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IZRA D 30 MG/40 MG CAPSULE

Capsule
Rs.110.25for 1 strip(s) (10 capsules each)
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Composition FOR IZRA D

Domperidone(30mg),Esomeprazole(40mg)

food interaction for IZRA D

alcohol interaction for IZRA D

pregnancy interaction for IZRA D

lactation interaction for IZRA D

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
UNSAFE
Izra d 30 mg/40 mg capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Izra d 30 mg/40 mg capsule is probably safe to use during breastfeeding. Please consult your doctor.
SAFE

SALT INFORMATION FOR IZRA D

Domperidone(30mg)

Uses

Domperidone is used in the treatment of vomiting

How it works

Domperidone indirectly stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine.

Common side effects

Dry mouth
Esomeprazole(40mg)

Uses

Esomeprazole is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

How it works

Esomeprazole lowers the acid production in the stomach.

Common side effects

Nausea, Abdominal pain, Constipation, Diarrhoea, Flatulence

COMMON DOSAGE FOR IZRA D 30 MG/40 MG CAPSULE

Patients taking IZRA D 30 MG/40 MG CAPSULE

  • 89%
    Once A Day
  • 4%
    Twice A Week
  • 4%
    Twice A Day
  • 2%
    Thrice A Day

SUBSTITUTES FOR IZRA D

20 Substitutes
20 Substitutes
Sorted By
RelevancePrice
  • NEXPRO RD 40 CAPSULE
    (10 capsules in strip)
    Torrent Pharmaceuticals Ltd
    Rs. 11.20/capsule
    Capsule
    Rs. 112
    pay 2% more per capsule
  • SOMPRAZ D 40 CAPSULE
    (10 capsules in strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 9.90/capsule
    Capsule
    Rs. 99
    save 10% more per capsule
  • ESOZ D 40 CAPSULE
    (10 capsules in strip)
    Glenmark Pharmaceuticals Ltd
    Rs. 11.70/capsule
    Capsule
    Rs. 117
    pay 6% more per capsule
  • RACIPER D 40 CAPSULE
    (10 capsules in strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 9.90/capsule
    Capsule
    Rs. 99
    save 10% more per capsule
  • ESOMAC D 30MG/40MG CAPSULE
    (10 capsules in strip)
    Cipla Ltd
    Rs. 11/capsule
    Capsule
    Rs. 110
    same price

Top Physicians

Expert advice FOR IZRA D

  • Do not take Domperidone, if you are allergic to it or to any other content in the tablets.
  • Do not take the medicine, if you notice black, tarry stools (bowel motions) or blood in your stools, blockage or tear in the intestines or if you have a tumor of the pituitary gland (prolactinoma).
  • Do not take the drug, if you have moderate to severe liver disease, heart problems (irregular heart rate or heart failure) or abnormal salt levels in the blood.
  • Do not crush or chew the tablets, swallow them whole with a glass of water.
  • Do not take the drug if you intend to drive or operate heavy machinery as it may cause drowsiness.
  • Always take the tablets 15 to 30 minutes before meals and, if needed, before going to bed at night.
  • Consult your doctor, if you are above 60 years of age and taking domperidone for a long period of time.
  • Inform your doctor, if you are already taking medicines for fungal infections (ketoconazole) or antibiotics (e.g. gentamycin, erythromycin).

