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Istamet G 50mg/1mg/1000mg Tablet IR

Istamet G 50mg/1mg/1000mg Tablet IR

10 tablet ir
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Product expires after Feb, 2027

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Product introduction

Istamet G 50mg/1mg/1000mg Tablet IR is a combination of three medicines used to lower blood glucose levels in people with type 2 diabetes mellitus. It is generally prescribed when diet, exercise, and other treatments do not result in adequate glycemic control.


Istamet G 50mg/1mg/1000mg Tablet IR is best taken with food; however, take this medicine regularly and at the same time each day to get maximum benefits. The dose and duration are decided according to your condition and how well you respond to it. The doctor may also monitor your blood sugar levels regularly when you are taking this combination medicine.


Keep taking this medicine even if you feel well or your blood sugar levels are controlled. If stopped abruptly, your blood sugar levels could rise and put you at risk of complications. This medication is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction because lifestyle habits play a big part in controlling diabetes.


The most common side effects of Istamet G 50mg/1mg/1000mg Tablet IR include nausea, vomiting, gastrointestinal disturbances, and hypoglycemia. Let your doctor know if any of these side effects do not go away or get worse. They may be able to help by adjusting the dosage or by prescribing an alternate medicine.


You should not take Istamet G 50mg/1mg/1000mg Tablet IR if you have type 1 diabetes mellitus or acute or chronic metabolic acidosis, including diabetic ketoacidosis. Patients with active bladder cancer or a history of bladder cancer should also not take this medicine. Inform your doctor about all the other medicines that you take as some of them can affect or be affected by this medication. Pregnant or breastfeeding women should also consult their doctors before taking it.

Uses of Istamet G Tablet IR

Benefits of Istamet G Tablet IR

Treatment of Type 2 diabetes mellitus
Lowering blood glucose levels is an essential part of managing diabetes as this helps to reduce the risk of serious diabetes-associated complications, such as kidney damage, eye damage, nerve problems, and loss of limbs. Istamet G 50mg/1mg/1000mg Tablet IR helps control high blood glucose (sugar) levels. It also reduces the risk of heart diseases like heart attack or stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Istamet G Tablet IR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Istamet G
  • Diarrhea
  • Abdominal pain
  • Hypoglycemia (low blood glucose level)
  • Vomiting
  • Nausea
  • Taste change
  • Loss of appetite

How to use Istamet G Tablet IR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istamet G 50mg/1mg/1000mg Tablet IR should be taken with or after food.

How Istamet G Tablet IR works

Istamet G 50mg/1mg/1000mg Tablet IR is a combination of three antidiabetic medications. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood. Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels).

Quick tips

  • Prefer taking Istamet G 50mg/1mg/1000mg Tablet IR after a meal or with a snack, as this will reduce the chance of an upset stomach.
  • Istamet G 50mg/1mg/1000mg Tablet IR may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety.
  • If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting.
  • Monitor your blood sugar regularly while taking this medicine.
  • Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.
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10 tablet ir
MRP may vary by batch. Any additional charges, including packaging, handling, shipping or delivery charges, will be clearly disclosed before purchase.
Generic alternative available
Contains Sitagliptin (50mg) + Glimepiride (1mg) + Metformin (1000mg)
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Istamet G 50mg/1mg/1000mg Tablet IR
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Zoryl MS 50mg/1mg/1000mg Tablet IR
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