Do not take anticoagulants ('blood thinners') such as warfarin (Coumadin) while you are taking phytonadione unless told to do so by your doctor, If you are taking orlistat (Xenical), take it 2 hours before or 2 hours after taking vitamin K.
- If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using Vitamin K.
- Vitamin K should be used with caution in patients with severe liver disease as the administration of high dosages has resulted in further depression of liver function.
- Routine liver function tests should be performed if regular or prolonged therapy with vitamin K is necessary in patients with liver disease.
- Too much vitamin K can be harmful if you are receiving dialysis treatments due to kidney disease.
Before using this medication, tell your doctor:
- If you have a medical history of blood disorders.
- If you have a medical history of gallbladder disease (e.g., obstructive jaundice, biliary fistula) .
- If you have a medical history of liver or kidney disease.
- If you have recently used or are currently taking an antibiotic.
- If you have recently used or are currently taking a blood thinner such as anisindione, heparin, warfarin, Coumadin.
- If you have recently used or are currently taking salicylates such as aspirin, Backache Relief Extra Strength, Novasal, Nuprin Backache Caplet, Doan's Pills Extra Strength, Pepto-Bismol, Tricosal, and others.
- During pregnancy, this medication should be used only when clearly need.
- Vitamin K alone, with certain other medicines, or with alcohol in some formulations may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to vitamin K.
- Vitamin K in some formulations contains benzyl alcohol, which has been reported to cause toxic and fatal reactions ("gasping syndrome") in newborn children. Discuss any questions or concerns with your doctor.