Product introduction
Lasilactone 50 Tablet is used to treat resistant hypertension, chronic cardiac failure, and hepatic cirrhosis. It is commonly used when fluid buildup (edema) or high blood pressure cannot be controlled by a single medicine. It helps remove excess salt and water from the body, reducing swelling and fluid overload.
Take Lasilactone 50 Tablet exactly as prescribed by your doctor, preferably with breakfast and/or lunch along with a full glass of water. Avoid taking it in the evening to prevent nighttime urination. For the best results, take the medicine at the same time every day and do not stop on your own, even if you start feeling better.
Continue to follow your doctor’s advice about dietary salt and fluid intake. In conditions like hypertension or heart failure, your doctor may recommend limiting salt, avoiding alcohol, and maintaining a healthy weight. Regular follow-up visits are important, as your doctor may monitor blood pressure, kidney function, and electrolyte levels (especially potassium and sodium).
The most common side effects of Lasilactone 50 Tablet include electrolyte disturbances, hyponatremia (low sodium level in blood), dehydration, and hypovolemia (decreased blood volume). Because this medicine increases urine output, you may feel thirsty or need to urinate more often. To reduce side effects, drink adequate water, avoid excessive sweating or dehydration, and do not use salt substitutes containing potassium unless your doctor advises it.
Do not take Lasilactone 50 Tablet if you have kidney failure, severe liver disease (hepatic encephalopathy), high potassium levels, or low sodium levels, or if you are dehydrated. It is also contraindicated in pregnancy and breastfeeding due to potential harm to the baby. Avoid alcohol and other medicines that may lower blood pressure or increase potassium levels, such as ACE inhibitors, potassium supplements, or certain painkillers (NSAIDs). Be cautious while driving or operating machinery, as dizziness or drowsiness may occur, especially at the start of treatment.
Uses of Lasilactone 50 Tablet
Benefits of Lasilactone 50 Tablet
In Treatment of Resistant Hypertension (high blood pressure)
Lasilactone 50 Tablet helps in the management of resistant hypertension (high blood pressure) that does not respond to standard diuretic therapy. It helps remove excess salt and water from the body and prevents potassium loss. This helps lower blood pressure more effectively in patients with secondary hyperaldosteronism, a condition where excess aldosterone causes fluid buildup and makes blood pressure harder to control.
In Treatment of Chronic Heart Failure
In chronic congestive cardiac failure, the heart struggles to pump blood effectively, leading to fluid buildup in the lungs and body. Lasilactone 50 Tablet helps remove this excess fluid, reducing swelling (edema), breathlessness, and strain on the heart. It is especially useful in resistant edema associated with secondary hyperaldosteronism, where single diuretic therapy is not sufficient.
In Treatment of Liver cirrhosis with edema
In hepatic cirrhosis, impaired liver function often causes fluid accumulation in the abdomen (ascites) and swelling due to secondary hyperaldosteronism. Lasilactone 50 Tablet helps reduce this fluid buildup by removing excess salt and water while maintaining potassium balance and preventing further electrolyte disturbances. It is specifically indicated for resistant edema in patients with hepatic cirrhosis when conventional diuretic therapy alone is inadequate.
Side effects of Lasilactone 50 Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lasilactone 50 Tablet
- Electrolyte imbalance
- Volume depletion
How to use Lasilactone 50 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lasilactone 50 Tablet is to be taken with food.
Avoid Lasilactone 50 Tablet with dietary sodium.
Avoid Lasilactone 50 Tablet with dietary sodium.
How Lasilactone 50 Tablet works
Lasilactone 50 Tablet contains two medicines: furosemide and spironolactone, which act on different parts of the kidney to remove excess fluid. Furosemide is a short-acting loop diuretic that helps the kidneys eliminate sodium, chloride, and water through urine, thereby reducing fluid overload and blood pressure. Spironolactone is a long-acting aldosterone antagonist that promotes the excretion of sodium and water while conserving potassium, helping maintain electrolyte balance and preventing potassium loss during treatment.
