KC-SPM Tablet SR

Metformin (500mg)+ Pioglitazone (15mg)+ Sitagliptin (100mg)

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KC-SPM Tablet SR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. It controls your blood sugar levels and helps prevent serious complications in the future. Your doctor may prescribe it alone or along with other diabetes medicines.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 01 Mar 2026 | 01:00 AM (IST)

₹145 MRP ₹159.389% off

Gurgaon

KC-SPM Tablet SR is currently sold out

Same composition alternative:

Alsita-MP 500 Tablet SR

₹184~~₹190.75~~

Available alternative from Alkem Laboratories

Sold out

KC-SPM Tablet SR

strip of 10 tablet sr

₹145

~~₹159.38~~

Same composition

Alsita-MP 500 Tablet SR

strip of 10 tablet sr

Metformin (500mg) + Pioglitazone (15mg) + Sitagliptin (100mg)

by Alkem Laboratories Ltd

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₹184

₹15.6 per unit

₹156

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General Information

Contains

Metformin (500mg)+ Pioglitazone (15mg)+ Sitagliptin (100mg)

Marketer

Kollectcare Pvt. Ltd.

Storage

Store below 30°C

The content is shown in English

Product introduction

KC-SPM Tablet SR may be taken on an empty stomach or with a meal. However, the dose will depend on your condition and blood sugar levels; therefore, use it as advised by your doctor and do not stop taking this medicine unless the doctor recommends otherwise. Also, take it regularly and at the same time each day to get the most benefit. It is also crucial to stay on the diet and exercise program recommended by the doctor while taking this medicine.

The most common side effects of this medicine include nausea, vomiting, diarrhea, flatulence, abdominal pain, and constipation. These effects are usually minor and improve with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines, so you need to know how to recognize and deal with it. Contact the doctor if the side effects are worrisome or do not go away.

Before taking KC-SPM Tablet SR, let the doctor know if you have ever had kidney disease, heart or pancreas problems, or drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctors before taking this medicine. Some other medicines you are taking may also interfere with this combination drug; therefore, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may also need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of KC-SPM Tablet SR

Treatment of Type 2 diabetes mellitus

Benefits of KC-SPM Tablet SR

Treatment of Type 2 diabetes mellitus
Lowering blood glucose levels is an essential part of managing diabetes. If you can control these levels, you can reduce the risk of serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking KC-SPM Tablet SR medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of KC-SPM Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of KC-SPM

Nausea
Vomiting
Diarrhea
Flatulence
Constipation
Abdominal pain

How to use KC-SPM Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. KC-SPM Tablet SR may be taken with or without food.

How KC-SPM Tablet SR works

KC-SPM Tablet SR is a combination of three antidiabetic medications. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels). Pioglitazone works by enhancing cellular responsiveness to insulin and increasing insulin-dependent glucose utilization and disposal. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

All substitutes for KC-SPM Tablet SR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Prefer taking KC-SPM Tablet SR after a meal or with a snack, as this will reduce the chance of an upset stomach.
KC-SPM Tablet SR may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety.
If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting.
Monitor your blood sugar regularly while taking this medicine.
Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with KC-SPM Tablet SR

Pregnancy

UNSAFE

KC-SPM Tablet SR is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

KC-SPM Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether KC-SPM Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

KC-SPM Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

KC-SPM Tablet SR is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

What is KC-SPM Tablet SR used for?

KC-SPM Tablet SR is used for adults with type 2 diabetes to help lower high blood sugar when diet and exercise are not enough. It combines three components that work together to control sugar levels throughout the day.

Who should not take KC-SPM Tablet SR?

Individuals should not take KC-SPM Tablet SR if they are allergic to metformin, pioglitazone, or sitagliptin. It should also be avoided in individuals who have severe kidney problems, liver disease, heart failure, current or past bladder cancer, or diabetic ketoacidosis (dangerous build‑up of acids in blood).

Can KC-SPM Tablet SR cause pancreatitis (inflamed pancreas)?

Yes, pancreatitis has been reported with sitagliptin present in KC-SPM Tablet SR. Seek immediate medical attention for severe, persistent belly pain that may reach the back, with or without nausea or vomiting.

Is KC-SPM Tablet SR safe if I have heart problems?

KC-SPM Tablet SR should not be used if you have current or past heart failure. If you recently had a heart attack or have severe circulation or breathing problems, tell your doctor before use.

Can KC-SPM Tablet SR affect my kidneys or require stopping before scans?

Kidney function will be checked regularly during KC-SPM Tablet SR treatment. Stop the product before an iodine contrast scan (X‑ray dye), and restart only when your doctor says it is safe, to lower the risk of lactic acidosis.

Can KC-SPM Tablet SR cause low blood sugar (hypoglycemia)?

KC-SPM Tablet SR alone cannot cause low blood sugar, but low sugar can happen if it is taken with insulin or sulfonylureas. Your doctor may lower those doses, and you should watch for shaking, sweating, a fast heartbeat, hunger, or confusion.

When should I stop or pause KC-SPM Tablet SR?

Stop KC-SPM Tablet SR, and get medical help for signs of lactic acidosis, or a severe allergic reaction (rash, hives, blistering/peeling, swelling of face/lips/tongue, trouble breathing). Your doctor may advise you to pause before major surgery, and during severe dehydration, and follow your doctor’s plan to restart safely.

Can KC-SPM Tablet SR treat type-1 diabetes?

No. KC-SPM Tablet SR cannot treat type-1 diabetes. It is used only for type 2 diabetes.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

La Renon. Metformin+Pioglitazone+Sitagliptin [Product Information]. [Accessed 16 Sep. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kollectcare Pvt. Ltd.
Address: 1102/1103/1104, C Wing, Teerth Technospace, Bengaluru - Mumbai Hwy, Baner, Pune, Maharashtra 411045

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

KC-SPM Tablet SR

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of KC-SPM Tablet SR

Benefits of KC-SPM Tablet SR

Side effects of KC-SPM Tablet SR

How to use KC-SPM Tablet SR

How KC-SPM Tablet SR works

All substitutes for KC-SPM Tablet SR

Alsita-MP 500 Tablet SR

GLUra MP 500 Tablet SR

Sitazit-Trio 500 Tablet SR

Sitara-PM 500 Tablet SR

Ignalis MP 500 Tablet SR

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is KC-SPM Tablet SR used for?

Who should not take KC-SPM Tablet SR?

Can KC-SPM Tablet SR cause pancreatitis (inflamed pancreas)?

Is KC-SPM Tablet SR safe if I have heart problems?

Can KC-SPM Tablet SR affect my kidneys or require stopping before scans?

Can KC-SPM Tablet SR cause low blood sugar (hypoglycemia)?

When should I stop or pause KC-SPM Tablet SR?

Can KC-SPM Tablet SR treat type-1 diabetes?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests