (such as keys, purse and spectacles) in a set place and do not try to do too many things at once. Make sure you get good sleep, make it a priority. Drinking alcohol can lead to confusion and memory loss, so try to cut down or stop. Also, stop smoking because it reduces the amount of oxygen that gets to your brain. If you are worried about memory loss, talk to your doctor, especially if it affects your ability to live your daily life.

How to use Limbitrol H Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Limbitrol H 12.5 mg/5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Limbitrol H Tablet works

Limbitrol H 12.5 mg/5 mg Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Limbitrol H 12.5 mg/5 mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Limbitrol H 12.5 mg/5 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Limbitrol H 12.5 mg/5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Limbitrol H 12.5 mg/5 mg Tablet may cause side effects which could affect your ability to drive.
As Limbitrol H 12.5 mg/5 mg Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Limbitrol H 12.5 mg/5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Limbitrol H 12.5 mg/5 mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Limbitrol H 12.5 mg/5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Limbitrol H 12.5 mg/5 mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Limbitrol H 12.5 mg/5 mg Tablet
₹2.46/Tablet
Aculip H 12.5 mg/5 mg Tablet
Shine Pharmaceuticals Ltd
₹3.03/Tablet
23% costlier
Amitone Plus Tablet
Intas Pharmaceuticals Ltd
₹3.15/Tablet
28% costlier
₹3.6/Tablet
46% costlier
Amixide-H Tablet
Sun Pharmaceutical Industries Ltd
₹3.9/Tablet
58% costlier
Amitryn-C Tablet
KC Laboratories
₹4.51/Tablet
83% costlier

Patient Concerns

arrow
What would be alternative for this medicine for same salt composition of some lower price. Name of the medicine -- ( Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg tablets USP
Dr. Nabajit Talukdar
Cardiology
Telma h 40/12.5
Stunting done in 2011. All reports including echo are coming normal since then. One medicine cardiac H or remipril is shooting cough. What substitute I can take which can fix cough.?
Dr. Nabajit Talukdar
Cardiology
Stop ramipril start losar h 25/12.5
arrow
Do you have any questions related to Limbitrol H 12.5 mg/5 mg Tablet ?

User Feedback


FAQs

Q. What are the instructions for storage and disposal of Limbitrol H?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Are there any important warnings associated with use of Limbitrol H?

During the first few months of treatment, Limbitrol H may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Q. Can I stop taking Limbitrol H when my symptoms are relieved?

No, you should continue to take Limbitrol H, even if you feel well. If you stop Limbitrol H suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. How to manage weight gain associated with the use of Limbitrol H?

There are reports which suggest that the use of Limbitrol H can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Q. Can the use of Limbitrol H cause sleepiness?

Yes, Limbitrol H can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Limbitrol H affect my sexual life?

The use of Limbitrol H can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Limbitrol H?

No, do not drink alcohol while you are taking Limbitrol H. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Limbitrol H.

Q. Can the use of Limbitrol H change the color of urine?

Yes, Limbitrol H can the change the color of the urine to blue or green. This change of color is expected while using Limbitrol H, and it is not harmful. Your urine color becomes normal once you stop taking Limbitrol H.

Q. How long does Limbitrol H take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Limbitrol H, although some people will start to feel better sooner. When taking Limbitrol H, it is important to give it time to work.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Amitriptyline. North Harrow, Middlesex: Accord Healthcare Limited; 2018. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:External Link
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