Frequently asked questions FOR IZRA D

Domperidone

Q. What is Domperidone used for?
Domperidone is used for the treatment of nausea (feeling sick) and vomiting as and when recommended by your doctor.
Q. Is domperidone an over the counter drug?
Domperidone is not an over the counter (OTC) medicine and it is not advisable to take it without a prescription.
Q. Does domperidone cause weight gain?
Weight gain has not been reported with the use of domperidone. If you notice any abnormal weight gain while using domperidone, please talk to your doctor.
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Q. Does domperidone raise the blood pressure?
The increase in blood pressure is generally not seen with the use of domperidone. But if you experience an increase in blood pressure while using domperidone, please consult your doctor.
Q. Can I take domperidone for morning sickness?
Domperidone is not indicated or recommended for treating morning sickness. Please consult your doctor if you plan to take any medicine for treating morning sickness.
Q. How long can I take domperidone for breastfeeding?
Domperidone is not recommended if you are breastfeeding because it passes into breast milk and may affect your baby. Talk to your doctor as either you should not take this medicine or you should stop breastfeeding if you are asked to take it.
Q. Can I take domperidone with antibiotics?
The use of domperidone with antibiotics like erythromycin, levofloxacin, moxifloxacin, spiramycin, and some antifungals is not recommended. Please consult your doctor before using any antibiotics with domperidone.
Q. Can I take domperidone with lansoprazole?
Yes, domperidone can be taken with lansoprazole as no drug-drug interactions have been clinically seen when they are taken together. However, interactions may occur. Please consult your doctor before using the two medicines together.
Q. Can I take domperidone with doxycycline?
Yes, domperidone can be taken with doxycycline. No drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with doxycycline.
Q. Can I take domperidone with omeprazole?
Yes, domperidone can be taken with omeprazole. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor before using the two medicines together.
Q. Can I take domperidone with citalopram?
The use of domperidone with citalopram is not recommended as it may increase the underlying heart problems like prolonged QTc interval. Please consult your doctor before taking the two medicines together.
Q. Can I take domperidone with amitriptyline?
Yes, domperidone can be taken with amitriptyline. No drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with amitriptyline.
Q. Can I take domperidone with amoxicillin?
Yes, domperidone can be taken with amoxicillin. No drug-drug interactions have been reported. However, please consult your doctor before taking domperidone with amoxicillin.
Q. Can I take domperidone with paracetamol?
Yes, domperidone can be taken with paracetamol. No drug--drug interactions have been reported. However, interactions may occur. Please consult your doctor.
Q. Can I take domperidone without food?
It is recommended to take domperidone tablets 15 - 30 minutes before meals.
Q. Can I take domperidone with tramadol?
Yes, domperidone can be taken with tramadol as no drug--drug interactions have been reported. However, please consult your doctor before taking domperidone with tramadol.
Q. Is domperidone safe in pregnancy?
There is limited data on the use of domperidone in pregnant women. Therefore, domperidone should only be used during pregnancy when justified and recommended by the doctor.
Q. Is domperidone safe?
Yes. Domperidone is safe if used at prescribed doses for the prescribed duration as advised by the physician/ doctor.
Q. Is domperidone safe for babies?
Yes, domperidone is safe for use babies if used at prescribed doses and duration as advised by your doctor. Please consult your doctor before giving any medicine to your child.
Q. Is domperidone used for motion sickness?
Domperidone is indicated for use in motion sickness. Please consult your doctor before using domperidone for motion sickness as it must be used in the dose and duration as advised by your doctor.
Q. Is domperidone an antibiotic?
No, domperidone is not an antibiotic. Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick).
Q. Does domperidone cause drowsiness?
Drowsiness has been reported as one of the rare side effects with domperidone. Please talk to your doctor if you experience excessive drowsiness while taking domperidone.
Q. Does domperidone increase milk secretion?
Yes, domperidone can increase milk secretion also known as galactorrhea. This is an uncommon side effect of domperidone. Talk to your doctor if you are experiencing this side effect while taking this medicine.
Q. Does domperidone cause bloating (gas)?
Domperidone can cause some uncommon gastrointestinal side effects like regurgitation, appetite disorder, and heartburn, diarrhoea. However, bloating (gas) has not been reported as a side effect with domperidone.
Q. Does domperidone cause hair loss?
Domperidone has not been reported to cause hair loss. Please consult your doctor in case you experience excessive hair loss while taking domperidone.
Q. Does domperidone help constipation?
Domperidone is not indicated to treat constipation. Please talk to your doctor regarding its use.
Q. Does domperidone cause heart problems?
Domperidone may be associated with an increased risk of heartbeat problem and heart attack. This risk may be more likely in those over 60 years old or taking higher doses. The risk also increases when domperidone is given together with other medicines. Please share your medical history with your doctor if you are prescribed domperidone.
Q. Does domperidone cause constipation?
Yes, domperidone has been seen to cause constipation as a side effect.Consult your doctor if you experience excessive constipation while using domperidone.
Q. Does domperidone relieve bloating (gas)?
Domperidone is an anti-emetic which is used to treat nausea (feeling sick) and vomiting (being sick). It is not indicated to treat bloating (gas). Please consult your doctor before using this medicine.

