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    Domperidone + Esomeprazole

    Information about Domperidone + Esomeprazole

    Domperidone + esomeprazole uses

    Domperidone+Esomeprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and functional dyspepsia.

    How domperidone + esomeprazole works

    This is a combination of two medicines: Domperidone and Esomeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Esomeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

    Common side effects of domperidone + esomeprazole

    Diarrhea, Flatulence, Stomach pain, Dryness in mouth, Headache
    Content Details
    Written By
    Dr. Betina Chandolia
    MDS, BDS
    Reviewed By
    Dr. Lalit Kanodia
    MD (Pharmacology), MBBS
    Last updated on:
    18 Feb 2020 | 05:24 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Domperidone + Esomeprazole

    • ₹98 to ₹149
      Torrent Pharmaceuticals Ltd
      2 variant(s)
    • ₹107 to ₹183
      Sun Pharmaceutical Industries Ltd
      3 variant(s)
    • ₹106 to ₹154
      Glenmark Pharmaceuticals Ltd
      2 variant(s)
    • ₹136
      Micro Labs Ltd
      1 variant(s)
    • ₹80 to ₹147
      Cipla Ltd
      2 variant(s)
    • ₹41
      Mankind Pharma Ltd
      1 variant(s)
    • ₹88 to ₹147
      Torrent Pharmaceuticals Ltd
      2 variant(s)
    • ₹132
      Lupin Ltd
      1 variant(s)
    • ₹108
      La Renon Healthcare Pvt Ltd
      1 variant(s)
    • ₹40
      Blue Cross Laboratories Ltd
      1 variant(s)

    Expert advice for Domperidone + Esomeprazole

    • You have been prescribed Domperidone + Esomeprazole for the treatment of acidity and heartburn.
    • Take it one hour before the meal, preferably in the morning.
    • It is a well-tolerated medicine and provides relief for a long time.
    • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
    • Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
    • Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

    Frequently asked questions for Domperidone + Esomeprazole

    Domperidone + Esomeprazole

    Q. What is Domperidone+Esomeprazole?

    Domperidone+Esomeprazole is a combination of two medicines: Domperidone and Esomeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.

    Q. Is it safe to use Domperidone+Esomeprazole?

    Yes, Domperidone+Esomeprazole is safe for most of the patients. However, in some patients it may cause common side effects like diarrhoea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.

    Q. What is the best time to take Domperidone+Esomeprazole?

    It is best to take Domperidone+Esomeprazole before the first meal of the day or on an empty stomach.

    Q. Can the use of Domperidone+Esomeprazole cause abnormal heartbeat?

    Yes, the use of Domperidone+Esomeprazole can increase the risk of irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.

    Q. What are the contraindications associated with the use of Domperidone+Esomeprazole?

    The use of Domperidone+Esomeprazole is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.

    Q. Can the use of Domperidone+Esomeprazole cause dry mouth?

    Yes, the use of Domperidone+Esomeprazole can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.

    Q. Can the use of Domperidone+Esomeprazole cause diarrhea?

    Yes, the use of Domperidone+Esomeprazole can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequency of urination and dark colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.

    Q. What are the storage conditions for Domperidone+Esomeprazole?

    Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

    Content on this page was last updated on 18 February, 2020, by Dr. Varun Gupta (MD Pharmacology)