Safety advice of Lasilactone 50 Tablet
Alcohol
UNSAFE
It is unsafe to consume alcohol with Lasilactone 50 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Lasilactone 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Lasilactone 50 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Lasilactone 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Lasilactone 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lasilactone 50 Tablet may be needed. Please consult your doctor.
Use of Lasilactone 50 Tablet is not recommended in patients with severe kidney disease.
Use of Lasilactone 50 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Lasilactone 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lasilactone 50 Tablet may be needed. Please consult your doctor.
What if you forget to take Lasilactone 50 Tablet?
If you miss a dose of Lasilactone 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Alternate Brands of Lasilactone 50 Tablet
For informational purposes only. Consult a doctor before taking any medicines.
Lasilactone 50 Tablet
₹6.02/Tablet
Fruselac Tablet
Lupin Ltd
₹5.74/tablet
5% cheaper
Spiromide Tablet
RPG Life Sciences Ltd
₹9.52/tablet
58% costlier
Aldactone F Tablet
RPG Life Sciences Ltd
₹9.52/tablet
58% costlier
Quick tips
- Lasilactone 50 Tablet helps remove excess water from your body.
- Take it in the morning with breakfast to avoid getting up at night to urinate.
- It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.
- Your doctor may regularly monitor your blood pressure, kidney function, and the level of salts such as potassium and sodium in your blood while you're taking this medication.
Fact Box of Lasilactone 50 Tablet
Habit Forming
No
Therapeutic Class
CARDIAC
Patient concerns
User feedback
Patients taking Lasilactone 50 Tablet
Once A Day
100%
What are you using Lasilactone Tablet for?
Edema
41%
Others
25%
Liver cirrhos*
14%
Hypertension *
10%
Heart failure
6%
*Liver cirrhosis with edema, Hypertension (high blood pressure)
How much was the improvement?
Average
40%
Excellent
31%
Poor
28%
What were the side-effects while using Lasilactone 50 Tablet?
No Side Effec*
37%
Decreased cal*
11%
Dehydration
11%
Dizziness
9%
Decreased sod*
7%
*No Side Effect, Decreased calcium level in blood, Decreased sodium level in blood
How do you take Lasilactone Tablet?
Empty stomach
50%
With or witho*
42%
With food
8%
*With or without food
Please rate Lasilactone 50 Tablet on price
Average
48%
Not Expensive
29%
Expensive
24%
FAQs
What are the recommended storage conditions for Lasilactone 50 Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
What are the contraindications associated with the use of Lasilactone 50 Tablet?
The use of Lasilactone 50 Tablet should be avoided in patients with hypersensitivity to furosemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.
What is Lasilactone 50 Tablet?
Lasilactone 50 Tablet is a fixed-dose combination of furosemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients with resistant hypertension, congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), and liver cirrhosis with fluid retention (edema).
Is it safe to use Lasilactone 50 Tablet?
Yes, Lasilactone 50 Tablet is safe for most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.
Can the use of Lasilactone 50 Tablet cause dizziness?
Yes, the use of Lasilactone 50 Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.
Can the use of Lasilactone 50 Tablet cause gout?
Yes, Lasilactone 50 Tablet can cause gout. Lasilactone 50 Tablet contains furosemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Lasilactone 50 Tablet should be avoided in patients with gout.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Frusemide and Spironolactone [Patient Information Sheet]. [Accessed 29th Oct. 2025] (online) Available from:
- CDSCO: Fixed Dose Combinations Approved By DCG (I) Since 1961 to 28th June 2019 [Accessed 29th Oct. 2025] (online) Available from:
Marketer details
Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
Country of origin: India
Expires on or after: March, 2027
A licensed vendor partner from your nearest location will deliver Lasilactone 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2027
A licensed vendor partner from your nearest location will deliver Lasilactone 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹66.84 10% OFF
₹60.2
Inclusive of all taxes
10.0 tablets in 1 strip
New GST benefit included in this MRP, may differ from label
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