Esomeprazole

Q. Is esomeprazole available over the counter?
No, esomeprazole is not available as an over-the-counter medication. It is a prescription medicine and is available only when prescribed by a physician.
Q. Can I take esomeprazole with aluminium hydroxide and magnesium carbonate or other antacids?
There is no reported interaction between esomeprazole and antacids. However, antacids increase the pH of the stomach and esomeprazole requires a lower pH for its action and hence there could be a decreased action of esomeprazole if taken with antacids. This interaction can be avoided by taking antacids two hours before or one hour after taking esomeprazole.
Q. Does esomeprazole contain lactose?
Many esomeprazole preparations contain lactose and sucrose. Lactose intolerance has been reported with its use in some patients who cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.
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Q. Is esomeprazole a controlled substance?
Esomeprazole is not a controlled substance. It is available when prescribed by a doctor.
Q. Is esomeprazole safe?
Yes, esomeprazole is safe if taken for prescribed duration in prescribed doses as advised by your doctor.
Q. Does esomeprazole cause weight loss?
Tell your doctor if you experience weight loss with esomeprazole as it may cause damage to your stomach lining on a long term use and weight loss could be an indication of the same.
Q. Does esomeprazole cause hair loss?
Hair loss has been reported as a rare side effect of esomeprazole. Please consult your doctor in case you experience excessive hair fall while you are taking esomeprazole.
Q. Why is esomeprazole better than omeprazole?
Esomeprazole is the S-isomer of omeprazole. Isomers are compounds which have the same molecular formula but different chemical structures. Studies have shown that esomeprazole provides more effective acid control than omeprazole, without any increase in side effects. Furthermore, esomeprazole has a rapid onset of action than omeprazole and less inter-individual variation in acid control.
Q. Does esomeprazole cause palpitations (feeling of rapid, strong heart beat)?
Esomeprazole can lower the magnesium levels in your body and this can cause palpitations. You must get your magnesium levels checked regularly if you are asked to use this medicine for more than three months.
Q. Can a patient undergoing dialysis take esomeprazole?
Esomeprazole can be taken by a patient undergoing dialysis in a manner as prescribed by the doctor. Since esomeprazole is extensively protein bound, it is not expected to be removed by dialysis.
Q. Can esomeprazole be given in the pediatric age group?
The safety and effectiveness of esomeprazole have been established in pediatric patients 1 to 17 years of age for short-term treatment (up to eight weeks) of Gastroesophageal Reflux Disease (GERD). The safety and effectiveness of esomeprazole have been established in pediatric patients 1 month to less than 1 year for short-term treatment (up to 6 weeks) of erosive esophagitis due to acid-mediated GERD. However, the safety and effectiveness of esomeprazole have not been established in patients less than 1 month of age.
Q. Is esomeprazole better than rabeprazole?
The superiority of either esomeprazole or rabeprazole over the other is not clearly defined. One study mentions that rabeprazole (40 mg) is a better choice for mild-to-moderate Gastroesophageal Reflux Disease (GERD) compared with esomeprazole (40 mg) because of its better efficacy and safety profile. Another study mentions that esomeprazole 40 mg provides a more effective and faster acid-inhibitory effect than rabeprazole 20 mg. Also, there are studies which mention that esomeprazole and rabeprazole both are better than the other medicines of the same class (i.e proton pump inhibitors).
Q. Is esomeprazole better than ranitidine?
Esomeprazole is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, treats heartburn, and heals ulcers. Ranitidine is an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal. There are not many studies which compare esomeprazole with ranitidine. However, one study mentions that esomeprazole 40 and 20 mg once daily are effective and well-tolerated therapies compared with ranitidine 150 mg twice daily for healing gastric ulcers.
Q. Can I take esomeprazole with domperidone?
Domperidone is an anti-emetic which can stop you feeling sick. There are no reported drug interactions or harmful effects of using esomeprazole with domperidone. Domperidone can be taken with esomeprazole. Esomeprazole is also available in combination with domperidone.
Q. Can I take esomeprazole with clopidogrel?
Esomeprazole decreases effects of clopidogrel by affecting the metabolism of clopidogrel. Avoid using both drugs together or use an alternate drug.
Q. Can I take esomeprazole with levosulpiride?
Esomeprazole can be taken with levosulpiride. Esomeprazole decreases the acid secretion and levosulpiride increases the intestinal motility. It is safe to use the two medicines together. Esomeprazole is also available as a fixed-dose combination with levosulpiride. This combination helps in the treatment of heartburn, stomach and duodenal ulcers and gastritis.
Q. Is esomeprazole an antacid?
Esomeprazole belongs to the class of proton pump inhibitors (PPIs) which decrease the amount of acid produced in the stomach. It is not an antacid as it does not neutralize the stomach acid by coating the stomach.
