Istamet G 50mg/1mg/1000mg Tablet IR
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Product introduction
Istamet G 50mg/1mg/1000mg Tablet IR is a combination of three medicines used to lower blood glucose levels in people with type 2 diabetes mellitus. It is generally prescribed when diet, exercise, and other treatments do not result in adequate glycemic control.
Istamet G 50mg/1mg/1000mg Tablet IR is best taken with food; however, take this medicine regularly and at the same time each day to get maximum benefits. The dose and duration are decided according to your condition and how well you respond to it. The doctor may also monitor your blood sugar levels regularly when you are taking this combination medicine.
Keep taking this medicine even if you feel well or your blood sugar levels are controlled. If stopped abruptly, your blood sugar levels could rise and put you at risk of complications. This medication is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction because lifestyle habits play a big part in controlling diabetes.
The most common side effects of Istamet G 50mg/1mg/1000mg Tablet IR include nausea, vomiting, gastrointestinal disturbances, and hypoglycemia. Let your doctor know if any of these side effects do not go away or get worse. They may be able to help by adjusting the dosage or by prescribing an alternate medicine.
You should not take Istamet G 50mg/1mg/1000mg Tablet IR if you have type 1 diabetes mellitus or acute or chronic metabolic acidosis, including diabetic ketoacidosis. Patients with active bladder cancer or a history of bladder cancer should also not take this medicine. Inform your doctor about all the other medicines that you take as some of them can affect or be affected by this medication. Pregnant or breastfeeding women should also consult their doctors before taking it.
Uses of Istamet G Tablet IR
Benefits of Istamet G Tablet IR
In Treatment of Type 2 diabetes mellitus
Lowering blood glucose levels is an essential part of managing diabetes as this helps to reduce the risk of serious diabetes-associated complications, such as kidney damage, eye damage, nerve problems, and loss of limbs. Istamet G 50mg/1mg/1000mg Tablet IR helps control high blood glucose (sugar) levels. It also reduces the risk of heart diseases like heart attack or stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Side effects of Istamet G Tablet IR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Istamet G
- Hypoglycemia (low blood glucose level)
- Headache
- Nausea
- Gastrointestinal disturbance
- Diarrhea
- Abdominal pain
- Constipation
- Vomiting
How to use Istamet G Tablet IR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istamet G 50mg/1mg/1000mg Tablet IR is to be taken with food.
How Istamet G Tablet IR works
Istamet G 50mg/1mg/1000mg Tablet IR is a combination of three antidiabetic medications. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood. Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Istamet G 50mg/1mg/1000mg Tablet IR.
Pregnancy
CONSULT YOUR DOCTOR
Istamet G 50mg/1mg/1000mg Tablet IR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Istamet G 50mg/1mg/1000mg Tablet IR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Istamet G 50mg/1mg/1000mg Tablet IR should be used with caution in patients with severe kidney disease. Dose adjustment of Istamet G 50mg/1mg/1000mg Tablet IR may be needed. Please consult your doctor.
Liver
CAUTION
Istamet G 50mg/1mg/1000mg Tablet IR should be used with caution in patients with severe liver disease. Dose adjustment of Istamet G 50mg/1mg/1000mg Tablet IR may be needed. Please consult your doctor.
What if you forget to take Istamet G Tablet IR?
If you miss a dose of Istamet G 50mg/1mg/1000mg Tablet IR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Prefer taking Istamet G 50mg/1mg/1000mg Tablet IR after a meal or with a snack, as this will reduce the chance of an upset stomach.
- Istamet G 50mg/1mg/1000mg Tablet IR may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety.
- If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting.
- Monitor your blood sugar regularly while taking this medicine.
- Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
FAQs
What is Istamet G 50mg/1mg/1000mg Tablet IR used for in diabetes?
Istamet G 50mg/1mg/1000mg Tablet IR is used to treat type 2 diabetes mellitus in adults when diet and exercise alone or along with other blood sugar-lowering medicines aren’t enough to control blood sugar. It helps lower blood sugar levels, improve insulin response, and reduce the risk of complications from long-term diabetes.
