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Last updated on:
18 Jan 2019 | 05:30 PM (IST)
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Koxylar 600 mg Tablet


Overview

Uses of Koxylar Tablet

Koxylar 600 mg Tablet is used in the treatment of tuberculosis.

Koxylar Tablet side effects

Common
  • Visual impairment
  • Color blindness

How to use Koxylar Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Koxylar 600 mg Tablet is to be taken with food.

How Koxylar Tablet works

Koxylar 600 mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Koxylar Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Koxylar 600 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Koxylar 600 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Koxylar 600 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Koxylar 600 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Koxylar 600 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Koxylar 600 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Koxylar 600 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Koxylar Tablet?

If you miss a dose of Koxylar 600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Koxylar 600 mg Tablet
₹2.22/Tablet
₹3.48/Tablet
57% costlier
Mycobutol 600 Tablet
Cadila Pharmaceuticals Ltd
₹3.49/Tablet
57% costlier
Ecox 600mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.09/Tablet
39% costlier
Themibutol 600mg Tablet
Themis Medicare Ltd
₹3.37/Tablet
52% costlier
Sunibutol 600mg Tablet
Sunij Pharma Pvt Ltd
₹4.29/Tablet
94% costlier

Expert Advice

  • Koxylar 600 mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Koxylar 600 mg Tablet even if you start to feel better. Stopping early can  can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Interaction with Drugs

Taking Koxylar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Magflux, Magasip
MINOR
Brand(s): Sodamax, Sobinix, Sobimed
MINOR

Patient Concerns

Questions Related to Koxylar

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1) Am I really suffering from diabetes. I am daily doing Ramdev baba Yoga for 1 - 1/30 Hrs 2) I am normal , May I stop Tab Glycomet 500 ? 3) ECG is abnormal but 2D eco is normal. What is a problem? 4) Why Doctor is asking me to take daily Cap. BecoZinc forever. May I stop or continue? 5) I am suffering from Neck spondilites . 6) I feel giddiness, so doctor starts this medicine and asked to take forever for long time May I continue or what ?Plz give me second opinion.
Dr. Sfurti Mann
Diabetes Specialist
Your HbA1c levels will ascertain your diabetes control. You must continue glycometSR. It's dose may even beFor giddiness you may take stemetil MD tab sos and pantop DSR before breakfast
I m cocieved running 9 month n my date of issue is on first week of june.but i m having swelling on foot
Dr. Suman Rao
Gynaecologist
Get your BP, serum proteins and kidney function test done. If all are fine then there is nothing to worry about.
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FAQs

Q. Does Koxylar cause blindness?

Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Koxylar which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. Does Koxylar induce hyperuricemia/how does Koxylar induce hyperuricemia?

Yes. Increase in blood levels of uric acid is a side effect of Koxylar. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys

Q. How does Koxylar work in the body?

Koxylar is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria

Q. What is Koxylar toxicity/How does Koxylar cause optic neuritis/how does Koxylar affect vision?

Koxylar toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Koxylar treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Koxylar induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. What does Koxylar treat?

Koxylar is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Koxylar bacteriostatic or bactericidal?

Koxylar is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)

Q. Is Koxylar hepatotoxic?

Liver toxicities are among the known side effects of Koxylar. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Koxylar) treatment for tuberculosis. Please contact your doctor before taking Koxylar if you have any liver problems

Q. Is Koxylar toxicity reversible?

In most cases Koxylar toxicities are related to dose (depends upon the quantity of Koxylar you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases

Q. Is Koxylar chemotherapy?

Koxylar is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Koxylar is effective against?

Koxylar is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
A-105/2, Okhla Industrial Area, Phase-II, New Delhi-110020
NOT FOR SALE
We do not facilitate sale of this product at present