Q. Is esomeprazole better than omeprazole or lansoprazole or pantoprazole?
Esomeprazole, omeprazole, lansoprazole and pantoprazole belongs to the same class of medicines with similar action, but their effect may vary upon individual response. Always follow doctor's advice regarding its use.
Q. Can I take esomeprazole with paracetamol (acetaminophen)?
It is safe to take esomeprazole with paracetamol (acetaminophen) as no drug-drug interactions have been reported. However, this does not mean that no interactions exist. Please consult your doctor while taking the two medicines together.
Q. Does esomeprazole cause tinnitus?
Tinnitus has been reported as a rare side effect with esomeprazole (<1% patients taking esomeprazole). Please consult your doctor if you experience tinnitus while taking esomeprazole.
Q. Does esomeprazole has an expiry date?
Yes, esomeprazole does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use esomeprazole after the expiry date.
Q. Is esomeprazole an antibiotic?
No, esomeprazole is not an antibiotic.
Q. Can I take esomeprazole with nitrofurantoin?
Esomeprazole can be taken with nitrofurantoin. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Can I take esomeprazole with ranitidine?
Yes, esomeprazole can be taken with ranitidine. No drug-drug interactions have been seen between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Can I take esomeprazole with ibuprofen?
Esomeprazole can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Can I take esomeprazole with hyoscine?
Esomeprazole can be taken with hyoscine. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Can I take esomeprazole with food?
Esomeprazole should preferably be taken one hour before meals.
Q. Does esomeprazole cause tiredness?
Tiredness is a rare side effect of esomeprazole. Please consult your doctor if you experience excessive tiredness as this may be due to underlying liver abnormalities as esomeprazole breaks down in the liver.
Q. Does esomeprazole cause weight gain?
Weight gain has not be reported to occur with esomeprazole.
Q. Does esomeprazole affect birth control?
Esomeprazole does not seem to affect birth control, as no drug interactions have been reported between esomeprazole and oral birth control pills. It is safe to take the two medications together.
Q. Why is esomeprazole enteric coated?
Esomeprazole is enteric coated to avoid its breakdown by stomach acids and it can reach the intestine and gets absorbed there. Also, the enteric-coated tablets should not be broken or crushed before swallowing.
Q. Can a patient with underlying cardiac disease take esomeprazole?
Patients with the underlying cardiac disease can take esomeprazole. However, esomeprazole can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with the underlying cardiac disease. Patients taking esomeprazole and digoxin may need to be monitored for digoxin toxicity. Esomeprazole decreases the activation of clopidogrel, thus reducing its effects. Patients taking these medicines together needs to be monitored regularly.
Q. Can esomeprazole be given in cancer patients?
Esomeprazole can be taken by cancer patients in a manner as prescribed by the doctor. There are certain studies which have shown that esomeprazole enhanced the antitumor effect of chemotherapy medicines with no added side effects. However, esomeprazole has not been approved for this condition yet. Since cancer patients may also take many other medicines for the primary cancer treatment or for other symptoms and infections, there are chances of drug interactions with esomeprazole. The use of esomeprazole with other drugs should be monitored.
Q. How much time does esomeprazole take to show its effect?
The onset of action of esomeprazole is within 3 hours and lasts for a duration of up to 24 hours.
Q. How is esomeprazole different from pantoprazole?
Esomeprazole and pantoprazole are found to be equally effective in the treatment of Gastroesophageal Reflux Disease (GERD). One study mentions treatment with pantoprazole resulted in significantly faster first-time relief from daytime and night-time GERD-related symptoms than esomeprazole.
Q. Is esomeprazole more effective than lansoprazole?
Yes, esomeprazole is seen to achieve a better acid control and being more effective in rapid relief of heartburn symptoms and acid reflux symptoms as compared to lansoprazole in many research studies. Also, healing rates were consistently high with esomeprazole.
Q. Can I take esomeprazole with sodium bicarbonate as a buffer?
Sodium bicarbonate buffer protects against acid degradation of esomeprazole in addition to immediate antacid action. Esomeprazole can be taken with sodium bicarbonate as a buffer only in a manner as prescribed by the doctor.
Q. Can I take esomeprazole with naproxen?
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) which works by reducing inflammation and pain in the body. There are no reported drug interactions or harmful effects of using esomeprazole with naproxen. Esomeprazole and naproxen can be taken together.
Q. Is esomeprazole a narcotic?
Esomeprazole is not a narcotic. It belongs to the class of proton pump inhibitors.

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Content on this page was last updated on 03 April, 2017, by Dr. Varun Gupta (MD Pharmacology)