When should I take Istamet G 50mg/1mg/1000mg Tablet IR?
Istamet G 50mg/1mg/1000mg Tablet IR should be taken once or twice daily with meals, depending on your doctor's prescription. Taking the medicine with food reduces the chance of stomach upset and lowers the risk of low blood sugar (hypoglycemia).
Can I take Istamet G 50mg/1mg/1000mg Tablet IR if I have kidney or liver issues?
No. Istamet G 50mg/1mg/1000mg Tablet IR is not recommended for patients with severe kidney or liver problems, as it may increase the risk of lactic acidosis, low blood sugar, or medication buildup in the body. Your doctor will assess kidney function before prescribing.
Are there any side effects of Istamet G 50mg/1mg/1000mg Tablet IR?
The common side effects of Istamet G 50mg/1mg/1000mg Tablet IR may include nausea, upset stomach, diarrhea, or constipation, headache, hypoglycemia (low blood sugar), weight gain, etc. If you experience severe side effects like difficulty breathing, chest pain, or signs of lactic acidosis (e.g., muscle pain, weakness, or dizziness), contact your doctor immediately.
Can I drink alcohol while taking Istamet G 50mg/1mg/1000mg Tablet IR?
Avoid alcohol while taking Istamet G 50mg/1mg/1000mg Tablet IR, as it can increase the risk of side effects like hypoglycemia (low blood sugar) or lactic acidosis (a serious condition caused by metformin present in Istamet G 50mg/1mg/1000mg Tablet IR).
How long does it take for Istamet G 50mg/1mg/1000mg Tablet IR to work?
You may start noticing improvements in blood sugar levels within a few days. However, it may take a few weeks to months to see the full benefits.
Can I stop taking Istamet G 50mg/1mg/1000mg Tablet IR if my blood sugar improves?
No, do not stop taking Istamet G 50mg/1mg/1000mg Tablet IR without consulting your doctor. Stopping the medication abruptly can cause your blood sugar levels to rise again. Always follow your doctor's instructions.
What should I avoid while taking Istamet G 50mg/1mg/1000mg Tablet IR?
Avoid high-sugar or high-carbohydrate foods, as they can affect blood sugar control; limit alcohol consumption, as it can increase the risk of side effects; and avoid skipping meals, as it may lead to low blood sugar, etc.
What tests should I regularly monitor while taking Istamet G 50mg/1mg/1000mg Tablet IR?
While on Istamet G 50mg/1mg/1000mg Tablet IR treatment, your doctor may advise you to regularly check fasting and post-meal blood glucose, HbA1c (every 3 months), kidney and liver function tests, vitamin B12 levels, and weight and blood pressure. These help ensure your diabetes is well managed and prevent complications.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sitagliptin/metformin HC [Prescribing Information]. Whitehouse Station: Merck & Co., Inc.; 2012. [Accessed 02 Nov. 2023] (online) Available from:
- A Multicenter, Randomized, Comparative, Active-Controlled, Double-Blind, Double-Dummy, Phase 3 Study to Assess Efficacy and Safety of Fixed Dose Combination of Sitagliptin Phosphate, Metformin Hydrochloride and Glimepiride Tablets in Comparison to Co- administration of Metformin Hydrochloride and Glimepiride Tablets in Patients with Type 2 Diabetes Mellitus. Protocol No. ICR/21/004, clinical study report dated 3rd July 2023, Sun Pharma Laboratories Limited, Data on file.
Marketer details
Name: Sun Pharma Laboratories Ltd
Address: Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Country of origin: India
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MRP
₹133.59
Inclusive of all taxes
10.0 tablet ir in 1 strip
SOLD OUT
Available alternative with same salt composition
Sitaxa GM 50mg/1mg/1000mg Tablet IR
strip of 10 tablet ir
by Torrent Pharmaceuticals Ltd
₹137
5% off
Sitagliptin (50mg) + Glimepiride (1mg) + Metformin (1000mg)