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Jonvir-ET Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 14 Apr 2026 | 04:21 PM (IST)
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Jonvir-ET Tablet image
Jonvir-ET Tablet image

Product introduction

Jonvir-ET Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach, preferably at bedtime for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine must not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

The most common side effects of this medicine are impaired concentration, abnormal dreams, headache, nausea, weakness and fatigue, nasal congestion, diarrhea, rash, dizziness, trouble sleeping, pain, depression, and cough. These are usually not serious and go away within 2-4 weeks of treatment, however, inform your doctor if they bother you or do not go away. As it can also make you feel dizzy or drowsy, it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or other diseases. Your doctor may suggest some laboratory tests before and during the treatment to check your blood counts, liver and kidney functioning, and other health and mental conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods to prevent transmission of HIV during intercourse.

Uses of Jonvir-ET Tablet

Benefits of Jonvir-ET Tablet

Treatment of HIV infection
Jonvir-ET Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

Side effects of Jonvir-ET Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Jonvir-ET
  • Diarrhea
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Depression
  • Headache
  • Weakness
  • Rash
  • Pain
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Back pain
  • Abdominal pain
  • Anxiety
  • Vomiting
  • Joint pain
  • Pneumonia
  • Dyspepsia
  • Indigestion
  • Muscle pain
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Hypercholesterolemia (high cholesterol)
  • Increased triglyceride level in blood
  • Elevated creatinine kinase
  • Elevated levels of serum amylase
  • Blood in urine
  • Increased transaminase level in blood
  • Cough
  • Impaired concentration
  • Abnormal dreams
  • Dizziness

How to use Jonvir-ET Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jonvir-ET Tablet is to be taken on an empty stomach.

How Jonvir-ET Tablet works

Jonvir-ET Tablet is a combination of three antiviral medicines: Lamivudine, Tenofovir disoproxil fumarate and Efavirenz. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Quick tips

  • Jonvir-ET Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Jonvir-ET Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Jonvir-ET Tablet can cause birth defects. Use effective contraception while taking Jonvir-ET Tablet and 12 weeks after stopping it.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Do not stop taking Jonvir-ET Tablet without your doctor’s advice.
  • Jonvir-ET Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Jonvir-ET Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Jonvir-ET Tablet can cause birth defects. Use effective contraception while taking Jonvir-ET Tablet and 12 weeks after stopping it.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Do not stop taking Jonvir-ET Tablet without your doctor’s advice.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Jonvir-ET Tablet.
Pregnancy

Pregnancy

UNSAFE
Jonvir-ET Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Jonvir-ET Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Jonvir-ET Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Jonvir-ET Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Jonvir-ET Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Jonvir-ET Tablet is used to treat HIV-1 infection in adults and adolescents weighing at least 35 kg. It works by reducing the amount of HIV in the body, helping to keep your immune system strong, and lowering the risk of HIV-related complications.
No, Jonvir-ET Tablet does not cure HIV or AIDS, but it helps control the infection. You will still need to take precautions to avoid spreading HIV to others through blood or sexual contact.
Individuals should not take Jonvir-ET Tablet if they are allergic to any of its ingredients, are taking St. John’s Wort, or are using certain medicines (like voriconazole). Always tell your doctor about all medicines and supplements you use.
Jonvir-ET Tablet is not recommended if you have moderate to severe kidney impairment (creatinine clearance below 50 ml/min), because the dose cannot be adjusted for each medicine present in Jonvir-ET Tablet. Your doctor may suggest alternative medicines.
If you have severe liver disease, your doctor will carefully weigh the benefits and risks before prescribing Jonvir-ET Tablet. Liver function needs to be monitored closely during treatment.
If you have both HIV and hepatitis B or C, Jonvir-ET Tablet may help control both infections. However, stopping it suddenly can cause your hepatitis to flare up, so never stop without your doctor’s advice.
Some people may experience mood changes, depression, anxiety, strange dreams, or trouble sleeping, especially during the first few weeks after using Jonvir-ET Tablet. Contact your doctor immediately if you have severe mood changes or thoughts of self-harm.
Long-term use, especially due to tenofovir (present in Jonvir-ET Tablet), can sometimes reduce bone mineral density, which may weaken bones. Your doctor may monitor your bone health if you are at risk.

Fact Box

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Therapeutic Class

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Johnlee Pharmaceuticals Pvt Ltd
Address: 42/44, Babu Genu Road, Shop No. 06, 2nd Floor, Om Shanti Co-op Housing Society, Kalbadevi Road, Mumbai-400002. (India)

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Jonvir-ET Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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